P40222: Alpha-taxilin
Protein names | - Alpha-taxilin |
---|---|
Gene names | TXLNA |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P40222 |
6
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKNQDKKNGA AKQSNPKSSP GQPEAGPEGA QERPSQAAPA VEAEGPGSSQ APRKPEGAQA
70 80 90 100 110 120
RTAQSGALRD VSEELSRQLE DILSTYCVDN NQGGPGEDGA QGEPAEPEDA EKSRTYVARN
130 140 150 160 170 180
GEPEPTPVVN GEKEPSKGDP NTEEIRQSDE VGDRDHRRPQ EKKKAKGLGK EITLLMQTLN
190 200 210 220 230 240
TLSTPEEKLA ALCKKYAELL EEHRNSQKQM KLLQKKQSQL VQEKDHLRGE HSKAVLARSK
250 260 270 280 290 300
LESLCRELQR HNRSLKEEGV QRAREEEEKR KEVTSHFQVT LNDIQLQMEQ HNERNSKLRQ
310 320 330 340 350 360
ENMELAERLK KLIEQYELRE EHIDKVFKHK DLQQQLVDAK LQQAQEMLKE AEERHQREKD
370 380 390 400 410 420
FLLKEAVESQ RMCELMKQQE THLKQQLALY TEKFEEFQNT LSKSSEVFTT FKQEMEKMTK
430 440 450 460 470 480
KIKKLEKETT MYRSRWESSN KALLEMAEEK TVRDKELEGL QVKIQRLEKL CRALQTERND
490 500 510 520 530 540
LNKRVQDLSA GGQGSLTDSG PERRPEGPGA QAPSSPRVTE APCYPGAPST EASGQTGPQE
PTSARA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
6 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P40222-1-unknown | MKNQDK... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P40222-43- | AEGPGS... | 43 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P40222-92-unknown | QGGPGE... | 92 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11491 | |||
P40222-93- | GGPGED... | 93 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
P40222-93- | GGPGED... | 93 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P40222-93- | GGPGED... | 93 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P40222-93- | GGPGED... | 93 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P40222-93- | GGPGED... | 93 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P40222-93-unknown | GGPGED... | 93 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P40222-99-unknown | GAQGEP... | 99 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11492 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...CVDNNQ | 91 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11491 | |||
...GPGEDG | 98 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11492 | |||
...TSARA | 546 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 91 | DNNQ.|.QGGP | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
GRAB_HUMAN | 98 | GEDG.|.GAQG | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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