O95810: Caveolae-associated protein 2 {ECO:0000312|HGNC:HGNC:10690}

General Information

Protein names	- Caveolae-associated protein 2 {ECO:0000312\|HGNC:HGNC:10690} - Cavin-2 - PS-p68 - Phosphatidylserine-binding protein - Serum deprivation-response protein
Gene names	SDPR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95810

7 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGEDAAQAEK FQHPGSDMRQ EKPSSPSPMP SSTPSPSLNL GNTEEAIRDN SQVNAVTVLT
        70         80         90        100        110        120
LLDKLVNMLD AVQENQHKME QRQISLEGSV KGIQNDLTKL SKYQASTSNT VSKLLEKSRK
       130        140        150        160        170        180
VSAHTRAVKE RMDRQCAQVK RLENNHAQLL RRNHFKVLIF QEENEIPASV FVKQPVSGAV
       190        200        210        220        230        240
EGKEELPDEN KSLEETLHTV DLSSDDDLPH DEEALEDSAE EKVEESRAEK IKRSSLKKVD
       250        260        270        280        290        300
SLKKAFSRQN IEKKMNKLGT KIVSVERREK IKKSLTSNHQ KISSGKSSPF KVSPLTFGRK
       310        320        330        340        350        360
KVREGESHAE NETKSEDLPS SEQMPNDQEE ESFAEGHSEA SLASALVEGE IAEEAAEKAT
       370        380        390        400        410        420
SRGSNSGMDS NIDLTIVEDE EEESVALEQA QKVRYEGSYA LTSEEAERSD GDPVQPAVLQ

VHQTS

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95810-2-unknown	MGEDAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95810-2-Acetylation	GEDAAQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95810-2-Acetylation	GEDAAQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95810-178-unknown	GAVEGK...	178			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
O95810-276-unknown	TSNHQK...	276		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13907
O95810-351-unknown	IAEEAA...	351		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11032
O95810-380-unknown	EEEESV...	380		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11033
O95810-398-unknown	SYALTS...	398			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...IKKSLT	275	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13907
...LVEGEI	350	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11032
...TIVEDE	379	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11033
...VHQTS	425	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...VHQTS	425		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...VHQTS	425		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	275	KSLT.\|.TSNH	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	350	EGEI.\|.IAEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	379	VEDE.\|.EEEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)