O75995: SAM and SH3 domain-containing protein 3
Protein names | - SAM and SH3 domain-containing protein 3 - SH3 protein expressed in lymphocytes homolog |
---|---|
Gene names | SASH3 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O75995 |
13
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLRRKPSNAS EKEPTQKKKL SLQRSSSFKD FAKSKPSSPV VSEKEFNLDD NIPEDDSGVP
70 80 90 100 110 120
TPEDAGKSGK KLGKKWRAVI SRTMNRKMGK MMVKALSEEM ADTLEEGSAS PTSPDYSLDS
130 140 150 160 170 180
PGPEKMALAF SEQEEHELPV LSRQASTGSE LCSPSPGSGS FGEEPPAPQY TGPFCGRARV
190 200 210 220 230 240
HTDFTPSPYD HDSLKLQKGD VIQIIEKPPV GTWLGLLNGK VGSFKFIYVD VLPEEAVGHA
250 260 270 280 290 300
RPSRRQSKGK RPKPKTLHEL LERIGLEEHT STLLLNGYQT LEDFKELRET HLNELNIMDP
310 320 330 340 350 360
QHRAKLLTAA ELLLDYDTGS EEAEEGAESS QEPVAHTVSE PKVDIPRDSG CFEGSESGRD
370 380
DAELAGTEEQ LQGLSLAGAP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
13 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O75995-1-unknown | MLRRKP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O75995-25- | SSSFKD... | 25 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
O75995-30- | DFAKSK... | 30 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O75995-95- | ALSEEM... | 95 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O75995-95- | ALSEEM... | 95 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O75995-103-unknown | TLEEGS... | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10977 | |||
O75995-116- | YSLDSP... | 116 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-116- | YSLDSP... | 116 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O75995-116- | YSLDSP... | 116 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O75995-116- | YSLDSP... | 116 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O75995-117- | SLDSPG... | 117 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-127-unknown | ALAFSE... | 127 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O75995-127- | ALAFSE... | 127 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
O75995-128- | LAFSEQ... | 128 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-128- | LAFSEQ... | 128 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O75995-128- | LAFSEQ... | 128 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O75995-128- | LAFSEQ... | 128 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O75995-129-unknown | AFSEQE... | 129 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
O75995-129-unknown | AFSEQE... | 129 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
O75995-129- | AFSEQE... | 129 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O75995-130- | FSEQEE... | 130 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O75995-130- | FSEQEE... | 130 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EEMADT | 102 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10977 | |||
...LAGAP | 380 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 102 | MADT.|.TLEE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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