Q8N9T8: Protein KRI1 homolog

General Information

Protein names	- Protein KRI1 homolog
Gene names	KRI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8N9T8

6 N-termini

8 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEPRGSSQL RVNAAFAARY NRYREREELQ RLKDRYGDRD SSSDSSSESD SSDERVEFDP
        70         80         90        100        110        120
QQERDFYKTL SLLKKKDPRI YQKDATFYNR TASSSDSEED PEALEKQKKV RPMYLKDYER
       130        140        150        160        170        180
KVILEKAGKY VDEENSDGET SNHRLQETSS QSYVEEQKQL KESFRAFVED SEDEDGAGEG
       190        200        210        220        230        240
GSSLLQKRAK TRQEKAQEEA DYIEWLKGQK EIRNPDSLKE LTHLKEYWND PELDEGERFL
       250        260        270        280        290        300
RDYILNKRYE EEEEEEEDEE EMEEEEGVHG PPVQLAVDDS SDEGELFLKK QEDFEQKYNF
       310        320        330        340        350        360
RFEEPDSASV KTYPRSIASS VRRKDERRKE KREETRERKK REKAKKQEEL KQLKNLKRKE
       370        380        390        400        410        420
ILAKLEKLRK VTGNEMLGLE EGDLEDDFDP AQHDQLMQKC FGDEYYGAVE EEKPQFEEEE
       430        440        450        460        470        480
GLEDDWNWDT WDGPEQEGDW SQQELHCEDP NFNMDADYDP SQPRKKKREA PLTGKKKRKS
       490        500        510        520        530        540
PFAAAVGQEK PVFEPGDKTF EEYLDEYYRL DYEDIIDDLP CRFKYRTVVP CDFGLSTEEI
       550        560        570        580        590        600
LAADDKELNR WCSLKKTCMY RSEQEELRDK RAYSQKAQNS WKKRQVFKSL CREEAETPAE
       610        620        630        640        650        660
ATGKPQRDEA GPQRQLPALD GSLMGPESPP AQEEEAPVSP HKKPAPQKRR RAKKARLLGP
       670        680        690        700
TVMLGGCEFS RQRLQAFGLN PKRLHFRQLG RQRRKQQGPK NSS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

6 N-termini - 8 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8N9T8-1-unknown	MPEPRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8N9T8-4-unknown	PRGSSQ...	4	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000445789
Q8N9T8-120-unknown	RKVILE...	120	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12880
Q8N9T8-313-unknown	YPRSIA...	313	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12881
Q8N9T8-313-unknown	YPRSIA...	313	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2273
Q8N9T8-313-	YPRSIA...	313		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8N9T8-313-	YPRSIA...	313		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q8N9T8-387-unknown	DFDPAQ...	387	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12882

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LKDYER	119	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12880
...DYILNK	246	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000438000
...ASVKTY	312	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12881
...ASVKTY	312	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2273
...GDLEDD	386	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12882
...LSTEEI	539	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000445789
...PKNSS	703	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...	709		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...	709		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...	709		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	119	DYER.\|.RKVI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	312	VKTY.\|.YPRS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CASP3_HUMAN	312	VKTY.\|.YPRS	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> KRI1_HUMAN @312
GRAB_HUMAN	386	LEDD.\|.DFDP	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)