Q9P1Q0: Vacuolar protein sorting-associated protein 54

General Information

Protein names	- Vacuolar protein sorting-associated protein 54 - Hepatocellular carcinoma protein 8 - Tumor antigen HOM-HCC-8 - Tumor antigen SLP-8p
Gene names	VPS54
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9P1Q0

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD
        70         80         90        100        110        120
QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY
       130        140        150        160        170        180
QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN
       190        200        210        220        230        240
SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE
       250        260        270        280        290        300
LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ
       310        320        330        340        350        360
PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST
       370        380        390        400        410        420
YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK
       430        440        450        460        470        480
VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL
       490        500        510        520        530        540
DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA
       550        560        570        580        590        600
SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ
       610        620        630        640        650        660
ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL
       670        680        690        700        710        720
LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS
       730        740        750        760        770        780
GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF
       790        800        810        820        830        840
NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML
       850        860        870        880        890        900
RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA
       910        920        930        940        950        960
IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK
       970
GLKDLDLNMA EIWEQKR

Isoforms

- Isoform 2 of Vacuolar protein sorting-associated protein 54 - Isoform 3 of Vacuolar protein sorting-associated protein 54 - Isoform 4 of Vacuolar protein sorting-associated protein 54 - Isoform 5 of Vacuolar protein sorting-associated protein 54

Sequence View

        10         20         30         40         50         60
MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD
        70         80         90        100        110        120
QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY
       130        140        150        160        170        180
QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN
       190        200        210        220        230        240
SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE
       250        260        270        280        290        300
LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ
       310        320        330        340        350        360
PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST
       370        380        390        400        410        420
YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK
       430        440        450        460        470        480
VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL
       490        500        510        520        530        540
DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA
       550        560        570        580        590        600
SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ
       610        620        630        640        650        660
ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL
       670        680        690        700        710        720
LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS
       730        740        750        760        770        780
GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF
       790        800        810        820        830        840
NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML
       850        860        870        880        890        900
RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA
       910        920        930        940        950        960
IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK
       970
GLKDLDLNMA EIWEQKR         10         20         30         40         50         60
MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD
        70         80         90        100        110        120
QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY
       130        140        150        160        170        180
QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN
       190        200        210        220        230        240
SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE
       250        260        270        280        290        300
LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ
       310        320        330        340        350        360
PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST
       370        380        390        400        410        420
YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK
       430        440        450        460        470        480
VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL
       490        500        510        520        530        540
DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA
       550        560        570        580        590        600
SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ
       610        620        630        640        650        660
ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL
       670        680        690        700        710        720
LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS
       730        740        750        760        770        780
GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF
       790        800        810        820        830        840
NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML
       850        860        870        880        890        900
RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA
       910        920        930        940        950        960
IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK
       970
GLKDLDLNMA EIWEQKR         10         20         30         40         50         60
MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD
        70         80         90        100        110        120
QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY
       130        140        150        160        170        180
QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN
       190        200        210        220        230        240
SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE
       250        260        270        280        290        300
LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ
       310        320        330        340        350        360
PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST
       370        380        390        400        410        420
YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK
       430        440        450        460        470        480
VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL
       490        500        510        520        530        540
DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA
       550        560        570        580        590        600
SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ
       610        620        630        640        650        660
ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL
       670        680        690        700        710        720
LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS
       730        740        750        760        770        780
GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF
       790        800        810        820        830        840
NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML
       850        860        870        880        890        900
RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA
       910        920        930        940        950        960
IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK
       970
GLKDLDLNMA EIWEQKR         10         20         30         40         50         60
MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD
        70         80         90        100        110        120
QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY
       130        140        150        160        170        180
QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN
       190        200        210        220        230        240
SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE
       250        260        270        280        290        300
LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ
       310        320        330        340        350        360
PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST
       370        380        390        400        410        420
YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK
       430        440        450        460        470        480
VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL
       490        500        510        520        530        540
DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA
       550        560        570        580        590        600
SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ
       610        620        630        640        650        660
ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL
       670        680        690        700        710        720
LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS
       730        740        750        760        770        780
GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF
       790        800        810        820        830        840
NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML
       850        860        870        880        890        900
RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA
       910        920        930        940        950        960
IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK
       970
GLKDLDLNMA EIWEQKR

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9P1Q0-1-unknown	MASSHS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9P1Q0-1-unknown	MASSHS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94285
Q9P1Q0-1-unknown	MASSHS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94287
Q9P1Q0-431-unknown	VVVKLA...	431	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13483
Q9P1Q0-431-unknown	VVVKLA...	431	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149295
Q9P1Q0-431-unknown	VVVKLA...	431	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152324
Q9P1Q0-431-unknown	VVVKLA...	431	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152488
Q9P1Q0-839-unknown	MLRHFD...	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94288
Q9P1Q0-839-unknown	MLRHFD...	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100460
Q9P1Q0-839-unknown	MLRHFD...	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100459
Q9P1Q0-839-unknown	MLRHFD...	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100461

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EIDTDV	430	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13483
...EIDTDV	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135735
...EIDTDV	430	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135899
...WEQKR	977	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...WEQKR	977	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89906
...WEQKR	977	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89904
...WEQKR	977	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89905

TopFIND

Q9P1Q0: Vacuolar protein sorting-associated protein 54

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Evidence Codes:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates