Q9NRL2: Bromodomain adjacent to zinc finger domain protein 1A
Protein names | - Bromodomain adjacent to zinc finger domain protein 1A - ATP-dependent chromatin-remodeling protein - ATP-utilizing chromatin assembly and remodeling factor 1 - hACF1 - CHRAC subunit ACF1 - Williams syndrome transcription factor-related chromatin-remodeling factor 180 - WCRF180 - hWALp1 |
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Gene names | BAZ1A |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9NRL2 |
6
N-termini
5
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPLLHRKPFV RQKPPADLRP DEEVFYCKVT NEIFRHYDDF FERTILCNSL VWSCAVTGRP
70 80 90 100 110 120
GLTYQEALES EKKARQNLQS FPEPLIIPVL YLTSLTHRSR LHEICDDIFA YVKDRYFVEE
130 140 150 160 170 180
TVEVIRNNGA RLQCRILEVL PPSHQNGFAN GHVNSVDGET IIISDSDDSE TQSCSFQNGK
190 200 210 220 230 240
KKDAIDPLLF KYKVQPTKKE LHESAIVKAT QISRRKHLFS RDKLKLFLKQ HCEPQDGVIK
250 260 270 280 290 300
IKASSLSTYK IAEQDFSYFF PDDPPTFIFS PANRRRGRPP KRIHISQEDN VANKQTLASY
310 320 330 340 350 360
RSKATKERDK LLKQEEMKSL AFEKAKLKRE KADALEAKKK EKEDKEKKRE ELKKIVEEER
370 380 390 400 410 420
LKKKEEKERL KVEREKEREK LREEKRKYVE YLKQWSKPRE DMECDDLKEL PEPTPVKTRL
430 440 450 460 470 480
PPEIFGDALM VLEFLNAFGE LFDLQDEFPD GVTLEVLEEA LVGNDSEGPL CELLFFFLTA
490 500 510 520 530 540
IFQAIAEEEE EVAKEQLTDA DTKDLTEALD EDADPTKSAL SAVASLAAAW PQLHQGCSLK
550 560 570 580 590 600
SLDLDSCTLS EILRLHILAS GADVTSANAK YRYQKRGGFD ATDDACMELR LSNPSLVKKL
610 620 630 640 650 660
SSTSVYDLTP GEKMKILHAL CGKLLTLVST RDFIEDYVDI LRQAKQEFRE LKAEQHRKER
670 680 690 700 710 720
EEAAARIRKR KEEKLKEQEQ KMKEKQEKLK EDEQRNSTAD ISIGEEERED FDTSIESKDT
730 740 750 760 770 780
EQKELDQDMV TEDEDDPGSH KRGRRGKRGQ NGFKEFTRQE QINCVTREPL TADEEEALKQ
790 800 810 820 830 840
EHQRKEKELL EKIQSAIACT NIFPLGRDRM YRRYWIFPSI PGLFIEEDYS GLTEDMLLPR
850 860 870 880 890 900
PSSFQNNVQS QDPQVSTKTG EPLMSESTSN IDQGPRDHSV QLPKPVHKPN RWCFYSSCEQ
910 920 930 940 950 960
LDQLIEALNS RGHRESALKE TLLQEKSRIC AQLARFSEEK FHFSDKPQPD SKPTYSRGRS
970 980 990 1000 1010 1020
SNAYDPSQMC AEKQLELRLR DFLLDIEDRI YQGTLGAIKV TDRHIWRSAL ESGRYELLSE
1030 1040 1050 1060 1070 1080
ENKENGIIKT VNEDVEEMEI DEQTKVIVKD RLLGIKTETP STVSTNASTP QSVSSVVHYL
1090 1100 1110 1120 1130 1140
AMALFQIEQG IERRFLKAPL DASDSGRSYK TVLDRWRESL LSSASLSQVF LHLSTLDRSV
1150 1160 1170 1180 1190 1200
IWSKSILNAR CKICRKKGDA ENMVLCDGCD RGHHTYCVRP KLKTVPEGDW FCPECRPKQR
1210 1220 1230 1240 1250 1260
SRRLSSRQRP SLESDEDVED SMGGEDDEVD GDEEEGQSEE EEYEVEQDED DSQEEEEVSL
1270 1280 1290 1300 1310 1320
PKRGRPQVRL PVKTRGKLSS SFSSRGQQQE PGRYPSRSQQ STPKTTVSSK TGRSLRKINS
1330 1340 1350 1360 1370 1380
APPTETKSLR IASRSTRHSH GPLQADVFVE LLSPRRKRRG RKSANNTPEN SPNFPNFRVI
1390 1400 1410 1420 1430 1440
ATKSSEQSRS VNIASKLSLQ ESESKRRCRK RQSPEPSPVT LGRRSSGRQG GVHELSAFEQ
1450 1460 1470 1480 1490 1500
LVVELVRHDD SWPFLKLVSK IQVPDYYDII KKPIALNIIR EKVNKCEYKL ASEFIDDIEL
1510 1520 1530 1540 1550
MFSNCFEYNP RNTSEAKAGT RLQAFFHIQA QKLGLHVTPS NVDQVSTPPA AKKSRI
Isoforms
- Isoform 2 of Bromodomain adjacent to zinc finger domain protein 1ASequence View
10 20 30 40 50 60
MPLLHRKPFV RQKPPADLRP DEEVFYCKVT NEIFRHYDDF FERTILCNSL VWSCAVTGRP
70 80 90 100 110 120
GLTYQEALES EKKARQNLQS FPEPLIIPVL YLTSLTHRSR LHEICDDIFA YVKDRYFVEE
130 140 150 160 170 180
TVEVIRNNGA RLQCRILEVL PPSHQNGFAN GHVNSVDGET IIISDSDDSE TQSCSFQNGK
190 200 210 220 230 240
KKDAIDPLLF KYKVQPTKKE LHESAIVKAT QISRRKHLFS RDKLKLFLKQ HCEPQDGVIK
250 260 270 280 290 300
IKASSLSTYK IAEQDFSYFF PDDPPTFIFS PANRRRGRPP KRIHISQEDN VANKQTLASY
310 320 330 340 350 360
RSKATKERDK LLKQEEMKSL AFEKAKLKRE KADALEAKKK EKEDKEKKRE ELKKIVEEER
370 380 390 400 410 420
LKKKEEKERL KVEREKEREK LREEKRKYVE YLKQWSKPRE DMECDDLKEL PEPTPVKTRL
430 440 450 460 470 480
PPEIFGDALM VLEFLNAFGE LFDLQDEFPD GVTLEVLEEA LVGNDSEGPL CELLFFFLTA
490 500 510 520 530 540
IFQAIAEEEE EVAKEQLTDA DTKDLTEALD EDADPTKSAL SAVASLAAAW PQLHQGCSLK
550 560 570 580 590 600
SLDLDSCTLS EILRLHILAS GADVTSANAK YRYQKRGGFD ATDDACMELR LSNPSLVKKL
610 620 630 640 650 660
SSTSVYDLTP GEKMKILHAL CGKLLTLVST RDFIEDYVDI LRQAKQEFRE LKAEQHRKER
670 680 690 700 710 720
EEAAARIRKR KEEKLKEQEQ KMKEKQEKLK EDEQRNSTAD ISIGEEERED FDTSIESKDT
730 740 750 760 770 780
EQKELDQDMV TEDEDDPGSH KRGRRGKRGQ NGFKEFTRQE QINCVTREPL TADEEEALKQ
790 800 810 820 830 840
EHQRKEKELL EKIQSAIACT NIFPLGRDRM YRRYWIFPSI PGLFIEEDYS GLTEDMLLPR
850 860 870 880 890 900
PSSFQNNVQS QDPQVSTKTG EPLMSESTSN IDQGPRDHSV QLPKPVHKPN RWCFYSSCEQ
910 920 930 940 950 960
LDQLIEALNS RGHRESALKE TLLQEKSRIC AQLARFSEEK FHFSDKPQPD SKPTYSRGRS
970 980 990 1000 1010 1020
SNAYDPSQMC AEKQLELRLR DFLLDIEDRI YQGTLGAIKV TDRHIWRSAL ESGRYELLSE
1030 1040 1050 1060 1070 1080
ENKENGIIKT VNEDVEEMEI DEQTKVIVKD RLLGIKTETP STVSTNASTP QSVSSVVHYL
1090 1100 1110 1120 1130 1140
AMALFQIEQG IERRFLKAPL DASDSGRSYK TVLDRWRESL LSSASLSQVF LHLSTLDRSV
1150 1160 1170 1180 1190 1200
IWSKSILNAR CKICRKKGDA ENMVLCDGCD RGHHTYCVRP KLKTVPEGDW FCPECRPKQR
1210 1220 1230 1240 1250 1260
SRRLSSRQRP SLESDEDVED SMGGEDDEVD GDEEEGQSEE EEYEVEQDED DSQEEEEVSL
1270 1280 1290 1300 1310 1320
PKRGRPQVRL PVKTRGKLSS SFSSRGQQQE PGRYPSRSQQ STPKTTVSSK TGRSLRKINS
1330 1340 1350 1360 1370 1380
APPTETKSLR IASRSTRHSH GPLQADVFVE LLSPRRKRRG RKSANNTPEN SPNFPNFRVI
1390 1400 1410 1420 1430 1440
ATKSSEQSRS VNIASKLSLQ ESESKRRCRK RQSPEPSPVT LGRRSSGRQG GVHELSAFEQ
1450 1460 1470 1480 1490 1500
LVVELVRHDD SWPFLKLVSK IQVPDYYDII KKPIALNIIR EKVNKCEYKL ASEFIDDIEL
1510 1520 1530 1540 1550
MFSNCFEYNP RNTSEAKAGT RLQAFFHIQA QKLGLHVTPS NVDQVSTPPA AKKSRI
Protein Neighborhood
Domains & Features
6 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9NRL2-1-unknown | MPLLHR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9NRL2-1-unknown | MPLLHR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68235 | |||
Q9NRL2-69-unknown | ESEKKA... | 69 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15030 | |||
Q9NRL2-69-unknown | ESEKKA... | 69 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt140558 | |||
Q9NRL2-321-unknown | AFEKAK... | 321 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15032 | |||
Q9NRL2-321-unknown | AFEKAK... | 321 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150367 | |||
Q9NRL2-500- | ADTKDL... | 500 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9NRL2-500- | ADTKDL... | 500 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9NRL2-771-unknown | TADEEE... | 771 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15034 | |||
Q9NRL2-771-unknown | TADEEE... | 771 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156214 | |||
Q9NRL2-1347-unknown | VFVELL... | 1347 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13394 | |||
Q9NRL2-1347-unknown | VFVELL... | 1347 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157921 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...YQEALE | 68 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15030 | |||
...YQEALE | 68 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt123691 | |||
...EMKSLA | 320 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15032 | |||
...EMKSLA | 320 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133764 | |||
...TREPLT | 770 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15034 | |||
...TREPLT | 770 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139679 | |||
...PLQADV | 1346 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13394 | |||
...PLQADV | 1346 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141416 | |||
...KKSRI | 1556 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KKSRI | 1556 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt63853 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 68 | EALE.|.ESEK | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAM_HUMAN | 320 | KSLA.|.AFEK | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAM_HUMAN | 770 | EPLT.|.TADE | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAB_HUMAN | 1346 | QADV.|.VFVE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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