Q7Z309: Protein FAM122B

General Information

Protein names	- Protein FAM122B
Gene names	FAM122B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z309

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein FAM122B - Isoform 3 of Protein FAM122B - Isoform 4 of Protein FAM122B - Isoform 5 of Protein FAM122B

Sequence View

        10         20         30         40         50         60
MAQEKMELDL EPDTSYGGTL RRSSSAPLIH GLSDLSQVFQ PYTLRTRRNS TTIMSRHSLE
        70         80         90        100        110        120
EGLDMVNRET AHEREMQTAM QISQSWDESL SLSDSDFDKP EKLYSPKRID FTPVSPAPSP
       130        140        150        160        170        180
TRGFGKMFVS SSGLPPSPVP SPRRFSRRSQ SPVKCIRPSV LGPLKRKGEM ETESQPKRLF
       190        200        210        220        230        240
QGTTNMLSPD AAQLSDLSSC SDILDGSSSS SGLSSDPLAK GSATAESPVA CSNSCSSFIL

MDDLSPK         10         20         30         40         50         60
MAQEKMELDL EPDTSYGGTL RRSSSAPLIH GLSDLSQVFQ PYTLRTRRNS TTIMSRHSLE
        70         80         90        100        110        120
EGLDMVNRET AHEREMQTAM QISQSWDESL SLSDSDFDKP EKLYSPKRID FTPVSPAPSP
       130        140        150        160        170        180
TRGFGKMFVS SSGLPPSPVP SPRRFSRRSQ SPVKCIRPSV LGPLKRKGEM ETESQPKRLF
       190        200        210        220        230        240
QGTTNMLSPD AAQLSDLSSC SDILDGSSSS SGLSSDPLAK GSATAESPVA CSNSCSSFIL

MDDLSPK         10         20         30         40         50         60
MAQEKMELDL EPDTSYGGTL RRSSSAPLIH GLSDLSQVFQ PYTLRTRRNS TTIMSRHSLE
        70         80         90        100        110        120
EGLDMVNRET AHEREMQTAM QISQSWDESL SLSDSDFDKP EKLYSPKRID FTPVSPAPSP
       130        140        150        160        170        180
TRGFGKMFVS SSGLPPSPVP SPRRFSRRSQ SPVKCIRPSV LGPLKRKGEM ETESQPKRLF
       190        200        210        220        230        240
QGTTNMLSPD AAQLSDLSSC SDILDGSSSS SGLSSDPLAK GSATAESPVA CSNSCSSFIL

MDDLSPK         10         20         30         40         50         60
MAQEKMELDL EPDTSYGGTL RRSSSAPLIH GLSDLSQVFQ PYTLRTRRNS TTIMSRHSLE
        70         80         90        100        110        120
EGLDMVNRET AHEREMQTAM QISQSWDESL SLSDSDFDKP EKLYSPKRID FTPVSPAPSP
       130        140        150        160        170        180
TRGFGKMFVS SSGLPPSPVP SPRRFSRRSQ SPVKCIRPSV LGPLKRKGEM ETESQPKRLF
       190        200        210        220        230        240
QGTTNMLSPD AAQLSDLSSC SDILDGSSSS SGLSSDPLAK GSATAESPVA CSNSCSSFIL

MDDLSPK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z309-1-unknown	MAQEKM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74405
Q7Z309-1-unknown	MAQEKM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74406
Q7Z309-1-unknown	MAQEKM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74407
Q7Z309-2-unknown	MAQEKM...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110887
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110888
Q7Z309-2-Acetylation	AQEKME...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110889
Q7Z309-54-unknown	MSRHSL...	54		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74408
Q7Z309-54-unknown	MSRHSL...	54		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105236
Q7Z309-191-unknown	AAQLSD...	191		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12674
Q7Z309-191-unknown	AAQLSD...	191		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146318
Q7Z309-191-unknown	AAQLSD...	191		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146955

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MLSPDA	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12674
...MLSPDA	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129621
...MLSPDA	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130287
...MLSPDA	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155525
...MLSPDA	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155526
...DLSPK	247	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DLSPK	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70023
...DLSPK	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70024

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	190	SPDA.\|.AAQL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)