TopFIND 4.0

O95678: Keratin, type II cytoskeletal 75

General Information

Protein names
- Keratin, type II cytoskeletal 75
- Cytokeratin-75
- CK-75
- Keratin-6 hair follicle
- hK6hf
- Keratin-75
- K75
- Type II keratin-K6hf
- Type-II keratin Kb18
Gene names KRT75
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95678

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRQSSITFQ SGSRRGFSTT SAITPAAGRS RFSSVSVARS AAGSGGLGRI SSAGASFGSR 
        70         80         90        100        110        120 
SLYNLGGAKR VSINGCGSSC RSGFGGRASN RFGVNSGFGY GGGVGGGFSG PSFPVCPPGG 
       130        140        150        160        170        180 
IQEVTVNQSL LTPLHLQIDP TIQRVRAEER EQIKTLNNKF ASFIDKVRFL EQQNKVLETK 
       190        200        210        220        230        240 
WALLQEQGSR TVRQNLEPLF DSYTSELRRQ LESITTERGR LEAELRNMQD VVEDFKVRYE 
       250        260        270        280        290        300 
DEINKRTAAE NEFVALKKDV DAAYMNKVEL EAKVKSLPEE INFIHSVFDA ELSQLQTQVG 
       310        320        330        340        350        360 
DTSVVLSMDN NRNLDLDSII AEVKAQYEDI ANRSRAEAES WYQTKYEELQ VTAGRHGDDL 
       370        380        390        400        410        420 
RNTKQEISEM NRMIQRLRAE IDSVKKQCSS LQTAIADAEQ RGELALKDAR AKLVDLEEAL 
       430        440        450        460        470        480 
QKAKQDMARL LREYQELMNI KLALDVEIAT YRKLLEGEEC RLSGEGVSPV NISVVTSTLS 
       490        500        510        520        530        540 
SGYGSGSSIG GGNLGLGGGS GYSFTTSGGH SLGAGLGGSG FSATSNRGLG GSGSSVKFVS 
       550    
TTSSSQKSYT H

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O95678-1-unknown MSRQSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O95678-318-unknown SIIAEV... 318 inferred from cleavage unknown TopFIND Inferred from cleavage TC11028

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)