P50453: Serpin B9

General Information

Protein names	- Serpin B9 - Cytoplasmic antiproteinase 3 - CAP-3 - CAP3 - Peptidase inhibitor 9 - PI-9
Gene names	SERPINB9
Organism	Homo sapiens
Protease Family
Protease ID	I04.014
Chromosome location
UniProt ID	P50453

3 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
METLSNASGT FAIRLLKILC QDNPSHNVFC SPVSISSALA MVLLGAKGNT ATQMAQALSL
        70         80         90        100        110        120
NTEEDIHRAF QSLLTEVNKA GTQYLLRTAN RLFGEKTCQF LSTFKESCLQ FYHAELKELS
       130        140        150        160        170        180
FIRAAEESRK HINTWVSKKT EGKIEELLPG SSIDAETRLV LVNAIYFKGK WNEPFDETYT
       190        200        210        220        230        240
REMPFKINQE EQRPVQMMYQ EATFKLAHVG EVRAQLLELP YARKELSLLV LLPDDGVELS
       250        260        270        280        290        300
TVEKSLTFEK LTAWTKPDCM KSTEVEVLLP KFKLQEDYDM ESVLRHLGIV DAFQQGKADL
       310        320        330        340        350        360
SAMSAERDLC LSKFVHKSFV EVNEEGTEAA AASSCFVVAE CCMESGPRFC ADHPFLFFIR
       370
HNRANSILFC GRFSSP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P50453-1-Acetylation	METLSN...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P50453-1-Acetylation	METLSN...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P50453-1-Acetylation	METLSN...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P50453-1-Acetylation	METLSN...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P50453-341-unknown	CCMESG...	341		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11614
P50453-341-unknown	CCMESG...	341		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14179
P50453-343-unknown	MESGPR...	343		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9454

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FVVAEC	340	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11614
...FVVAEC	340	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14179
...VAECCM	342	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9454
...RFSSP	376	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	340	VAEC.\|.CCME	inferred from experiment	unknown	MEROPS	Craik CS	Mahrus S et al.:Granzyme M is a regulatory prot... (S01.131)	15494398,
GRAM_HUMAN	340	VAEC.\|.CCME	inferred from experiment	unknown	MEROPS	Craik CS	Mahrus S et al.:Granzyme M is a regulatory prot... (S01.131)	15494398,
ELNE_HUMAN	342	ECCM.\|.MESG	inferred from experiment	unknown	MEROPS	Craik CS	Mahrus S et al.:Granzyme M is a regulatory prot... (S01.131)	15494398,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)