Q9UF33: Ephrin type-A receptor 6
Protein names | - Ephrin type-A receptor 6 - 2.7.10.1 - EPH homology kinase 2 - EHK-2 - EPH-like kinase 12 - EK12 |
---|---|
Gene names | EPHA6 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9UF33 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGGCEVREFL LQFGFFLPLL TAWPGDCSHV SNNQVVLLDT TTVLGELGWK TYPLNGWDAI
70 80 90 100 110 120
TEMDEHNRPI HTYQVCNVME PNQNNWLRTN WISRDAAQKI YVEMKFTLRD CNSIPWVLGT
130 140 150 160 170 180
CKETFNLFYM ESDESHGIKF KPNQYTKIDT IAADESFTQM DLGDRILKLN TEIREVGPIE
190 200 210 220 230 240
RKGFYLAFQD IGACIALVSV RVFYKKCPFT VRNLAMFPDT IPRVDSSSLV EVRGSCVKSA
250 260 270 280 290 300
EERDTPKLYC GADGDWLVPL GRCICSTGYE EIEGSCHACR PGFYKAFAGN TKCSKCPPHS
310 320 330 340 350 360
LTYMEATSVC QCEKGYFRAE KDPPSMACTR PPSAPRNVVF NINETALILE WSPPSDTGGR
370 380 390 400 410 420
KDLTYSVICK KCGLDTSQCE DCGGGLRFIP RHTGLINNSV IVLDFVSHVN YTFEIEAMNG
430 440 450 460 470 480
VSELSFSPKP FTAITVTTDQ DAPSLIGVVR KDWASQNSIA LSWQAPAFSN GAILDYEIKY
490 500 510 520 530 540
YEKEHEQLTY SSTRSKAPSV IITGLKPATK YVFHIRVRTA TGYSGYSQKF EFETGDETSD
550 560 570 580 590 600
MAAEQGQILV IATAAVGGFT LLVILTLFFL ITGRCQWYIK AKMKSEEKRR NHLQNGHLRF
610 620 630 640 650 660
PGIKTYIDPD TYEDPSLAVH EFAKEIDPSR IRIERVIGAG EFGEVCSGRL KTPGKREIPV
670 680 690 700 710 720
AIKTLKGGHM DRQRRDFLRE ASIMGQFDHP NIIRLEGVVT KRSFPAIGVE AFCPSFLRAG
730 740 750 760 770 780
FLNSIQAPHP VPGGGSLPPR IPAGRPVMIV VEYMENGSLD SFLRKHDGHF TVIQLVGMLR
790 800 810 820 830 840
GIASGMKYLS DMGYVHRDLA ARNILVNSNL VCKVSDFGLS RVLEDDPEAA YTTTGGKIPI
850 860 870 880 890 900
RWTAPEAIAY RKFSSASDAW SYGIVMWEVM SYGERPYWEM SNQDVILSIE EGYRLPAPMG
910 920 930 940 950 960
CPASLHQLML HCWQKERNHR PKFTDIVSFL DKLIRNPSAL HTLVEDILVM PESPGEVPEY
970 980 990 1000 1010 1020
PLFVTVGDWL DSIKMGQYKN NFVAAGFTTF DLISRMSIDD IRRIGVILIG HQRRIVSSIQ
1030
TLRLHMMHIQ EKGFHV
Isoforms
- Isoform 2 of Ephrin type-A receptor 6 - Isoform 3 of Ephrin type-A receptor 6Sequence View
10 20 30 40 50 60
MGGCEVREFL LQFGFFLPLL TAWPGDCSHV SNNQVVLLDT TTVLGELGWK TYPLNGWDAI
70 80 90 100 110 120
TEMDEHNRPI HTYQVCNVME PNQNNWLRTN WISRDAAQKI YVEMKFTLRD CNSIPWVLGT
130 140 150 160 170 180
CKETFNLFYM ESDESHGIKF KPNQYTKIDT IAADESFTQM DLGDRILKLN TEIREVGPIE
190 200 210 220 230 240
RKGFYLAFQD IGACIALVSV RVFYKKCPFT VRNLAMFPDT IPRVDSSSLV EVRGSCVKSA
250 260 270 280 290 300
EERDTPKLYC GADGDWLVPL GRCICSTGYE EIEGSCHACR PGFYKAFAGN TKCSKCPPHS
310 320 330 340 350 360
LTYMEATSVC QCEKGYFRAE KDPPSMACTR PPSAPRNVVF NINETALILE WSPPSDTGGR
370 380 390 400 410 420
KDLTYSVICK KCGLDTSQCE DCGGGLRFIP RHTGLINNSV IVLDFVSHVN YTFEIEAMNG
430 440 450 460 470 480
VSELSFSPKP FTAITVTTDQ DAPSLIGVVR KDWASQNSIA LSWQAPAFSN GAILDYEIKY
490 500 510 520 530 540
YEKEHEQLTY SSTRSKAPSV IITGLKPATK YVFHIRVRTA TGYSGYSQKF EFETGDETSD
550 560 570 580 590 600
MAAEQGQILV IATAAVGGFT LLVILTLFFL ITGRCQWYIK AKMKSEEKRR NHLQNGHLRF
610 620 630 640 650 660
PGIKTYIDPD TYEDPSLAVH EFAKEIDPSR IRIERVIGAG EFGEVCSGRL KTPGKREIPV
670 680 690 700 710 720
AIKTLKGGHM DRQRRDFLRE ASIMGQFDHP NIIRLEGVVT KRSFPAIGVE AFCPSFLRAG
730 740 750 760 770 780
FLNSIQAPHP VPGGGSLPPR IPAGRPVMIV VEYMENGSLD SFLRKHDGHF TVIQLVGMLR
790 800 810 820 830 840
GIASGMKYLS DMGYVHRDLA ARNILVNSNL VCKVSDFGLS RVLEDDPEAA YTTTGGKIPI
850 860 870 880 890 900
RWTAPEAIAY RKFSSASDAW SYGIVMWEVM SYGERPYWEM SNQDVILSIE EGYRLPAPMG
910 920 930 940 950 960
CPASLHQLML HCWQKERNHR PKFTDIVSFL DKLIRNPSAL HTLVEDILVM PESPGEVPEY
970 980 990 1000 1010 1020
PLFVTVGDWL DSIKMGQYKN NFVAAGFTTF DLISRMSIDD IRRIGVILIG HQRRIVSSIQ
1030
TLRLHMMHIQ EKGFHV
10 20 30 40 50 60
MGGCEVREFL LQFGFFLPLL TAWPGDCSHV SNNQVVLLDT TTVLGELGWK TYPLNGWDAI
70 80 90 100 110 120
TEMDEHNRPI HTYQVCNVME PNQNNWLRTN WISRDAAQKI YVEMKFTLRD CNSIPWVLGT
130 140 150 160 170 180
CKETFNLFYM ESDESHGIKF KPNQYTKIDT IAADESFTQM DLGDRILKLN TEIREVGPIE
190 200 210 220 230 240
RKGFYLAFQD IGACIALVSV RVFYKKCPFT VRNLAMFPDT IPRVDSSSLV EVRGSCVKSA
250 260 270 280 290 300
EERDTPKLYC GADGDWLVPL GRCICSTGYE EIEGSCHACR PGFYKAFAGN TKCSKCPPHS
310 320 330 340 350 360
LTYMEATSVC QCEKGYFRAE KDPPSMACTR PPSAPRNVVF NINETALILE WSPPSDTGGR
370 380 390 400 410 420
KDLTYSVICK KCGLDTSQCE DCGGGLRFIP RHTGLINNSV IVLDFVSHVN YTFEIEAMNG
430 440 450 460 470 480
VSELSFSPKP FTAITVTTDQ DAPSLIGVVR KDWASQNSIA LSWQAPAFSN GAILDYEIKY
490 500 510 520 530 540
YEKEHEQLTY SSTRSKAPSV IITGLKPATK YVFHIRVRTA TGYSGYSQKF EFETGDETSD
550 560 570 580 590 600
MAAEQGQILV IATAAVGGFT LLVILTLFFL ITGRCQWYIK AKMKSEEKRR NHLQNGHLRF
610 620 630 640 650 660
PGIKTYIDPD TYEDPSLAVH EFAKEIDPSR IRIERVIGAG EFGEVCSGRL KTPGKREIPV
670 680 690 700 710 720
AIKTLKGGHM DRQRRDFLRE ASIMGQFDHP NIIRLEGVVT KRSFPAIGVE AFCPSFLRAG
730 740 750 760 770 780
FLNSIQAPHP VPGGGSLPPR IPAGRPVMIV VEYMENGSLD SFLRKHDGHF TVIQLVGMLR
790 800 810 820 830 840
GIASGMKYLS DMGYVHRDLA ARNILVNSNL VCKVSDFGLS RVLEDDPEAA YTTTGGKIPI
850 860 870 880 890 900
RWTAPEAIAY RKFSSASDAW SYGIVMWEVM SYGERPYWEM SNQDVILSIE EGYRLPAPMG
910 920 930 940 950 960
CPASLHQLML HCWQKERNHR PKFTDIVSFL DKLIRNPSAL HTLVEDILVM PESPGEVPEY
970 980 990 1000 1010 1020
PLFVTVGDWL DSIKMGQYKN NFVAAGFTTF DLISRMSIDD IRRIGVILIG HQRRIVSSIQ
1030
TLRLHMMHIQ EKGFHV
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UF33-23-unknown | WPGDCS... | 23 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UF33-154-unknown | DESFTQ... | 154 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13513 | |||
Q9UF33-541-unknown | MAAEQG... | 541 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000403100 | |||
Q9UF33-541-unknown | MAAEQG... | 541 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt129311 | |||
Q9UF33-541-unknown | MAAEQG... | 541 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt129312 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...DTIAAD | 153 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13513 | |||
...KGFHV | 1036 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 153 | IAAD.|.DESF | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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