TopFIND 4.0

P22459: Potassium voltage-gated channel subfamily A member 4

General Information

Protein names
- Potassium voltage-gated channel subfamily A member 4
- HPCN2
- Voltage-gated K(+) channel HuKII {ECO:0000303|PubMed:19912772}
- Voltage-gated potassium channel HBK4
- Voltage-gated potassium channel HK1 {ECO:0000303|PubMed:2001794}
- Voltage-gated potassium channel subunit Kv1.4
Gene names KCNA4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P22459

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEVAMVSAES SGCNSHMPYG YAAQARARER ERLAHSRAAA AAAVAAATAA VEGSGGSGGG 
        70         80         90        100        110        120 
SHHHHQSRGA CTSHDPQSSR GSRRRRRQRS EKKKAHYRQS SFPHCSDLMP SGSEEKILRE 
       130        140        150        160        170        180 
LSEEEEDEEE EEEEEEEGRF YYSEDDHGDE CSYTDLLPQD EGGGGYSSVR YSDCCERVVI 
       190        200        210        220        230        240 
NVSGLRFETQ MKTLAQFPET LLGDPEKRTQ YFDPLRNEYF FDRNRPSFDA ILYYYQSGGR 
       250        260        270        280        290        300 
LKRPVNVPFD IFTEEVKFYQ LGEEALLKFR EDEGFVREEE DRALPENEFK KQIWLLFEYP 
       310        320        330        340        350        360 
ESSSPARGIA IVSVLVILIS IVIFCLETLP EFRDDRDLVM ALSAGGHGGL LNDTSAPHLE 
       370        380        390        400        410        420 
NSGHTIFNDP FFIVETVCIV WFSFEFVVRC FACPSQALFF KNIMNIIDIV SILPYFITLG 
       430        440        450        460        470        480 
TDLAQQQGGG NGQQQQAMSF AILRIIRLVR VFRIFKLSRH SKGLQILGHT LRASMRELGL 
       490        500        510        520        530        540 
LIFFLFIGVI LFSSAVYFAE ADEPTTHFQS IPDAFWWAVV TMTTVGYGDM KPITVGGKIV 
       550        560        570        580        590        600 
GSLCAIAGVL TIALPVPVIV SNFNYFYHRE TENEEQTQLT QNAVSCPYLP SNLLKKFRSS 
       610        620        630        640        650    
TSSSLGDKSE YLEMEEGVKE SLCAKEEKCQ GKGDDSETDK NNCSNAKAVE TDV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22459-1-unknown MEVAMV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22459-354-unknown TSAPHL... 354 inferred from cleavage unknown TopFIND Inferred from cleavage TC11341

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)