Q5SXM2: snRNA-activating protein complex subunit 4

General Information

Protein names	- snRNA-activating protein complex subunit 4 - SNAPc subunit 4 - Proximal sequence element-binding transcription factor subunit alpha - PSE-binding factor subunit alpha - PTF subunit alpha - snRNA-activating protein complex 190 kDa subunit - SNAPc 190 kDa subunit
Gene names	SNAPC4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5SXM2

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDVDAEREKI TQEIKELERI LDPGSSGSHV EISESSLESD SEADSLPSED LDPADPPISE
        70         80         90        100        110        120
EERWGEASND EDDPKDKTLP EDPETCLQLN MVYQEVIQEK LAEANLLLAQ NREQQEELMR
       130        140        150        160        170        180
DLAGSKGTKV KDGKSLPPST YMGHFMKPYF KDKVTGVGPP ANEDTREKAA QGIKAFEELL
       190        200        210        220        230        240
VTKWKNWEKA LLRKSVVSDR LQRLLQPKLL KLEYLHQKQS KVSSELERQA LEKQGREAEK
       250        260        270        280        290        300
EIQDINQLPE EALLGNRLDS HDWEKISNIN FEGSRSAEEI RKFWQNSEHP SINKQEWSRE
       310        320        330        340        350        360
EEERLQAIAA AHGHLEWQKI AEELGTSRSA FQCLQKFQQH NKALKRKEWT EEEDRMLTQL
       370        380        390        400        410        420
VQEMRVGSHI PYRRIVYYME GRDSMQLIYR WTKSLDPGLK KGYWAPEEDA KLLQAVAKYG
       430        440        450        460        470        480
EQDWFKIREE VPGRSDAQCR DRYLRRLHFS LKKGRWNLKE EEQLIELIEK YGVGHWAKIA
       490        500        510        520        530        540
SELPHRSGSQ CLSKWKIMMG KKQGLRRRRR RARHSVRWSS TSSSGSSSGS SGGSSSSSSS
       550        560        570        580        590        600
SSEEDEPEQA QAGEGDRALL SPQYMVPDMD LWVPARQSTS QPWRGGAGAW LGGPAASLSP
       610        620        630        640        650        660
PKGSSASQGG SKEASTTAAA PGEETSPVQV PARAHGPVPR SAQASHSADT RPAGAEKQAL
       670        680        690        700        710        720
EGGRRLLTVP VETVLRVLRA NTAARSCTQK EQLRQPPLPT SSPGVSSGDS VARSHVQWLR
       730        740        750        760        770        780
HRATQSGQRR WRHALHRRLL NRRLLLAVTP WVGDVVVPCT QASQRPAVVQ TQADGLREQL
       790        800        810        820        830        840
QQARLASTPV FTLFTQLFHI DTAGCLEVVR ERKALPPRLP QAGARDPPVH LLQASSSAQS
       850        860        870        880        890        900
TPGHLFPNVP AQEASKSASH KGSRRLASSR VERTLPQASL LASTGPRPKP KTVSELLQEK
       910        920        930        940        950        960
RLQEARAREA TRGPVVLPSQ LLVSSSVILQ PPLPHTPHGR PAPGPTVLNV PLSGPGAPAA
       970        980        990       1000       1010       1020
AKPGTSGSWQ EAGTSAKDKR LSTMQALPLA PVFSEAEGTA PAASQAPALG PGQISVSCPE
      1030       1040       1050       1060       1070       1080
SGLGQSQAPA ASRKQGLPEA PPFLPAAPSP TPLPVQPLSL THIGGPHVAT SVPLPVTWVL
      1090       1100       1110       1120       1130       1140
TAQGLLPVPV PAVVSLPRPA GTPGPAGLLA TLLPPLTETR AAQGPRAPAL SSSWQPPANM
      1150       1160       1170       1180       1190       1200
NREPEPSCRT DTPAPPTHAL SQSPAEADGS VAFVPGEAQV AREIPEPRTS SHADPPEAEP
      1210       1220       1230       1240       1250       1260
PWSGRLPAFG GVIPATEPRG TPGSPSGTQE PRGPLGLEKL PLRQPGPEKG ALDLEKPPLP
      1270       1280       1290       1300       1310       1320
QPGPEKGALD LGLLSQEGEA ATQQWLGGQR GVRVPLLGSR LPYQPPALCS LRALSGLLLH
      1330       1340       1350       1360       1370       1380
KKALEHKATS LVVGGEAERP AGALQASLGL VRGQLQDNPA YLLLRARFLA AFTLPALLAT
      1390       1400       1410       1420       1430       1440
LAPQGVRTTL SVPSRVGSES EDEDLLSELE LADRDGQPGC TTATCPIQGA PDSGKCSASS
      1450       1460
CLDTSNDPDD LDVLRTRHAR HTRKRRRLV

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q5SXM2-1-unknown	MDVDAE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q5SXM2-569-unknown	MDLWVP...	569	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12499
Q5SXM2-1169-	GSVAFV...	1169		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q5SXM2-1169-	GSVAFV...	1169		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YMVPDM	568	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12499
	...RRRLV	1469	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	568	VPDM.\|.MDLW	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)