Q969S3: Zinc finger protein 622

General Information

Protein names	- Zinc finger protein 622 - Zinc finger-like protein 9
Gene names	ZNF622
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q969S3

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATYTCITCR VAFRDADMQR AHYKTDWHRY NLRRKVASMA PVTAEGFQER VRAQRAVAEE
        70         80         90        100        110        120
ESKGSATYCT VCSKKFASFN AYENHLKSRR HVELEKKAVQ AVNRKVEMMN EKNLEKGLGV
       130        140        150        160        170        180
DSVDKDAMNA AIQQAIKAQP SMSPKKAPPA PAKEARNVVA VGTGGRGTHD RDPSEKPPRL
       190        200        210        220        230        240
QWFEQQAKKL AKQQEEDSEE EEEDLDGDDW EDIDSDEELE CEDTEAMDDV VEQDAEEEEA
       250        260        270        280        290        300
EEGPPLGAIP ITDCLFCSHH SSSLMKNVAH MTKDHSFFIP DIEYLSDIKG LIKYLGEKVG
       310        320        330        340        350        360
VGKICLWCNE KGKSFYSTEA VQAHMNDKSH CKLFTDGDAA LEFADFYDFR SSYPDHKEGE
       370        380        390        400        410        420
DPNKAEELPS EKNLEYDDET MELILPSGAR VGHRSLMRYY KQRFGLSRAV AVAKNRKAVG
       430        440        450        460        470
RVLQQYRALG WTGSTGAALM RERDMQYVQR MKSKWMLKTG MKNNATKQMH FRVQVRF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q969S3-2-unknown	MATYTC...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969S3-2-Acetylation	ATYTCI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969S3-2-Acetylation	ATYTCI...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q969S3-2-Acetylation	ATYTCI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q969S3-122-	SVDKDA...	122			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q969S3-127-unknown	AMNAAI...	127		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13038
Q969S3-129-unknown	NAAIQQ...	129		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14820

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SVDKDA	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13038
...DKDAMN	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14820
...VQVRF	477	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	126	DKDA.\|.AMNA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAM_HUMAN	128	DAMN.\|.NAAI	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)