P42263: Glutamate receptor 3
Protein names | - Glutamate receptor 3 - GluR-3 - AMPA-selective glutamate receptor 3 - GluR-C - GluR-K3 - Glutamate receptor ionotropic, AMPA 3 - GluA3 |
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Gene names | GRIA3 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P42263 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MARQKKMGQS VLRAVFFLVL GLLGHSHGGF PNTISIGGLF MRNTVQEHSA FRFAVQLYNT
70 80 90 100 110 120
NQNTTEKPFH LNYHVDHLDS SNSFSVTNAF CSQFSRGVYA IFGFYDQMSM NTLTSFCGAL
130 140 150 160 170 180
HTSFVTPSFP TDADVQFVIQ MRPALKGAIL SLLGHYKWEK FVYLYDTERG FSILQAIMEA
190 200 210 220 230 240
AVQNNWQVTA RSVGNIKDVQ EFRRIIEEMD RRQEKRYLID CEVERINTIL EQVVILGKHS
250 260 270 280 290 300
RGYHYMLANL GFTDILLERV MHGGANITGF QIVNNENPMV QQFIQRWVRL DEREFPEAKN
310 320 330 340 350 360
APLKYTSALT HDAILVIAEA FRYLRRQRVD VSRRGSAGDC LANPAVPWSQ GIDIERALKM
370 380 390 400 410 420
VQVQGMTGNI QFDTYGRRTN YTIDVYEMKV SGSRKAGYWN EYERFVPFSD QQISNDSASS
430 440 450 460 470 480
ENRTIVVTTI LESPYVMYKK NHEQLEGNER YEGYCVDLAY EIAKHVRIKY KLSIVGDGKY
490 500 510 520 530 540
GARDPETKIW NGMVGELVYG RADIAVAPLT ITLVREEVID FSKPFMSLGI SIMIKKPQKS
550 560 570 580 590 600
KPGVFSFLDP LAYEIWMCIV FAYIGVSVVL FLVSRFSPYE WHLEDNNEEP RDPQSPPDPP
610 620 630 640 650 660
NEFGIFNSLW FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER
670 680 690 700 710 720
MVSPIESAED LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWSYMKSAE PSVFTKTTAD
730 740 750 760 770 780
GVARVRKSKG KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSALRNAVNL
790 800 810 820 830 840
AVLKLNEQGL LDKLKNKWWY DKGECGSGGG DSKDKTSALS LSNVAGVFYI LVGGLGLAMM
850 860 870 880 890
VALIEFCYKS RAESKRMKLT KNTQNFKPAP ATNTQNYATY REGYNVYGTE SVKI
Isoforms
- Isoform Flip of Glutamate receptor 3Sequence View
10 20 30 40 50 60
MARQKKMGQS VLRAVFFLVL GLLGHSHGGF PNTISIGGLF MRNTVQEHSA FRFAVQLYNT
70 80 90 100 110 120
NQNTTEKPFH LNYHVDHLDS SNSFSVTNAF CSQFSRGVYA IFGFYDQMSM NTLTSFCGAL
130 140 150 160 170 180
HTSFVTPSFP TDADVQFVIQ MRPALKGAIL SLLGHYKWEK FVYLYDTERG FSILQAIMEA
190 200 210 220 230 240
AVQNNWQVTA RSVGNIKDVQ EFRRIIEEMD RRQEKRYLID CEVERINTIL EQVVILGKHS
250 260 270 280 290 300
RGYHYMLANL GFTDILLERV MHGGANITGF QIVNNENPMV QQFIQRWVRL DEREFPEAKN
310 320 330 340 350 360
APLKYTSALT HDAILVIAEA FRYLRRQRVD VSRRGSAGDC LANPAVPWSQ GIDIERALKM
370 380 390 400 410 420
VQVQGMTGNI QFDTYGRRTN YTIDVYEMKV SGSRKAGYWN EYERFVPFSD QQISNDSASS
430 440 450 460 470 480
ENRTIVVTTI LESPYVMYKK NHEQLEGNER YEGYCVDLAY EIAKHVRIKY KLSIVGDGKY
490 500 510 520 530 540
GARDPETKIW NGMVGELVYG RADIAVAPLT ITLVREEVID FSKPFMSLGI SIMIKKPQKS
550 560 570 580 590 600
KPGVFSFLDP LAYEIWMCIV FAYIGVSVVL FLVSRFSPYE WHLEDNNEEP RDPQSPPDPP
610 620 630 640 650 660
NEFGIFNSLW FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER
670 680 690 700 710 720
MVSPIESAED LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWSYMKSAE PSVFTKTTAD
730 740 750 760 770 780
GVARVRKSKG KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSALRNAVNL
790 800 810 820 830 840
AVLKLNEQGL LDKLKNKWWY DKGECGSGGG DSKDKTSALS LSNVAGVFYI LVGGLGLAMM
850 860 870 880 890
VALIEFCYKS RAESKRMKLT KNTQNFKPAP ATNTQNYATY REGYNVYGTE SVKI
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P42263-1-unknown | MARQKK... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76441 | |||
P42263-29-unknown | GFPNTI... | 29 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P42263-29-unknown | GFPNTI... | 29 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt114471 | |||
P42263-417-unknown | SASSEN... | 417 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11513 | |||
P42263-417-unknown | SASSEN... | 417 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152292 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QISNDS | 416 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11513 | |||
...QISNDS | 416 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135702 | |||
...ESVKI | 894 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...ESVKI | 894 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72059 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 416 | SNDS.|.SASS | inferred from experiment | unknown | MEROPS | Rogers SW | Gahring L et al.:Granzyme B proteolysis of a neu... (S01.010) | 11160179, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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