O75145: Liprin-alpha-3

General Information

Protein names	- Liprin-alpha-3 - Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3 - PTPRF-interacting protein alpha-3
Gene names	PPFIA3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75145

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMCEVMPTIS EDGRRGSALG PDEAGGELER LMVTMLTERE RLLETLREAQ DGLATAQLRL
        70         80         90        100        110        120
RELGHEKDSL QRQLSIALPQ EFAALTKELN LCREQLLERE EEIAELKAER NNTRLLLEHL
       130        140        150        160        170        180
ECLVSRHERS LRMTVVKRQA QSPGGVSSEV EVLKALKSLF EHHKALDEKV RERLRMALER
       190        200        210        220        230        240
VAVLEEELEL SNQETLNLRE QLSRRRSGLE EPGKDGDGQT LANGLGPGGD SNRRTAELEE
       250        260        270        280        290        300
ALERQRAEVC QLRERLAVLC RQMSQLEEEL GTAHRELGKA EEANSKLQRD LKEALAQRED
       310        320        330        340        350        360
MEERITTLEK RYLSAQREAT SLHDANDKLE NELASKESLY RQSEEKSRQL AEWLDDAKQK
       370        380        390        400        410        420
LQQTLQKAET LPEIEAQLAQ RVAALNKAEE RHGNFEERLR QLEAQLEEKN QELQRARQRE
       430        440        450        460        470        480
KMNDDHNKRL SETVDKLLSE SNERLQLHLK ERMGALEEKN SLSEEIANMK KLQDELLLNK
       490        500        510        520        530        540
EQLLAEMERM QMEIDQLRGR PPSSYSRSLP GSALELRYSQ APTLPSGAHL DPYVAGSGRA
       550        560        570        580        590        600
GKRGRWSGVK EEPSKDWERS APAGSIPPPF PGELDGSDEE EAEGMFGAEL LSPSGQADVQ
       610        620        630        640        650        660
TLAIMLQEQL EAINKEIKLI QEEKETTEQR AEELESRVSS SGLDSLGRYR SSCSLPPSLT
       670        680        690        700        710        720
TSTLASPSPP SSGHSTPRLA PPSPAREGTD KANHVPKEEA GAPRGEGPAI PGDTPPPTPR
       730        740        750        760        770        780
SARLERMTQA LALQAGSLED GGPPRGSEGT PDSLHKAPKK KSIKSSIGRL FGKKEKGRMG
       790        800        810        820        830        840
PPGRDSSSLA GTPSDETLAT DPLGLAKLTG PGDKDRRNKR KHELLEEACR QGLPFAAWDG
       850        860        870        880        890        900
PTVVSWLELW VGMPAWYVAA CRANVKSGAI MANLSDTEIQ REIGISNPLH RLKLRLAIQE
       910        920        930        940        950        960
MVSLTSPSAP ASSRTSTGNV WMTHEEMESL TATTKPETKE ISWEQILAYG DMNHEWVGND
       970        980        990       1000       1010       1020
WLPSLGLPQY RSYFMESLVD ARMLDHLNKK ELRGQLKMVD SFHRVSLHYG IMCLKRLNYD
      1030       1040       1050       1060       1070       1080
RKDLERRREE SQTQIRDVMV WSNERVMGWV SGLGLKEFAT NLTESGVHGA LLALDETFDY
      1090       1100       1110       1120       1130       1140
SDLALLLQIP TQNAQARQLL EKEFSNLISL GTDRRLDEDS AKSFSRSPSW RKMFREKDLR
      1150       1160       1170       1180       1190
GVTPDSAEML PPNFRSAAAG ALGSPGLPLR KLQPEGQTSG SSRADGVSVR TYSC

Isoforms

- Isoform 2 of Liprin-alpha-3

Sequence View

        10         20         30         40         50         60
MMCEVMPTIS EDGRRGSALG PDEAGGELER LMVTMLTERE RLLETLREAQ DGLATAQLRL
        70         80         90        100        110        120
RELGHEKDSL QRQLSIALPQ EFAALTKELN LCREQLLERE EEIAELKAER NNTRLLLEHL
       130        140        150        160        170        180
ECLVSRHERS LRMTVVKRQA QSPGGVSSEV EVLKALKSLF EHHKALDEKV RERLRMALER
       190        200        210        220        230        240
VAVLEEELEL SNQETLNLRE QLSRRRSGLE EPGKDGDGQT LANGLGPGGD SNRRTAELEE
       250        260        270        280        290        300
ALERQRAEVC QLRERLAVLC RQMSQLEEEL GTAHRELGKA EEANSKLQRD LKEALAQRED
       310        320        330        340        350        360
MEERITTLEK RYLSAQREAT SLHDANDKLE NELASKESLY RQSEEKSRQL AEWLDDAKQK
       370        380        390        400        410        420
LQQTLQKAET LPEIEAQLAQ RVAALNKAEE RHGNFEERLR QLEAQLEEKN QELQRARQRE
       430        440        450        460        470        480
KMNDDHNKRL SETVDKLLSE SNERLQLHLK ERMGALEEKN SLSEEIANMK KLQDELLLNK
       490        500        510        520        530        540
EQLLAEMERM QMEIDQLRGR PPSSYSRSLP GSALELRYSQ APTLPSGAHL DPYVAGSGRA
       550        560        570        580        590        600
GKRGRWSGVK EEPSKDWERS APAGSIPPPF PGELDGSDEE EAEGMFGAEL LSPSGQADVQ
       610        620        630        640        650        660
TLAIMLQEQL EAINKEIKLI QEEKETTEQR AEELESRVSS SGLDSLGRYR SSCSLPPSLT
       670        680        690        700        710        720
TSTLASPSPP SSGHSTPRLA PPSPAREGTD KANHVPKEEA GAPRGEGPAI PGDTPPPTPR
       730        740        750        760        770        780
SARLERMTQA LALQAGSLED GGPPRGSEGT PDSLHKAPKK KSIKSSIGRL FGKKEKGRMG
       790        800        810        820        830        840
PPGRDSSSLA GTPSDETLAT DPLGLAKLTG PGDKDRRNKR KHELLEEACR QGLPFAAWDG
       850        860        870        880        890        900
PTVVSWLELW VGMPAWYVAA CRANVKSGAI MANLSDTEIQ REIGISNPLH RLKLRLAIQE
       910        920        930        940        950        960
MVSLTSPSAP ASSRTSTGNV WMTHEEMESL TATTKPETKE ISWEQILAYG DMNHEWVGND
       970        980        990       1000       1010       1020
WLPSLGLPQY RSYFMESLVD ARMLDHLNKK ELRGQLKMVD SFHRVSLHYG IMCLKRLNYD
      1030       1040       1050       1060       1070       1080
RKDLERRREE SQTQIRDVMV WSNERVMGWV SGLGLKEFAT NLTESGVHGA LLALDETFDY
      1090       1100       1110       1120       1130       1140
SDLALLLQIP TQNAQARQLL EKEFSNLISL GTDRRLDEDS AKSFSRSPSW RKMFREKDLR
      1150       1160       1170       1180       1190
GVTPDSAEML PPNFRSAAAG ALGSPGLPLR KLQPEGQTSG SSRADGVSVR TYSC

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75145-1-unknown	MMCEVM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75145-1-unknown	MMCEVM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79635
O75145-821-unknown	KHELLE...	821	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18297
O75145-821-unknown	KHELLE...	821	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156569
O75145-909-unknown	APASSR...	909	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473418
O75145-909-unknown	APASSR...	909	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200434
O75145-952-unknown	MNHEWV...	952	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473423
O75145-952-unknown	MNHEWV...	952	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200467
O75145-1038-unknown	VMVWSN...	1038	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10905
O75145-1038-unknown	VMVWSN...	1038	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157224

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SPGGVS	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473621
...SPGGVS	146	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154917
...RRNKRK	820	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18297
...RRNKRK	820	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140053
...TQIRDV	1037	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10905
...TQIRDV	1037	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140723
...RTYSC	1194	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RTYSC	1194	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75253

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	820	NKRK.\|.KHEL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	1037	IRDV.\|.VMVW	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

TopFIND

O75145: Liprin-alpha-3

General Information

5

N-termini

4

C-termini

2

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates