Q92539: Phosphatidate phosphatase LPIN2

General Information

Protein names	- Phosphatidate phosphatase LPIN2 - 3.1.3.4 - Lipin-2
Gene names	LPIN2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92539

2 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNYVGQLAGQ VIVTVKELYK GINQATLSGC IDVIVVQQQD GSYQCSPFHV RFGKLGVLRS
        70         80         90        100        110        120
KEKVIDIEIN GSAVDLHMKL GDNGEAFFVE ETEEEYEKLP AYLATSPIPT EDQFFKDIDT
       130        140        150        160        170        180
PLVKSGGDET PSQSSDISHV LETETIFTPS SVKKKKRRRK KYKQDSKKEE QAASAAAEDT
       190        200        210        220        230        240
CDVGVSSDDD KGAQAARGSS NASLKEEECK EPLLFHSGDH YPLSDGDWSP LETTYPQTAC
       250        260        270        280        290        300
PKSDSELEVK PAESLLRSES HMEWTWGGFP ESTKVSKRER SDHHPRTATI TPSENTHFRV
       310        320        330        340        350        360
IPSEDNLISE VEKDASMEDT VCTIVKPKPR ALGTQMSDPT SVAELLEPPL ESTQISSMLD
       370        380        390        400        410        420
ADHLPNAALA EAPSESKPAA KVDSPSKKKG VHKRSQHQGP DDIYLDDLKG LEPEVAALYF
       430        440        450        460        470        480
PKSESEPGSR QWPESDTLSG SQSPQSVGSA AADSGTECLS DSAMDLPDVT LSLCGGLSEN
       490        500        510        520        530        540
GEISKEKFME HIITYHEFAE NPGLIDNPNL VIRIYNRYYN WALAAPMILS LQVFQKSLPK
       550        560        570        580        590        600
ATVESWVKDK MPKKSGRWWF WRKRESMTKQ LPESKEGKSE APPASDLPSS SKEPAGARPA
       610        620        630        640        650        660
ENDSSSDEGS QELEESITVD PIPTEPLSHG STTSYKKSLR LSSDQIAKLK LHDGPNDVVF
       670        680        690        700        710        720
SITTQYQGTC RCAGTIYLWN WNDKIIISDI DGTITKSDAL GQILPQLGKD WTHQGIAKLY
       730        740        750        760        770        780
HSINENGYKF LYCSARAIGM ADMTRGYLHW VNDKGTILPR GPLMLSPSSL FSAFHREVIE
       790        800        810        820        830        840
KKPEKFKIEC LNDIKNLFAP SKQPFYAAFG NRPNDVYAYT QVGVPDCRIF TVNPKGELIQ
       850        860        870        880        890
ERTKGNKSSY HRLSELVEHV FPLLSKEQNS AFPCPEFSSF CYWRDPIPEV DLDDLS

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92539-1-unknown	MNYVGQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92539-189-unknown	DDKGAQ...	189		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12992

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FVEETE	92	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463810
...GVSSDD	188	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12992
...WSPLET	232	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463026
...LDDLS	896	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	188	SSDD.\|.DDKG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)