P57737: Coronin-7

General Information

Protein names	- Coronin-7 - Crn7 - 70 kDa WD repeat tumor rejection antigen homolog
Gene names	CORO7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P57737

8 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Coronin-7 - Isoform 3 of Coronin-7 - Isoform 4 of Coronin-7

Sequence View

        10         20         30         40         50         60
MNRFRVSKFR HTEARPPRRE SWISDIRAGT APSCRNHIKS SCSLIAFNSD RPGVLGIVPL
        70         80         90        100        110        120
QGQGEDKRRV AHLGCHSDLV TDLDFSPFDD FLLATGSADR TVKLWRLPGP GQALPSAPGV
       130        140        150        160        170        180
VLGPEDLPVE VLQFHPTSDG ILVSAAGTTV KVWDAAKQQP LTELAAHGDL VQSAVWSRDG
       190        200        210        220        230        240
ALVGTACKDK QLRIFDPRTK PRASQSTQAH ENSRDSRLAW MGTWEHLVST GFNQMREREV
       250        260        270        280        290        300
KLWDTRFFSS ALASLTLDTS LGCLVPLLDP DSGLLVLAGK GERQLYCYEV VPQQPALSPV
       310        320        330        340        350        360
TQCVLESVLR GAALVPRQAL AVMSCEVLRV LQLSDTAIVP IGYHVPRKAV EFHEDLFPDT
       370        380        390        400        410        420
AGCVPATDPH SWWAGDNQQV QKVSLNPACR PHPSFTSCLV PPAEPLPDTA QPAVMETPVG
       430        440        450        460        470        480
DADASEGFSS PPSSLTSPST PSSLGPSLSS TSGIGTSPSL RSLQSLLGPS SKFRHAQGTV
       490        500        510        520        530        540
LHRDSHITNL KGLNLTTPGE SDGFCANKLR VAVPLLSSGG QVAVLELRKP GRLPDTALPT
       550        560        570        580        590        600
LQNGAAVTDL AWDPFDPHRL AVAGEDARIR LWRVPAEGLE EVLTTPETVL TGHTEKICSL
       610        620        630        640        650        660
RFHPLAANVL ASSSYDLTVR IWDLQAGADR LKLQGHQDQI FSLAWSPDGQ QLATVCKDGR
       670        680        690        700        710        720
VRVYRPRSGP EPLQEGPGPK GGRGARIVWV CDGRCLLVSG FDSQSERQLL LYEAEALAGG
       730        740        750        760        770        780
PLAVLGLDVA PSTLLPSYDP DTGLVLLTGK GDTRVFLYEL LPESPFFLEC NSFTSPDPHK
       790        800        810        820        830        840
GLVLLPKTEC DVREVELMRC LRLRQSSLEP VAFRLPRVRK EFFQDDVFPD TAVIWEPVLS
       850        860        870        880        890        900
AEAWLQGANG QPWLLSLQPP DMSPVSQAPR EAPARRAPSS AQYLEEKSDQ QKKEELLNAM
       910        920
VAKLGNREDP LPQDSFEGVD EDEWD         10         20         30         40         50         60
MNRFRVSKFR HTEARPPRRE SWISDIRAGT APSCRNHIKS SCSLIAFNSD RPGVLGIVPL
        70         80         90        100        110        120
QGQGEDKRRV AHLGCHSDLV TDLDFSPFDD FLLATGSADR TVKLWRLPGP GQALPSAPGV
       130        140        150        160        170        180
VLGPEDLPVE VLQFHPTSDG ILVSAAGTTV KVWDAAKQQP LTELAAHGDL VQSAVWSRDG
       190        200        210        220        230        240
ALVGTACKDK QLRIFDPRTK PRASQSTQAH ENSRDSRLAW MGTWEHLVST GFNQMREREV
       250        260        270        280        290        300
KLWDTRFFSS ALASLTLDTS LGCLVPLLDP DSGLLVLAGK GERQLYCYEV VPQQPALSPV
       310        320        330        340        350        360
TQCVLESVLR GAALVPRQAL AVMSCEVLRV LQLSDTAIVP IGYHVPRKAV EFHEDLFPDT
       370        380        390        400        410        420
AGCVPATDPH SWWAGDNQQV QKVSLNPACR PHPSFTSCLV PPAEPLPDTA QPAVMETPVG
       430        440        450        460        470        480
DADASEGFSS PPSSLTSPST PSSLGPSLSS TSGIGTSPSL RSLQSLLGPS SKFRHAQGTV
       490        500        510        520        530        540
LHRDSHITNL KGLNLTTPGE SDGFCANKLR VAVPLLSSGG QVAVLELRKP GRLPDTALPT
       550        560        570        580        590        600
LQNGAAVTDL AWDPFDPHRL AVAGEDARIR LWRVPAEGLE EVLTTPETVL TGHTEKICSL
       610        620        630        640        650        660
RFHPLAANVL ASSSYDLTVR IWDLQAGADR LKLQGHQDQI FSLAWSPDGQ QLATVCKDGR
       670        680        690        700        710        720
VRVYRPRSGP EPLQEGPGPK GGRGARIVWV CDGRCLLVSG FDSQSERQLL LYEAEALAGG
       730        740        750        760        770        780
PLAVLGLDVA PSTLLPSYDP DTGLVLLTGK GDTRVFLYEL LPESPFFLEC NSFTSPDPHK
       790        800        810        820        830        840
GLVLLPKTEC DVREVELMRC LRLRQSSLEP VAFRLPRVRK EFFQDDVFPD TAVIWEPVLS
       850        860        870        880        890        900
AEAWLQGANG QPWLLSLQPP DMSPVSQAPR EAPARRAPSS AQYLEEKSDQ QKKEELLNAM
       910        920
VAKLGNREDP LPQDSFEGVD EDEWD         10         20         30         40         50         60
MNRFRVSKFR HTEARPPRRE SWISDIRAGT APSCRNHIKS SCSLIAFNSD RPGVLGIVPL
        70         80         90        100        110        120
QGQGEDKRRV AHLGCHSDLV TDLDFSPFDD FLLATGSADR TVKLWRLPGP GQALPSAPGV
       130        140        150        160        170        180
VLGPEDLPVE VLQFHPTSDG ILVSAAGTTV KVWDAAKQQP LTELAAHGDL VQSAVWSRDG
       190        200        210        220        230        240
ALVGTACKDK QLRIFDPRTK PRASQSTQAH ENSRDSRLAW MGTWEHLVST GFNQMREREV
       250        260        270        280        290        300
KLWDTRFFSS ALASLTLDTS LGCLVPLLDP DSGLLVLAGK GERQLYCYEV VPQQPALSPV
       310        320        330        340        350        360
TQCVLESVLR GAALVPRQAL AVMSCEVLRV LQLSDTAIVP IGYHVPRKAV EFHEDLFPDT
       370        380        390        400        410        420
AGCVPATDPH SWWAGDNQQV QKVSLNPACR PHPSFTSCLV PPAEPLPDTA QPAVMETPVG
       430        440        450        460        470        480
DADASEGFSS PPSSLTSPST PSSLGPSLSS TSGIGTSPSL RSLQSLLGPS SKFRHAQGTV
       490        500        510        520        530        540
LHRDSHITNL KGLNLTTPGE SDGFCANKLR VAVPLLSSGG QVAVLELRKP GRLPDTALPT
       550        560        570        580        590        600
LQNGAAVTDL AWDPFDPHRL AVAGEDARIR LWRVPAEGLE EVLTTPETVL TGHTEKICSL
       610        620        630        640        650        660
RFHPLAANVL ASSSYDLTVR IWDLQAGADR LKLQGHQDQI FSLAWSPDGQ QLATVCKDGR
       670        680        690        700        710        720
VRVYRPRSGP EPLQEGPGPK GGRGARIVWV CDGRCLLVSG FDSQSERQLL LYEAEALAGG
       730        740        750        760        770        780
PLAVLGLDVA PSTLLPSYDP DTGLVLLTGK GDTRVFLYEL LPESPFFLEC NSFTSPDPHK
       790        800        810        820        830        840
GLVLLPKTEC DVREVELMRC LRLRQSSLEP VAFRLPRVRK EFFQDDVFPD TAVIWEPVLS
       850        860        870        880        890        900
AEAWLQGANG QPWLLSLQPP DMSPVSQAPR EAPARRAPSS AQYLEEKSDQ QKKEELLNAM
       910        920
VAKLGNREDP LPQDSFEGVD EDEWD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P57737-1-unknown	MNRFRV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P57737-1-unknown	MNRFRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71454
P57737-1-unknown	MNRFRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71455
P57737-1-unknown	MNRFRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71456
P57737-427-unknown	GFSSPP...	427	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175521
P57737-427-unknown	GFSSPP...	427	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175519
P57737-427-unknown	GFSSPP...	427	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175520
P57737-427-	GFSSPP...	427		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P57737-445-unknown	GPSLSS...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182839
P57737-445-unknown	GPSLSS...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182837
P57737-445-unknown	GPSLSS...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182838
P57737-445-	GPSLSS...	445		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P57737-450-unknown	STSGIG...	450	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182843
P57737-450-unknown	STSGIG...	450	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182841
P57737-450-unknown	STSGIG...	450	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182842
P57737-450-	STSGIG...	450		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P57737-831-unknown	TAVIWE...	831	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11733
P57737-831-unknown	TAVIWE...	831	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156252
P57737-831-unknown	TAVIWE...	831	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156544
P57737-831-unknown	TAVIWE...	831	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156609

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DVFPDT	830	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11733
...DVFPDT	830	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139720
...DVFPDT	830	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140028
...DVFPDT	830	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140094
...EDEWD	925	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EDEWD	925	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67072
...EDEWD	925	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67074

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	830	FPDT.\|.TAVI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)