P56182: Ribosomal RNA processing protein 1 homolog A

General Information

Protein names	- Ribosomal RNA processing protein 1 homolog A - Novel nuclear protein 1 - NNP-1 - Nucleolar protein Nop52 - RRP1-like protein
Gene names	RRP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P56182

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVSRVQLPPE IQLAQRLAGN EQVTRDRAVR KLRKYIVART QRAAGGFTHD ELLKVWKGLF
        70         80         90        100        110        120
YCMWMQDKPL LQEELGRTIS QLVHAFQTTE AQHLFLQAFW QTMNREWTGI DRLRLDKFYM
       130        140        150        160        170        180
LMRMVLNESL KVLKMQGWEE RQIEELLELL MTEILHPSSQ APNGVKSHFI EIFLEELTKV
       190        200        210        220        230        240
GAEELTADQN LKFIDPFCRI AARTKDSLVL NNITRGIFET IVEQAPLAIE DLLNELDTQD
       250        260        270        280        290        300
EEVASDSDES SEGGERGDAL SQKRSEKPPA GSICRAEPEA GEEQAGDDRD SGGPVLQFDY
       310        320        330        340        350        360
EAVANRLFEM ASRQSTPSQN RKRLYKVIRK LQDLAGGIFP EDEIPEKACR RLLEGRRQKK
       370        380        390        400        410        420
TKKQKRLLRL QQERGKGEKE PPSPGMERKR SRRRGVGADP EARAEAGEQP GTAERALLRD
       430        440        450        460
QPRGRGQRGA RQRRRTPRPL TSARAKAANV QEPEKKKKRR E

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P56182-1-unknown	MVSRVQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P56182-228-unknown	AIEDLL...	228	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14219
P56182-291-	SGGPVL...	291		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P56182-300-unknown	YEAVAN...	300	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11725
P56182-447-	AANVQE...	447		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EQAPLA	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14219
...VLQFDY	299	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11725
...KKRRE	461	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	227	APLA.\|.AIED	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	299	QFDY.\|.YEAV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)