Q96MW1: Coiled-coil domain-containing protein 43

General Information

Protein names	- Coiled-coil domain-containing protein 43
Gene names	CCDC43
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96MW1

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAPSEVAAI APGEGDGGGG GFGSWLDGRL EALGVDRAVY GAYILGILQE EEEEEKLDAL
        70         80         90        100        110        120
QGILSAFLEE DSLLNICKEI VERWSETQNV VTKVKKEDEV QAIATLIEKQ AQIVVKPRMV
       130        140        150        160        170        180
SEEEKQRKAA LLAQYADVTD EEDEADEKDD SGATTMNIGS DKLLFRNTNV EDVLNARKLE
       190        200        210        220
RDSLRDESQR KKEQDKLQRE RDKLAKQERK EKEKKRTQRG ERKR

Isoforms

- Isoform 2 of Coiled-coil domain-containing protein 43

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96MW1-1-unknown	MAAPSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96MW1-1-unknown	MAAPSE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69688
Q96MW1-2-acetylation	AAPSEV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96MW1-2-acetylation	AAPSEV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178676
Q96MW1-17-unknown	GGGGGF...	17		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165681
Q96MW1-17-	GGGGGF...	17			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96MW1-112-unknown	QIVVKP...	112		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168478
Q96MW1-112-	QIVVKP...	112			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q96MW1-162-unknown	KLLFRN...	162		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13091

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NIGSDK	161	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13091
	...GERKR	224	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	161	GSDK.\|.KLLF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)