Q8NFC6: Biorientation of chromosomes in cell division protein 1-like 1 {ECO:0000305}
Protein names | - Biorientation of chromosomes in cell division protein 1-like 1 {ECO:0000305} |
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Gene names | BOD1L1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8NFC6 |
15
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MATNPQPQPP PPAPPPPPPQ PQPQPPPPPP GPGAGPGAGG AGGAGAGAGD PQLVAMIVNH
70 80 90 100 110 120
LKSQGLFDQF RRDCLADVDT KPAYQNLRQR VDNFVANHLA THTWSPHLNK NQLRNNIRQQ
130 140 150 160 170 180
VLKSGMLESG IDRIISQVVD PKINHTFRPQ VEKAVHEFLA TLNHKEEGSG NTAPDDEKPD
190 200 210 220 230 240
TSLITQGVPT PGPSANVAND AMSILETITS LNQEASAARA STETSNAKTS ERASKKLPSQ
250 260 270 280 290 300
PTTDTSTDKE RTSEDMADKE KSTADSGGEG LETAPKSEEF SDLPCPVEEI KNYTKEHNNL
310 320 330 340 350 360
ILLNKDVQQE SSEQKNKSTD KGEKKPDSNE KGERKKEKKE KTEKKFDHSK KSEDTQKVKD
370 380 390 400 410 420
EKQAKEKEVE SLKLPSEKNS NKAKTVEGTK EDFSLIDSDV DGLTDITVSS VHTSDLSSFE
430 440 450 460 470 480
EDTEEEVVTS DSMEEGEITS DDEEKNKQNK TKTQTSDSSE GKTKSVRHAY VHKPYLYSKY
490 500 510 520 530 540
YSDSDDELTV EQRRQSIAKE KEERLLRRQI NREKLEEKRK QKAEKTKSSK TKGQGRSSVD
550 560 570 580 590 600
LEESSTKSLE PKAARIKEVL KERKVLEKKV ALSKKRKKDS RNVEENSKKK QQYEEDSKET
610 620 630 640 650 660
LKTSEHCEKE KISSSKELKH VHAKSEPSKP ARRLSESLHV VDENKNESKL EREHKRRTST
670 680 690 700 710 720
PVIMEGVQEE TDTRDVKRQV ERSEICTEEP QKQKSTLKNE KHLKKDDSET PHLKSLLKKE
730 740 750 760 770 780
VKSSKEKPER EKTPSEDKLS VKHKYKGDCM HKTGDETELH SSEKGLKVEE NIQKQSQQTK
790 800 810 820 830 840
LSSDDKTERK SKHRNERKLS VLGKDGKPVS EYIIKTDENV RKENNKKERR LSAEKTKAEH
850 860 870 880 890 900
KSRRSSDSKI QKDSLGSKQH GITLQRRSES YSEDKCDMDS TNMDSNLKPE EVVHKEKRRT
910 920 930 940 950 960
KSLLEEKLVL KSKSKTQGKQ VKVVETELQE GATKQATTPK PDKEKNTEEN DSEKQRKSKV
970 980 990 1000 1010 1020
EDKPFEETGV EPVLETASSS AHSTQKDSSH RAKLPLAKEK YKSDKDSTST RLERKLSDGH
1030 1040 1050 1060 1070 1080
KSRSLKHSSK DIKKKDENKS DDKDGKEVDS SHEKARGNSS LMEKKLSRRL CENRRGSLSQ
1090 1100 1110 1120 1130 1140
EMAKGEEKLA ANTLSTPSGS SLQRPKKSGD MTLIPEQEPM EIDSEPGVEN VFEVSKTQDN
1150 1160 1170 1180 1190 1200
RNNNSQQDID SENMKQKTSA TVQKDELRTC TADSKATAPA YKPGRGTGVN SNSEKHADHR
1210 1220 1230 1240 1250 1260
STLTKKMHIQ SAVSKMNPGE KEPIHRGTTE VNIDSETVHR MLLSAPSEND RVQKNLKNTA
1270 1280 1290 1300 1310 1320
AEEHVAQGDA TLEHSTNLDS SPSLSSVTVV PLRESYDPDV IPLFDKRTVL EGSTASTSPA
1330 1340 1350 1360 1370 1380
DHSALPNQSL TVRESEVLKT SDSKEGGEGF TVDTPAKASI TSKRHIPEAH QATLLDGKQG
1390 1400 1410 1420 1430 1440
KVIMPLGSKL TGVIVENENI TKEGGLVDMA KKENDLNAEP NLKQTIKATV ENGKKDGIAV
1450 1460 1470 1480 1490 1500
DHVVGLNTEK YAETVKLKHK RSPGKVKDIS IDVERRNENS EVDTSAGSGS APSVLHQRNG
1510 1520 1530 1540 1550 1560
QTEDVATGPR RAEKTSVATS TEGKDKDVTL SPVKAGPATT TSSETRQSEV ALPCTSIEAD
1570 1580 1590 1600 1610 1620
EGLIIGTHSR NNPLHVGAEA SECTVFAAAE EGGAVVTEGF AESETFLTST KEGESGECAV
1630 1640 1650 1660 1670 1680
AESEDRAADL LAVHAVKIEA NVNSVVTEEK DDAVTSAGSE EKCDGSLSRD SEIVEGTITF
1690 1700 1710 1720 1730 1740
ISEVESDGAV TSAGTEIRAG SISSEEVDGS QGNMMRMGPK KETEGTVTCT GAEGRSDNFV
1750 1760 1770 1780 1790 1800
ICSVTGAGPR EERMVTGAGV VLGDNDAPPG TSASQEGDGS VNDGTEGESA VTSTGITEDG
1810 1820 1830 1840 1850 1860
EGPASCTGSE DSSEGFAISS ESEENGESAM DSTVAKEGTN VPLVAAGPCD DEGIVTSTGA
1870 1880 1890 1900 1910 1920
KEEDEEGEDV VTSTGRGNEI GHASTCTGLG EESEGVLICE SAEGDSQIGT VVEHVEAEAG
1930 1940 1950 1960 1970 1980
AAIMNANENN VDSMSGTEKG SKDTDICSSA KGIVESSVTS AVSGKDEVTP VPGGCEGPMT
1990 2000 2010 2020 2030 2040
SAASDQSDSQ LEKVEDTTIS TGLVGGSYDV LVSGEVPECE VAHTSPSEKE DEDIITSVEN
2050 2060 2070 2080 2090 2100
EECDGLMATT ASGDITNQNS LAGGKNQGKV LIISTSTTND YTPQVSAITD VEGGLSDALR
2110 2120 2130 2140 2150 2160
TEENMEGTRV TTEEFEAPMP SAVSGDDSQL TASRSEEKDE CAMISTSIGE EFELPISSAT
2170 2180 2190 2200 2210 2220
TIKCAESLQP VAAAVEERAT GPVLISTADF EGPMPSAPPE AESPLASTSK EEKDECALIS
2230 2240 2250 2260 2270 2280
TSIAEECEAS VSGVVVESEN ERAGTVMEEK DGSGIISTSS VEDCEGPVSS AVPQEEGDPS
2290 2300 2310 2320 2330 2340
VTPAEEMGDT AMISTSTSEG CEAVMIGAVL QDEDRLTITR VEDLSDAAII STSTAECMPI
2350 2360 2370 2380 2390 2400
SASIDRHEEN QLTADNPEGN GDLSATEVSK HKVPMPSLIA ENNCRCPGPV RGGKEPGPVL
2410 2420 2430 2440 2450 2460
AVSTEEGHNG PSVHKPSAGQ GHPSAVCAEK EEKHGKECPE IGPFAGRGQK ESTLHLINAE
2470 2480 2490 2500 2510 2520
EKNVLLNSLQ KEDKSPETGT AGGSSTASYS AGRGLEGNAN SPAHLRGPEQ TSGQTAKDPS
2530 2540 2550 2560 2570 2580
VSIRYLAAVN TGAIKADDMP PVQGTVAEHS FLPAEQQGSE DNLKTSTTKC ITGQESKIAP
2590 2600 2610 2620 2630 2640
SHTMIPPATY SVALLAPKCE QDLTIKNDYS GKWTDQASAE KTGDDNSTRK SFPEEGDIMV
2650 2660 2670 2680 2690 2700
TVSSEENVCD IGNEESPLNV LGGLKLKANL KMEAYVPSEE EKNGEILAPP ESLCGGKPSG
2710 2720 2730 2740 2750 2760
IAELQREPLL VNESLNVENS GFRTNEEIHS ESYNKGEISS GRKDNAEAIS GHSVEADPKE
2770 2780 2790 2800 2810 2820
VEEEERHMPK RKRKQHYLSS EDEPDDNPDV LDSRIETAQR QCPETEPHDT KEENSRDLEE
2830 2840 2850 2860 2870 2880
LPKTSSETNS TTSRVMEEKD EYSSSETTGE KPEQNDDDTI KSQEEDQPII IKRKRGRPRK
2890 2900 2910 2920 2930 2940
YPVETTLKMK DDSKTDTGIV TVEQSPSSSK LKVMQTDESN KETANLQERS ISNDDGEEKI
2950 2960 2970 2980 2990 3000
VTSVRRRGRK PKRSLTVSDD AESSEPERKR QKSVSDPVED KKEQESDEEE EEEEEDEPSG
3010 3020 3030 3040 3050
ATTRSTTRSE AQRSKTQLSP SIKRKREVSP PGARTRGQQR VEEAPVKKAK R
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
15 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8NFC6-1-unknown | MATNPQ... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8NFC6-201-unknown | AMSILE... | 201 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12913 | |||
Q8NFC6-262- | STADSG... | 262 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q8NFC6-997-unknown | AKEKYK... | 997 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14774 | |||
Q8NFC6-1280- | SSPSLS... | 1280 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q8NFC6-1295- | SYDPDV... | 1295 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q8NFC6-1484- | TSAGSG... | 1484 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q8NFC6-1484- | TSAGSG... | 1484 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q8NFC6-1487- | GSGSAP... | 1487 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q8NFC6-1490- | SAPSVL... | 1490 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q8NFC6-1688- | GAVTSA... | 1688 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q8NFC6-1709-unknown | GSQGNM... | 1709 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q8NFC6-2045- | GLMATT... | 2045 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q8NFC6-2045-unknown | GLMATT... | 2045 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q8NFC6-2048- | ATTASG... | 2048 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q8NFC6-2048- | ATTASG... | 2048 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q8NFC6-2167- | SLQPVA... | 2167 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...NVANDA | 200 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12913 | |||
...AKLPLA | 996 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14774 | |||
...KKAKR | 3051 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 200 | ANDA.|.AMSI | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAM_HUMAN | 996 | LPLA.|.AKEK | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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