Q59H18: Serine/threonine-protein kinase TNNI3K

General Information

Protein names	- Serine/threonine-protein kinase TNNI3K - 2.7.11.1 - Cardiac ankyrin repeat kinase - Cardiac troponin I-interacting kinase - TNNI3-interacting kinase
Gene names	TNNI3K
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q59H18

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGNYKSRPTQ TCTDEWKKKV SESYVITIER LEDDLQIKEK ELTELRNIFG SDEAFSKVNL
        70         80         90        100        110        120
NYRTENGLSL LHLCCICGGK KSHIRTLMLK GLRPSRLTRN GFTALHLAVY KDNAELITSL
       130        140        150        160        170        180
LHSGADIQQV GYGGLTALHI ATIAGHLEAA DVLLQHGANV NIQDAVFFTP LHIAAYYGHE
       190        200        210        220        230        240
QVTRLLLKFG ADVNVSGEVG DRPLHLASAK GFLNIAKLLM EEGSKADVNA QDNEDHVPLH
       250        260        270        280        290        300
FCSRFGHHDI VKYLLQSDLE VQPHVVNIYG DTPLHLACYN GKFEVAKEII QISGTESLTK
       310        320        330        340        350        360
ENIFSETAFH SACTYGKSID LVKFLLDQNV ININHQGRDG HTGLHSACYH GHIRLVQFLL
       370        380        390        400        410        420
DNGADMNLVA CDPSRSSGEK DEQTCLMWAY EKGHDAIVTL LKHYKRPQDE LPCNEYSQPG
       430        440        450        460        470        480
GDGSYVSVPS PLGKIKSMTK EKADILLLRA GLPSHFHLQL SEIEFHEIIG SGSFGKVYKG
       490        500        510        520        530        540
RCRNKIVAIK RYRANTYCSK SDVDMFCREV SILCQLNHPC VIQFVGACLN DPSQFAIVTQ
       550        560        570        580        590        600
YISGGSLFSL LHEQKRILDL QSKLIIAVDV AKGMEYLHNL TQPIIHRDLN SHNILLYEDG
       610        620        630        640        650        660
HAVVADFGES RFLQSLDEDN MTKQPGNLRW MAPEVFTQCT RYTIKADVFS YALCLWEILT
       670        680        690        700        710        720
GEIPFAHLKP AAAAADMAYH HIRPPIGYSI PKPISSLLIR GWNACPEGRP EFSEVVMKLE
       730        740        750        760        770        780
ECLCNIELMS PASSNSSGSL SPSSSSDCLV NRGGPGRSHV AALRSRFELE YALNARSYAA
       790        800        810        820        830
LSQSAGQYSS QGLSLEEMKR SLQYTPIDKY GYVSDPMSSM HFHSCRNSSS FEDSS

Isoforms

- Isoform 1 of Serine/threonine-protein kinase TNNI3K - Isoform 3 of Serine/threonine-protein kinase TNNI3K - Isoform 4 of Serine/threonine-protein kinase TNNI3K

Sequence View

        10         20         30         40         50         60
MGNYKSRPTQ TCTDEWKKKV SESYVITIER LEDDLQIKEK ELTELRNIFG SDEAFSKVNL
        70         80         90        100        110        120
NYRTENGLSL LHLCCICGGK KSHIRTLMLK GLRPSRLTRN GFTALHLAVY KDNAELITSL
       130        140        150        160        170        180
LHSGADIQQV GYGGLTALHI ATIAGHLEAA DVLLQHGANV NIQDAVFFTP LHIAAYYGHE
       190        200        210        220        230        240
QVTRLLLKFG ADVNVSGEVG DRPLHLASAK GFLNIAKLLM EEGSKADVNA QDNEDHVPLH
       250        260        270        280        290        300
FCSRFGHHDI VKYLLQSDLE VQPHVVNIYG DTPLHLACYN GKFEVAKEII QISGTESLTK
       310        320        330        340        350        360
ENIFSETAFH SACTYGKSID LVKFLLDQNV ININHQGRDG HTGLHSACYH GHIRLVQFLL
       370        380        390        400        410        420
DNGADMNLVA CDPSRSSGEK DEQTCLMWAY EKGHDAIVTL LKHYKRPQDE LPCNEYSQPG
       430        440        450        460        470        480
GDGSYVSVPS PLGKIKSMTK EKADILLLRA GLPSHFHLQL SEIEFHEIIG SGSFGKVYKG
       490        500        510        520        530        540
RCRNKIVAIK RYRANTYCSK SDVDMFCREV SILCQLNHPC VIQFVGACLN DPSQFAIVTQ
       550        560        570        580        590        600
YISGGSLFSL LHEQKRILDL QSKLIIAVDV AKGMEYLHNL TQPIIHRDLN SHNILLYEDG
       610        620        630        640        650        660
HAVVADFGES RFLQSLDEDN MTKQPGNLRW MAPEVFTQCT RYTIKADVFS YALCLWEILT
       670        680        690        700        710        720
GEIPFAHLKP AAAAADMAYH HIRPPIGYSI PKPISSLLIR GWNACPEGRP EFSEVVMKLE
       730        740        750        760        770        780
ECLCNIELMS PASSNSSGSL SPSSSSDCLV NRGGPGRSHV AALRSRFELE YALNARSYAA
       790        800        810        820        830
LSQSAGQYSS QGLSLEEMKR SLQYTPIDKY GYVSDPMSSM HFHSCRNSSS FEDSS         10         20         30         40         50         60
MGNYKSRPTQ TCTDEWKKKV SESYVITIER LEDDLQIKEK ELTELRNIFG SDEAFSKVNL
        70         80         90        100        110        120
NYRTENGLSL LHLCCICGGK KSHIRTLMLK GLRPSRLTRN GFTALHLAVY KDNAELITSL
       130        140        150        160        170        180
LHSGADIQQV GYGGLTALHI ATIAGHLEAA DVLLQHGANV NIQDAVFFTP LHIAAYYGHE
       190        200        210        220        230        240
QVTRLLLKFG ADVNVSGEVG DRPLHLASAK GFLNIAKLLM EEGSKADVNA QDNEDHVPLH
       250        260        270        280        290        300
FCSRFGHHDI VKYLLQSDLE VQPHVVNIYG DTPLHLACYN GKFEVAKEII QISGTESLTK
       310        320        330        340        350        360
ENIFSETAFH SACTYGKSID LVKFLLDQNV ININHQGRDG HTGLHSACYH GHIRLVQFLL
       370        380        390        400        410        420
DNGADMNLVA CDPSRSSGEK DEQTCLMWAY EKGHDAIVTL LKHYKRPQDE LPCNEYSQPG
       430        440        450        460        470        480
GDGSYVSVPS PLGKIKSMTK EKADILLLRA GLPSHFHLQL SEIEFHEIIG SGSFGKVYKG
       490        500        510        520        530        540
RCRNKIVAIK RYRANTYCSK SDVDMFCREV SILCQLNHPC VIQFVGACLN DPSQFAIVTQ
       550        560        570        580        590        600
YISGGSLFSL LHEQKRILDL QSKLIIAVDV AKGMEYLHNL TQPIIHRDLN SHNILLYEDG
       610        620        630        640        650        660
HAVVADFGES RFLQSLDEDN MTKQPGNLRW MAPEVFTQCT RYTIKADVFS YALCLWEILT
       670        680        690        700        710        720
GEIPFAHLKP AAAAADMAYH HIRPPIGYSI PKPISSLLIR GWNACPEGRP EFSEVVMKLE
       730        740        750        760        770        780
ECLCNIELMS PASSNSSGSL SPSSSSDCLV NRGGPGRSHV AALRSRFELE YALNARSYAA
       790        800        810        820        830
LSQSAGQYSS QGLSLEEMKR SLQYTPIDKY GYVSDPMSSM HFHSCRNSSS FEDSS         10         20         30         40         50         60
MGNYKSRPTQ TCTDEWKKKV SESYVITIER LEDDLQIKEK ELTELRNIFG SDEAFSKVNL
        70         80         90        100        110        120
NYRTENGLSL LHLCCICGGK KSHIRTLMLK GLRPSRLTRN GFTALHLAVY KDNAELITSL
       130        140        150        160        170        180
LHSGADIQQV GYGGLTALHI ATIAGHLEAA DVLLQHGANV NIQDAVFFTP LHIAAYYGHE
       190        200        210        220        230        240
QVTRLLLKFG ADVNVSGEVG DRPLHLASAK GFLNIAKLLM EEGSKADVNA QDNEDHVPLH
       250        260        270        280        290        300
FCSRFGHHDI VKYLLQSDLE VQPHVVNIYG DTPLHLACYN GKFEVAKEII QISGTESLTK
       310        320        330        340        350        360
ENIFSETAFH SACTYGKSID LVKFLLDQNV ININHQGRDG HTGLHSACYH GHIRLVQFLL
       370        380        390        400        410        420
DNGADMNLVA CDPSRSSGEK DEQTCLMWAY EKGHDAIVTL LKHYKRPQDE LPCNEYSQPG
       430        440        450        460        470        480
GDGSYVSVPS PLGKIKSMTK EKADILLLRA GLPSHFHLQL SEIEFHEIIG SGSFGKVYKG
       490        500        510        520        530        540
RCRNKIVAIK RYRANTYCSK SDVDMFCREV SILCQLNHPC VIQFVGACLN DPSQFAIVTQ
       550        560        570        580        590        600
YISGGSLFSL LHEQKRILDL QSKLIIAVDV AKGMEYLHNL TQPIIHRDLN SHNILLYEDG
       610        620        630        640        650        660
HAVVADFGES RFLQSLDEDN MTKQPGNLRW MAPEVFTQCT RYTIKADVFS YALCLWEILT
       670        680        690        700        710        720
GEIPFAHLKP AAAAADMAYH HIRPPIGYSI PKPISSLLIR GWNACPEGRP EFSEVVMKLE
       730        740        750        760        770        780
ECLCNIELMS PASSNSSGSL SPSSSSDCLV NRGGPGRSHV AALRSRFELE YALNARSYAA
       790        800        810        820        830
LSQSAGQYSS QGLSLEEMKR SLQYTPIDKY GYVSDPMSSM HFHSCRNSSS FEDSS

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q59H18-1-unknown	MGNYKS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q59H18-487-unknown	VAIKRY...	487	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12464
Q59H18-487-unknown	VAIKRY...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt154437
Q59H18-487-unknown	VAIKRY...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt154438

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CRNKIV	486	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12464
...CRNKIV	486	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137858
...CRNKIV	486	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137859
...FEDSS	835	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q59H18: Serine/threonine-protein kinase TNNI3K

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates