P52298: Nuclear cap-binding protein subunit 2

General Information

Protein names	- Nuclear cap-binding protein subunit 2 - 20 kDa nuclear cap-binding protein - Cell proliferation-inducing gene 55 protein - NCBP 20 kDa subunit - CBP20 - NCBP-interacting protein 1 - NIP1
Gene names	NCBP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P52298

5 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Nuclear cap-binding protein subunit 2 - Isoform 3 of Nuclear cap-binding protein subunit 2

Sequence View

        10         20         30         40         50         60
MSGGLLKALR SDSYVELSQY RDQHFRGDNE EQEKLLKKSC TLYVGNLSFY TTEEQIYELF
        70         80         90        100        110        120
SKSGDIKKII MGLDKMKKTA CGFCFVEYYS RADAENAMRY INGTRLDDRI IRTDWDAGFK
       130        140        150
EGRQYGRGRS GGQVRDEYRQ DYDAGRGGYG KLAQNQ         10         20         30         40         50         60
MSGGLLKALR SDSYVELSQY RDQHFRGDNE EQEKLLKKSC TLYVGNLSFY TTEEQIYELF
        70         80         90        100        110        120
SKSGDIKKII MGLDKMKKTA CGFCFVEYYS RADAENAMRY INGTRLDDRI IRTDWDAGFK
       130        140        150
EGRQYGRGRS GGQVRDEYRQ DYDAGRGGYG KLAQNQ

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P52298-2-unknown	MSGGLL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P52298-1-unknown	MSGGLL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82368
P52298-2-Acetylation	SGGLLK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P52298-2-Acetylation	SGGLLK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P52298-2-Acetylation	SGGLLK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P52298-2-Acetylation	SGGLLK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110136
P52298-13-unknown	SYVELS...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11655
P52298-13-unknown	SYVELS...	13		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136428
P52298-71-unknown	MGLDKM...	71		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000413518
P52298-71-unknown	MGLDKM...	71		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000394105
P52298-71-unknown	MGLDKM...	71		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000389315
P52298-71-unknown	MGLDKM...	71		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196497

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ALRSDS	12	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11655
...YGKLAQ	153	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000389315
...YGKLAQ	153	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155000
...YGKLAQ	153	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155001
...LAQNQ	156		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAQNQ	156		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LAQNQ	156	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LAQNQ	156	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77986
...LAQNQ	156	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77985
...LAQNQ	156		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAQNQ	156		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	12	RSDS.\|.SYVE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)