Q7Z2T5: TRMT1-like protein

General Information

Protein names	- TRMT1-like protein - 2.1.1.-
Gene names	TRMT1L
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z2T5

7 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MENMAEEELL PLEKEEVEVA QVQVPTPARD SAGVPAPAPD SALDSAPTPA SAPAPAPALA
        70         80         90        100        110        120
QAPALSPSLA SAPEEAKSKR HISIQRQLAD LENLAFVTDG NFDSASSLNS DNLDAGNRQA
       130        140        150        160        170        180
CPLCPKEKFR ACNSHKLRRH LQNLHWKVSV EFEGYRMCIC HLPCRPVKPN IIGEQITSKM
       190        200        210        220        230        240
GAHYHCIICS ATITRRTDML GHVRRHMNKG ETKSSYIAAS TAKPPKEILK EADTDVQVCP
       250        260        270        280        290        300
NYSIPQKTDS YFNPKMKLNR QLIFCTLAAL AEERKPLECL DAFGATGIMG LQWAKHLGNA
       310        320        330        340        350        360
VKVTINDLNE NSVTLIQENC HLNKLKVVVD SKEKEKSDDI LEEGEKNLGN IKVTKMDANV
       370        380        390        400        410        420
LMHLRSFDFI HLDPFGTSVN YLDSAFRNIR NLGIVSVTST DISSLYAKAQ HVARRHYGCN
       430        440        450        460        470        480
IVRTEYYKEL AARIVVAAVA RAAARCNKGI EVLFAVALEH FVLVVVRVLR GPTSADETAK
       490        500        510        520        530        540
KIQYLIHCQW CEERIFQKDG NMVEENPYRQ LPCNCHGSMP GKTAIELGPL WSSSLFNTGF
       550        560        570        580        590        600
LKRMLFESLH HGLDDIQTLI KTLIFESECT PQSQFSIHAS SNVNKQEENG VFIKTTDDTT
       610        620        630        640        650        660
TDNYIAQGKR KSNEMITNLG KKQKTDVSTE HPPFYYNIHR HSIKGMNMPK LKKFLCYLSQ
       670        680        690        700        710        720
AGFRVSRTHF DPMGVRTDAP LMQFKSILLK YSTPTYTGGQ SESHVQSASE DTVTERVEMS
       730
VNDKAEASGC RRW

Isoforms

- Isoform 2 of TRMT1-like protein

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z2T5-1-unknown	MENMAE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z2T5-41-unknown	SALDSA...	41	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12673
Q7Z2T5-51-unknown	SAPAPA...	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14667
Q7Z2T5-109-unknown	NSDNLD...	109	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14668
Q7Z2T5-157-unknown	MCICHL...	157	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93105
Q7Z2T5-243-	SIPQKT...	243		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q7Z2T5-243-	SIPQKT...	243		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q7Z2T5-243-unknown	SIPQKT...	243	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167982

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APAPDS	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12673
...APTPAS	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14667
...SASSLN	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14668
...GCRRW	733	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	40	APDS.\|.SALD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	50	TPAS.\|.SAPA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	108	SSLN.\|.NSDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)