Q6IEG0: U11/U12 small nuclear ribonucleoprotein 48 kDa protein

General Information

Protein names	- U11/U12 small nuclear ribonucleoprotein 48 kDa protein - U11/U12 snRNP 48 kDa protein - U11/U12-48K
Gene names	SNRNP48
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6IEG0

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGEPPPVEE RRRLQEELNE FVESGCRTLE EVTASLGWDL DSLDPGEEEA AEDEVVICPY
        70         80         90        100        110        120
DSNHHMPKSS LAKHMASCRL RKMGYTKEEE DEMYNPEFFY ENVKIPSITL NKDSQFQIIK
       130        140        150        160        170        180
QARTAVGKDS DCYNQRIYSS LPVEVPLNHK RFVCDLTQAD RLALYDFVVE ETKKKRSDSQ
       190        200        210        220        230        240
IIENDSDLFV DLAAKINQDN SRKSPKSYLE ILAEVRDYKR RRQSYRAKNV HITKKSYTEV
       250        260        270        280        290        300
IRDVINVHME ELSNHWQEEQ EKAEDDAEKN EERRSASVDS RQSGGSYLDA ECSRHRRDRS
       310        320        330
RSPHKRKRNK DKDKNCESRR RKERDGERHH SHKRRKQKI

Isoforms

- Isoform 2 of U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6IEG0-1-unknown	MEGEPP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6IEG0-1-unknown	MEGEPP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90151
Q6IEG0-1-acetylation	MEGEPP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q6IEG0-1-acetylation	MEGEPP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6IEG0-1-acetylation	MEGEPP...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163064
Q6IEG0-186-unknown	SDLFVD...	186		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12572

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IIENDS	185	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12572
	...RKQKI	339	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	185	ENDS.\|.SDLF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)