Q14157: Ubiquitin-associated protein 2-like

General Information

Protein names	- Ubiquitin-associated protein 2-like - Protein NICE-4
Gene names	UBAP2L
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14157

59 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ubiquitin-associated protein 2-like - Isoform 3 of Ubiquitin-associated protein 2-like - Isoform 4 of Ubiquitin-associated protein 2-like - Isoform 5 of Ubiquitin-associated protein 2-like

Sequence View

        10         20         30         40         50         60
MMTSVGTNRA RGNWEQPQNQ NQTQHKQRPQ ATAEQIRLAQ MISDHNDADF EEKVKQLIDI
        70         80         90        100        110        120
TGKNQDECVI ALHDCNGDVN RAINVLLEGN PDTHSWEMVG KKKGVSGQKD GGQTESNEEG
       130        140        150        160        170        180
KENRDRDRDY SRRRGGPPRR GRGASRGREF RGQENGLDGT KSGGPSGRGT ERGRRGRGRG
       190        200        210        220        230        240
RGGSGRRGGR FSAQGMGTFN PADYAEPANT DDNYGNSSGN TWNNTGHFEP DDGTSAWRTA
       250        260        270        280        290        300
TEEWGTEDWN EDLSETKIFT ASNVSSVPLP AENVTITAGQ RIDLAVLLGK TPSTMENDSS
       310        320        330        340        350        360
NLDPSQAPSL AQPLVFSNSK QTAISQPASG NTFSHHSMVS MLGKGFGDVG EAKGGSTTGS
       370        380        390        400        410        420
QFLEQFKTAQ ALAQLAAQHS QSGSTTTSSW DMGSTTQSPS LVQYDLKNPS DSAVHSPFTK
       430        440        450        460        470        480
RQAFTPSSTM MEVFLQEKSP AVATSTAAPP PPSSPLPSKS TSAPQMSPGS SDNQSSSPQP
       490        500        510        520        530        540
AQQKLKQQKK KASLTSKIPA LAVEMPGSAD ISGLNLQFGA LQFGSEPVLS DYESTPTTSA
       550        560        570        580        590        600
SSSQAPSSLY TSTASESSST ISSNQSQESG YQSGPIQSTT YTSQNNAQGP LYEQRSTQTR
       610        620        630        640        650        660
RYPSSISSSP QKDLTQAKNG FSSVQATQLQ TTQSVEGATG SAVKSDSPST SSIPPLNETV
       670        680        690        700        710        720
SAASLLTTTN QHSSSLGGLS HSEEIPNTTT TQHSSTLSTQ QNTLSSSTSS GRTSTSTLLH
       730        740        750        760        770        780
TSVESEANLH SSSSTFSTTS STVSAPPPVV SVSSSLNSGS SLGLSLGSNS TVTASTRSSV
       790        800        810        820        830        840
ATTSGKAPPN LPPGVPPLLP NPYIMAPGLL HAYPPQVYGY DDLQMLQTRF PLDYYSIPFP
       850        860        870        880        890        900
TPTTPLTGRD GSLASNPYSG DLTKFGRGDA SSPAPATTLA QPQQNQTQTH HTTQQTFLNP
       910        920        930        940        950        960
ALPPGYSYTS LPYYTGVPGL PSTFQYGPAV FPVAPTSSKQ HGVNVSVNAS ATPFQQPSGY
       970        980        990       1000       1010       1020
GSHGYNTGVS VTSSNTGVPD ISGSVYSKTQ QSFEKQGFHS GTPAASFNLP SALGSGGPIN
      1030       1040       1050       1060       1070       1080
PATAAAYPPA PFMHILTPHQ QPHSQILHHH LQQDGQTGSG QRSQTSSIPQ KPQTNKSAYN

SYSWGAN         10         20         30         40         50         60
MMTSVGTNRA RGNWEQPQNQ NQTQHKQRPQ ATAEQIRLAQ MISDHNDADF EEKVKQLIDI
        70         80         90        100        110        120
TGKNQDECVI ALHDCNGDVN RAINVLLEGN PDTHSWEMVG KKKGVSGQKD GGQTESNEEG
       130        140        150        160        170        180
KENRDRDRDY SRRRGGPPRR GRGASRGREF RGQENGLDGT KSGGPSGRGT ERGRRGRGRG
       190        200        210        220        230        240
RGGSGRRGGR FSAQGMGTFN PADYAEPANT DDNYGNSSGN TWNNTGHFEP DDGTSAWRTA
       250        260        270        280        290        300
TEEWGTEDWN EDLSETKIFT ASNVSSVPLP AENVTITAGQ RIDLAVLLGK TPSTMENDSS
       310        320        330        340        350        360
NLDPSQAPSL AQPLVFSNSK QTAISQPASG NTFSHHSMVS MLGKGFGDVG EAKGGSTTGS
       370        380        390        400        410        420
QFLEQFKTAQ ALAQLAAQHS QSGSTTTSSW DMGSTTQSPS LVQYDLKNPS DSAVHSPFTK
       430        440        450        460        470        480
RQAFTPSSTM MEVFLQEKSP AVATSTAAPP PPSSPLPSKS TSAPQMSPGS SDNQSSSPQP
       490        500        510        520        530        540
AQQKLKQQKK KASLTSKIPA LAVEMPGSAD ISGLNLQFGA LQFGSEPVLS DYESTPTTSA
       550        560        570        580        590        600
SSSQAPSSLY TSTASESSST ISSNQSQESG YQSGPIQSTT YTSQNNAQGP LYEQRSTQTR
       610        620        630        640        650        660
RYPSSISSSP QKDLTQAKNG FSSVQATQLQ TTQSVEGATG SAVKSDSPST SSIPPLNETV
       670        680        690        700        710        720
SAASLLTTTN QHSSSLGGLS HSEEIPNTTT TQHSSTLSTQ QNTLSSSTSS GRTSTSTLLH
       730        740        750        760        770        780
TSVESEANLH SSSSTFSTTS STVSAPPPVV SVSSSLNSGS SLGLSLGSNS TVTASTRSSV
       790        800        810        820        830        840
ATTSGKAPPN LPPGVPPLLP NPYIMAPGLL HAYPPQVYGY DDLQMLQTRF PLDYYSIPFP
       850        860        870        880        890        900
TPTTPLTGRD GSLASNPYSG DLTKFGRGDA SSPAPATTLA QPQQNQTQTH HTTQQTFLNP
       910        920        930        940        950        960
ALPPGYSYTS LPYYTGVPGL PSTFQYGPAV FPVAPTSSKQ HGVNVSVNAS ATPFQQPSGY
       970        980        990       1000       1010       1020
GSHGYNTGVS VTSSNTGVPD ISGSVYSKTQ QSFEKQGFHS GTPAASFNLP SALGSGGPIN
      1030       1040       1050       1060       1070       1080
PATAAAYPPA PFMHILTPHQ QPHSQILHHH LQQDGQTGSG QRSQTSSIPQ KPQTNKSAYN

SYSWGAN         10         20         30         40         50         60
MMTSVGTNRA RGNWEQPQNQ NQTQHKQRPQ ATAEQIRLAQ MISDHNDADF EEKVKQLIDI
        70         80         90        100        110        120
TGKNQDECVI ALHDCNGDVN RAINVLLEGN PDTHSWEMVG KKKGVSGQKD GGQTESNEEG
       130        140        150        160        170        180
KENRDRDRDY SRRRGGPPRR GRGASRGREF RGQENGLDGT KSGGPSGRGT ERGRRGRGRG
       190        200        210        220        230        240
RGGSGRRGGR FSAQGMGTFN PADYAEPANT DDNYGNSSGN TWNNTGHFEP DDGTSAWRTA
       250        260        270        280        290        300
TEEWGTEDWN EDLSETKIFT ASNVSSVPLP AENVTITAGQ RIDLAVLLGK TPSTMENDSS
       310        320        330        340        350        360
NLDPSQAPSL AQPLVFSNSK QTAISQPASG NTFSHHSMVS MLGKGFGDVG EAKGGSTTGS
       370        380        390        400        410        420
QFLEQFKTAQ ALAQLAAQHS QSGSTTTSSW DMGSTTQSPS LVQYDLKNPS DSAVHSPFTK
       430        440        450        460        470        480
RQAFTPSSTM MEVFLQEKSP AVATSTAAPP PPSSPLPSKS TSAPQMSPGS SDNQSSSPQP
       490        500        510        520        530        540
AQQKLKQQKK KASLTSKIPA LAVEMPGSAD ISGLNLQFGA LQFGSEPVLS DYESTPTTSA
       550        560        570        580        590        600
SSSQAPSSLY TSTASESSST ISSNQSQESG YQSGPIQSTT YTSQNNAQGP LYEQRSTQTR
       610        620        630        640        650        660
RYPSSISSSP QKDLTQAKNG FSSVQATQLQ TTQSVEGATG SAVKSDSPST SSIPPLNETV
       670        680        690        700        710        720
SAASLLTTTN QHSSSLGGLS HSEEIPNTTT TQHSSTLSTQ QNTLSSSTSS GRTSTSTLLH
       730        740        750        760        770        780
TSVESEANLH SSSSTFSTTS STVSAPPPVV SVSSSLNSGS SLGLSLGSNS TVTASTRSSV
       790        800        810        820        830        840
ATTSGKAPPN LPPGVPPLLP NPYIMAPGLL HAYPPQVYGY DDLQMLQTRF PLDYYSIPFP
       850        860        870        880        890        900
TPTTPLTGRD GSLASNPYSG DLTKFGRGDA SSPAPATTLA QPQQNQTQTH HTTQQTFLNP
       910        920        930        940        950        960
ALPPGYSYTS LPYYTGVPGL PSTFQYGPAV FPVAPTSSKQ HGVNVSVNAS ATPFQQPSGY
       970        980        990       1000       1010       1020
GSHGYNTGVS VTSSNTGVPD ISGSVYSKTQ QSFEKQGFHS GTPAASFNLP SALGSGGPIN
      1030       1040       1050       1060       1070       1080
PATAAAYPPA PFMHILTPHQ QPHSQILHHH LQQDGQTGSG QRSQTSSIPQ KPQTNKSAYN

SYSWGAN         10         20         30         40         50         60
MMTSVGTNRA RGNWEQPQNQ NQTQHKQRPQ ATAEQIRLAQ MISDHNDADF EEKVKQLIDI
        70         80         90        100        110        120
TGKNQDECVI ALHDCNGDVN RAINVLLEGN PDTHSWEMVG KKKGVSGQKD GGQTESNEEG
       130        140        150        160        170        180
KENRDRDRDY SRRRGGPPRR GRGASRGREF RGQENGLDGT KSGGPSGRGT ERGRRGRGRG
       190        200        210        220        230        240
RGGSGRRGGR FSAQGMGTFN PADYAEPANT DDNYGNSSGN TWNNTGHFEP DDGTSAWRTA
       250        260        270        280        290        300
TEEWGTEDWN EDLSETKIFT ASNVSSVPLP AENVTITAGQ RIDLAVLLGK TPSTMENDSS
       310        320        330        340        350        360
NLDPSQAPSL AQPLVFSNSK QTAISQPASG NTFSHHSMVS MLGKGFGDVG EAKGGSTTGS
       370        380        390        400        410        420
QFLEQFKTAQ ALAQLAAQHS QSGSTTTSSW DMGSTTQSPS LVQYDLKNPS DSAVHSPFTK
       430        440        450        460        470        480
RQAFTPSSTM MEVFLQEKSP AVATSTAAPP PPSSPLPSKS TSAPQMSPGS SDNQSSSPQP
       490        500        510        520        530        540
AQQKLKQQKK KASLTSKIPA LAVEMPGSAD ISGLNLQFGA LQFGSEPVLS DYESTPTTSA
       550        560        570        580        590        600
SSSQAPSSLY TSTASESSST ISSNQSQESG YQSGPIQSTT YTSQNNAQGP LYEQRSTQTR
       610        620        630        640        650        660
RYPSSISSSP QKDLTQAKNG FSSVQATQLQ TTQSVEGATG SAVKSDSPST SSIPPLNETV
       670        680        690        700        710        720
SAASLLTTTN QHSSSLGGLS HSEEIPNTTT TQHSSTLSTQ QNTLSSSTSS GRTSTSTLLH
       730        740        750        760        770        780
TSVESEANLH SSSSTFSTTS STVSAPPPVV SVSSSLNSGS SLGLSLGSNS TVTASTRSSV
       790        800        810        820        830        840
ATTSGKAPPN LPPGVPPLLP NPYIMAPGLL HAYPPQVYGY DDLQMLQTRF PLDYYSIPFP
       850        860        870        880        890        900
TPTTPLTGRD GSLASNPYSG DLTKFGRGDA SSPAPATTLA QPQQNQTQTH HTTQQTFLNP
       910        920        930        940        950        960
ALPPGYSYTS LPYYTGVPGL PSTFQYGPAV FPVAPTSSKQ HGVNVSVNAS ATPFQQPSGY
       970        980        990       1000       1010       1020
GSHGYNTGVS VTSSNTGVPD ISGSVYSKTQ QSFEKQGFHS GTPAASFNLP SALGSGGPIN
      1030       1040       1050       1060       1070       1080
PATAAAYPPA PFMHILTPHQ QPHSQILHHH LQQDGQTGSG QRSQTSSIPQ KPQTNKSAYN

SYSWGAN

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

59 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14157-1-unknown	MMTSVG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93666
Q14157-1-unknown	MMTSVG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93667
Q14157-1-unknown	MMTSVG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93668
Q14157-1-Acetylation	MMTSVG...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14157-1-Acetylation	MMTSVG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q14157-1-Acetylation	MMTSVG...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q14157-1-Acetylation	MMTSVG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q14157-1-Acetylation	MMTSVG...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109215
Q14157-1-Acetylation	MMTSVG...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109216
Q14157-1-Acetylation	MMTSVG...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109217
Q14157-41-unknown	MISDHN...	41		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169798
Q14157-41-unknown	MISDHN...	41		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169799
Q14157-41-unknown	MISDHN...	41		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169800
Q14157-41-	MISDHN...	41			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14157-41-	MISDHN...	41			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-89-unknown	GNPDTH...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6388
Q14157-89-unknown	GNPDTH...	89		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141787
Q14157-89-unknown	GNPDTH...	89		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141788
Q14157-89-unknown	GNPDTH...	89		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141790
Q14157-217-	SSGNTW...	217			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-217-unknown	SSGNTW...	217		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170192
Q14157-217-unknown	SSGNTW...	217		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170191
Q14157-217-unknown	SSGNTW...	217		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170193
Q14157-263-	NVSSVP...	263			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-263-unknown	NVSSVP...	263		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172060
Q14157-263-unknown	NVSSVP...	263		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172059
Q14157-263-unknown	NVSSVP...	263		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172061
Q14157-266-unknown	SVPLPA...	266		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166573
Q14157-266-unknown	SVPLPA...	266		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166572
Q14157-266-unknown	SVPLPA...	266		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166574
Q14157-266-	SVPLPA...	266			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-266-	SVPLPA...	266			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-266-	SVPLPA...	266			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14157-266-	SVPLPA...	266			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14157-266-	SVPLPA...	266			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14157-299-unknown	SSNLDP...	299		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12205
Q14157-299-unknown	SSNLDP...	299		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149658
Q14157-299-unknown	SSNLDP...	299		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149837
Q14157-299-unknown	SSNLDP...	299		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149838
Q14157-299-	SSNLDP...	299			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q14157-299-	SSNLDP...	299			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-299-	SSNLDP...	299			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-393-unknown	GSTTQS...	393		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174760
Q14157-393-unknown	GSTTQS...	393		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174759
Q14157-393-unknown	GSTTQS...	393		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174761
Q14157-393-	GSTTQS...	393			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-408-	NPSDSA...	408			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14157-408-unknown	NPSDSA...	408		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169794
Q14157-408-unknown	NPSDSA...	408		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169793
Q14157-408-unknown	NPSDSA...	408		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169795
Q14157-412-	SAVHSP...	412			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-412-unknown	SAVHSP...	412		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172055
Q14157-412-unknown	SAVHSP...	412		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172054
Q14157-412-unknown	SAVHSP...	412		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172056
Q14157-428-unknown	STMMEV...	428		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166583
Q14157-428-unknown	STMMEV...	428		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166582
Q14157-428-unknown	STMMEV...	428		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166584
Q14157-428-	STMMEV...	428			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-428-	STMMEV...	428			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-428-	STMMEV...	428			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14157-447-unknown	AAPPPP...	447		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166578
Q14157-447-unknown	AAPPPP...	447		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166577
Q14157-447-unknown	AAPPPP...	447		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166579
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14157-447-	AAPPPP...	447			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14157-586-	NAQGPL...	586			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-586-unknown	NAQGPL...	586		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170187
Q14157-586-unknown	NAQGPL...	586		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170186
Q14157-586-unknown	NAQGPL...	586		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170188
Q14157-587-unknown	AQGPLY...	587		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166598
Q14157-587-unknown	AQGPLY...	587		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166597
Q14157-587-unknown	AQGPLY...	587		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166599
Q14157-587-	AQGPLY...	587			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-587-	AQGPLY...	587			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-587-	AQGPLY...	587			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14157-605-unknown	SISSSP...	605		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172065
Q14157-605-unknown	SISSSP...	605		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172064
Q14157-605-unknown	SISSSP...	605		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172066
Q14157-605-	SISSSP...	605			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-620-unknown	GFSSVQ...	620		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170177
Q14157-620-unknown	GFSSVQ...	620		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170176
Q14157-620-unknown	GFSSVQ...	620		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170178
Q14157-620-	GFSSVQ...	620			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-630-	QTTQSV...	630			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-630-unknown	QTTQSV...	630		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173064
Q14157-630-unknown	QTTQSV...	630		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173063
Q14157-630-unknown	QTTQSV...	630		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173065
Q14157-634-unknown	SVEGAT...	634		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166588
Q14157-634-unknown	SVEGAT...	634		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166587
Q14157-634-unknown	SVEGAT...	634		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166589
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14157-634-	SVEGAT...	634			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14157-694-	SSTLST...	694			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-694-unknown	SSTLST...	694		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172050
Q14157-694-unknown	SSTLST...	694		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172049
Q14157-694-unknown	SSTLST...	694		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172051
Q14157-695-	STLSTQ...	695			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-695-unknown	STLSTQ...	695		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172040
Q14157-695-unknown	STLSTQ...	695		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172039
Q14157-695-unknown	STLSTQ...	695		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172041
Q14157-696-	TLSTQQ...	696			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-696-unknown	TLSTQQ...	696		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172045
Q14157-696-unknown	TLSTQQ...	696		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172044
Q14157-696-unknown	TLSTQQ...	696		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172046
Q14157-698-	STQQNT...	698			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-698-unknown	STQQNT...	698		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170172
Q14157-698-unknown	STQQNT...	698		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170171
Q14157-698-unknown	STQQNT...	698		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170173
Q14157-703-	TLSSST...	703			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-703-unknown	TLSSST...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170182
Q14157-703-unknown	TLSSST...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170181
Q14157-703-unknown	TLSSST...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170183
Q14157-767-	GSNSTV...	767			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-767-unknown	GSNSTV...	767		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173059
Q14157-767-unknown	GSNSTV...	767		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173058
Q14157-767-unknown	GSNSTV...	767		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173060
Q14157-770-unknown	STVTAS...	770		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170197
Q14157-770-unknown	STVTAS...	770		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170196
Q14157-770-unknown	STVTAS...	770		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170198
Q14157-770-	STVTAS...	770			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-812-unknown	AYPPQV...	812		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174755
Q14157-812-unknown	AYPPQV...	812		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174754
Q14157-812-unknown	AYPPQV...	812		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174756
Q14157-812-	AYPPQV...	812			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-836-unknown	SIPFPT...	836		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166593
Q14157-836-unknown	SIPFPT...	836		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166592
Q14157-836-unknown	SIPFPT...	836		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt166594
Q14157-836-	SIPFPT...	836			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q14157-836-	SIPFPT...	836			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14157-836-	SIPFPT...	836			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-836-	SIPFPT...	836			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q14157-836-	SIPFPT...	836			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14157-851-	GSLASN...	851			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q14157-851-	GSLASN...	851			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-851-	GSLASN...	851			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14157-851-	GSLASN...	851			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q14157-851-unknown	GSLASN...	851			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q14157-851-unknown	GSLASN...	851		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162269
Q14157-851-unknown	GSLASN...	851		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162268
Q14157-851-unknown	GSLASN...	851		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162270
Q14157-852-	SLASNP...	852			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-852-unknown	SLASNP...	852		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174765
Q14157-852-unknown	SLASNP...	852		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174764
Q14157-852-unknown	SLASNP...	852		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174766
Q14157-854-	ASNPYS...	854			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14157-854-unknown	ASNPYS...	854		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174770
Q14157-854-unknown	ASNPYS...	854		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174769
Q14157-854-unknown	ASNPYS...	854		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174771

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NVLLEG	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6388
...NVLLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124968
...NVLLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124969
...NVLLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124971
...TMENDS	298	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12205
...TMENDS	298	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133045
...TMENDS	298	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133228
...TMENDS	298	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133229
...SWGAN	1087	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SWGAN	1087	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89286

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	88	LLEG.\|.GNPD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	298	ENDS.\|.SSNL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)