Q6UX04: Spliceosome-associated protein CWC27 homolog {ECO:0000305}

General Information

Protein names	- Spliceosome-associated protein CWC27 homolog {ECO:0000305} - Antigen NY-CO-10 {ECO:0000303\|PubMed:9610721} - Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog {ECO:0000305\|PubMed:20676357} - PPIase CWC27 {ECO:0000305\|PubMed:20676357} - Serologically defined colon cancer antigen 10
Gene names	CWC27
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6UX04

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Peptidyl-prolyl cis-trans isomerase CWC27 homolog - Isoform 2 of Spliceosome-associated protein CWC27 homolog

Sequence View

        10         20         30         40         50         60
MSNIYIQEPP TNGKVLLKTT AGDIDIELWS KEAPKACRNF IQLCLEAYYD NTIFHRVVPG
        70         80         90        100        110        120
FIVQGGDPTG TGSGGESIYG APFKDEFHSR LRFNRRGLVA MANAGSHDNG SQFFFTLGRA
       130        140        150        160        170        180
DELNNKHTIF GKVTGDTVYN MLRLSEVDID DDERPHNPHK IKSCEVLFNP FDDIIPREIK
       190        200        210        220        230        240
RLKKEKPEEE VKKLKPKGTK NFSLLSFGEE AEEEEEEVNR VSQSMKGKSK SSHDLLKDDP
       250        260        270        280        290        300
HLSSVPVVES EKGDAPDLVD DGEDESAEHD EYIDGDEKNL MRERIAKKLK KDTSANVKSA
       310        320        330        340        350        360
GEGEVEKKSV SRSEELRKEA RQLKRELLAA KQKKVENAAK QAEKRSEEEE APPDGAVAEY
       370        380        390        400        410        420
RREKQKYEAL RKQQSKKGTS REDQTLALLN QFKSKLTQAI AETPENDIPE TEVEDDEGWM
       430        440        450        460        470
SHVLQFEDKS RKVKDASMQD SDTFEIYDPR NPVNKRRREE SKKLMREKKE RR         10         20         30         40         50         60
MSNIYIQEPP TNGKVLLKTT AGDIDIELWS KEAPKACRNF IQLCLEAYYD NTIFHRVVPG
        70         80         90        100        110        120
FIVQGGDPTG TGSGGESIYG APFKDEFHSR LRFNRRGLVA MANAGSHDNG SQFFFTLGRA
       130        140        150        160        170        180
DELNNKHTIF GKVTGDTVYN MLRLSEVDID DDERPHNPHK IKSCEVLFNP FDDIIPREIK
       190        200        210        220        230        240
RLKKEKPEEE VKKLKPKGTK NFSLLSFGEE AEEEEEEVNR VSQSMKGKSK SSHDLLKDDP
       250        260        270        280        290        300
HLSSVPVVES EKGDAPDLVD DGEDESAEHD EYIDGDEKNL MRERIAKKLK KDTSANVKSA
       310        320        330        340        350        360
GEGEVEKKSV SRSEELRKEA RQLKRELLAA KQKKVENAAK QAEKRSEEEE APPDGAVAEY
       370        380        390        400        410        420
RREKQKYEAL RKQQSKKGTS REDQTLALLN QFKSKLTQAI AETPENDIPE TEVEDDEGWM
       430        440        450        460        470
SHVLQFEDKS RKVKDASMQD SDTFEIYDPR NPVNKRRREE SKKLMREKKE RR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q6UX04-2-unknown	MSNIYI...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6UX04-1-unknown	MSNIYI...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72182
Q6UX04-2-Acetylation	SNIYIQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6UX04-2-Acetylation	SNIYIQ...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110399
Q6UX04-271-unknown	EYIDGD...	271		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12630
Q6UX04-271-unknown	EYIDGD...	271		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149144
Q6UX04-441-unknown	SDTFEI...	441		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12632
Q6UX04-443-unknown	TFEIYD...	443		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12633

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SAEHDE	270	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12630
...SAEHDE	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132529
...ASMQDS	440	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12632
...MQDSDT	442	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12633
...KKERR	472	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	270	EHDE.\|.EYID	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	440	MQDS.\|.SDTF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	442	DSDT.\|.TFEI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)