Q8WU90: Zinc finger CCCH domain-containing protein 15

General Information

Protein names	- Zinc finger CCCH domain-containing protein 15 - DRG family-regulatory protein 1 - Likely ortholog of mouse immediate early response erythropoietin 4
Gene names	ZC3H15
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8WU90

12 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPPKKQAQAG GSKKAEQKKK EKIIEDKTFG LKNKKGAKQQ KFIKAVTHQV KFGQQNPRQV
        70         80         90        100        110        120
AQSEAEKKLK KDDKKKELQE LNELFKPVVA AQKISKGADP KSVVCAFFKQ GQCTKGDKCK
       130        140        150        160        170        180
FSHDLTLERK CEKRSVYIDA RDEELEKDTM DNWDEKKLEE VVNKKHGEAE KKKPKTQIVC
       190        200        210        220        230        240
KHFLEAIENN KYGWFWVCPG GGDICMYRHA LPPGFVLKKD KKKEEKEDEI SLEDLIERER
       250        260        270        280        290        300
SALGPNVTKI TLESFLAWKK RKRQEKIDKL EQDMERRKAD FKAGKALVIS GREVFEFRPE
       310        320        330        340        350        360
LVNDDDEEAD DTRYTQGTGG DEVDDSVSVN DIDLSLYIPR DVDETGITVA SLERFSTYTS
       370        380        390        400        410        420
DKDENKLSEA SGGRAENGER SDLEEDNERE GTENGAIDAV PVDENLFTGE DLDELEEELN

TLDLEE

Isoforms

- Isoform 2 of Zinc finger CCCH domain-containing protein 15

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

12 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8WU90-1-unknown	MPPKKQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8WU90-42-	FIKAVT...	42		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q8WU90-81-unknown	LNELFK...	81	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19721
Q8WU90-82-unknown	NELFKP...	82		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q8WU90-206-unknown	MYRHAL...	206	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000440525
Q8WU90-323-unknown	VDDSVS...	323	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000415788
Q8WU90-328-	SVNDID...	328		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8WU90-331-unknown	DIDLSL...	331	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12939
Q8WU90-335-	SLYIPR...	335		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q8WU90-335-	SLYIPR...	335		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8WU90-336-	LYIPRD...	336		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q8WU90-336-	LYIPRD...	336		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8WU90-336-	LYIPRD...	336		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q8WU90-336-	LYIPRD...	336		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q8WU90-337-	YIPRDV...	337		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q8WU90-337-	YIPRDV...	337		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8WU90-337-	YIPRDV...	337		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q8WU90-337-	YIPRDV...	337		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q8WU90-366-unknown	KLSEAS...	366	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14788

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KELQEL	80	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19721
...SVSVND	330	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12939
...DKDENK	365	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14788
...LDLEE	426	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	80	LQEL.\|.LNEL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	330	SVND.\|.DIDL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	365	DENK.\|.KLSE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)