Q56NI9: N-acetyltransferase ESCO2

General Information

Protein names	- N-acetyltransferase ESCO2 - 2.3.1.- {ECO:0000269\|PubMed:15958495} - Establishment factor-like protein 2 - EFO2 {ECO:0000303\|PubMed:15958495} - EFO2p - hEFO2 - Establishment of cohesion 1 homolog 2 - ECO1 homolog 2
Gene names	ESCO2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q56NI9

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAALTPRKRK QDSLKCDSLL HFTENLFPSP NKKHCFYQNS DKNEENLHCS QQEHFVLSAL
        70         80         90        100        110        120
KTTEINRLPS ANQGSPFKSA LSTVSFYNQN KWYLNPLERK LIKESRSTCL KTNDEDKSFP
       130        140        150        160        170        180
IVTEKMQGKP VCSKKNNKKP QKSLTAKYQP KYRHIKPVSR NSRNSKQNRV IYKPIVEKEN
       190        200        210        220        230        240
NCHSAENNSN APRVLSQKIK PQVTLQGGAA FFVRKKSSLR KSSLENEPSL GRTQKSKSEV
       250        260        270        280        290        300
IEDSDVETVS EKKTFATRQV PKCLVLEEKL KIGLLSASSK NKEKLIKDSS DDRVSSKEHK
       310        320        330        340        350        360
VDKNEAFSSE DSLGENKTIS PKSTVYPIFS ASSVNSKRSL GEEQFSVGSV NFMKQTNIQK
       370        380        390        400        410        420
NTNTRDTSKK TKDQLIIDAG QKHFGATVCK SCGMIYTASN PEDEMQHVQH HHRFLEGIKY
       430        440        450        460        470        480
VGWKKERVVA EFWDGKIVLV LPHDPSFAIK KVEDVQELVD NELGFQQVVP KCPNKIKTFL
       490        500        510        520        530        540
FISDEKRVVG CLIAEPIKQA FRVLSEPIGP ESPSSTECPR AWQCSDVPEP AVCGISRIWV
       550        560        570        580        590        600
FRLKRRKRIA RRLVDTLRNC FMFGCFLSTD EIAFSDPTPD GKLFATKYCN TPNFLVYNFN

S

Isoforms

- Isoform 2 of N-acetyltransferase ESCO2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q56NI9-1-unknown	MAALTP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q56NI9-244-unknown	SDVETV...	244	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12463
Q56NI9-353-unknown	MKQTNI...	353	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000380563

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KPVCSK	133	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428027
...HSAENN	187	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428435
...EVIEDS	243	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12463
...STECPR	519	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428959
...YNFNS	601	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	243	IEDS.\|.SDVE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)