Q7Z478: ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068}

General Information

Protein names	- ATP-dependent RNA helicase DHX29 {ECO:0000255\|HAMAP-Rule:MF_03068} - 3.6.4.13 {ECO:0000255\|HAMAP-Rule:MF_03068} - DEAH box protein 29 {ECO:0000255\|HAMAP-Rule:MF_03068} - Nucleic acid helicase DDXx
Gene names	DHX29
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z478

6 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGGKNKKHKA PAAAVVRAAV SASRAKSAEA GIAGEAQSKK PVSRPATAAA AAAGSREPRV
        70         80         90        100        110        120
KQGPKIYSFN STNDSSGPAN LDKSILKVVI NNKLEQRIIG VINEHKKQNN DKGMISGRLT
       130        140        150        160        170        180
AKKLQDLYMA LQAFSFKTKD IEDAMTNTLL YGGDLHSALD WLCLNLSDDA LPEGFSQEFE
       190        200        210        220        230        240
EQQPKSRPKF QSPQIQATIS PPLQPKTKTY EEDPKSKPKK EEKNMEVNMK EWILRYAEQQ
       250        260        270        280        290        300
NEEEKNENSK SLEEEEKFDP NERYLHLAAK LLDAKEQAAT FKLEKNKQGQ KEAQEKIRKF
       310        320        330        340        350        360
QREMETLEDH PVFNPAMKIS HQQNERKKPP VATEGESALN FNLFEKSAAA TEEEKDKKKE
       370        380        390        400        410        420
PHDVRNFDYT ARSWTGKSPK QFLIDWVRKN LPKSPNPSFE KVPVGRYWKC RVRVIKSEDD
       430        440        450        460        470        480
VLVVCPTILT EDGMQAQHLG ATLALYRLVK GQSVHQLLPP TYRDVWLEWS DAEKKREELN
       490        500        510        520        530        540
KMETNKPRDL FIAKLLNKLK QQQQQQQQHS ENKRENSEDP EESWENLVSD EDFSALSLES
       550        560        570        580        590        600
ANVEDLEPVR NLFRKLQSTP KYQKLLKERQ QLPVFKHRDS IVETLKRHRV VVVAGETGSG
       610        620        630        640        650        660
KSTQVPHFLL EDLLLNEWEA SKCNIVCTQP RRISAVSLAN RVCDELGCEN GPGGRNSLCG
       670        680        690        700        710        720
YQIRMESRAC ESTRLLYCTT GVLLRKLQED GLLSNVSHVI VDEVHERSVQ SDFLLIILKE
       730        740        750        760        770        780
ILQKRSDLHL ILMSATVDSE KFSTYFTHCP ILRISGRSYP VEVFHLEDII EETGFVLEKD
       790        800        810        820        830        840
SEYCQKFLEE EEEVTINVTS KAGGIKKYQE YIPVQTGAHA DLNPFYQKYS SRTQHAILYM
       850        860        870        880        890        900
NPHKINLDLI LELLAYLDKS PQFRNIEGAV LIFLPGLAHI QQLYDLLSND RRFYSERYKV
       910        920        930        940        950        960
IALHSILSTQ DQAAAFTLPP PGVRKIVLAT NIAETGITIP DVVFVIDTGR TKENKYHESS
       970        980        990       1000       1010       1020
QMSSLVETFV SKASALQRQG RAGRVRDGFC FRMYTRERFE GFMDYSVPEI LRVPLEELCL
      1030       1040       1050       1060       1070       1080
HIMKCNLGSP EDFLSKALDP PQLQVISNAM NLLRKIGACE LNEPKLTPLG QHLAALPVNV
      1090       1100       1110       1120       1130       1140
KIGKMLIFGA IFGCLDPVAT LAAVMTEKSP FTTPIGRKDE ADLAKSALAM ADSDHLTIYN
      1150       1160       1170       1180       1190       1200
AYLGWKKARQ EGGYRSEITY CRRNFLNRTS LLTLEDVKQE LIKLVKAAGF SSSTTSTSWE
      1210       1220       1230       1240       1250       1260
GNRASQTLSF QEIALLKAVL VAGLYDNVGK IIYTKSVDVT EKLACIVETA QGKAQVHPSS
      1270       1280       1290       1300       1310       1320
VNRDLQTHGW LLYQEKIRYA RVYLRETTLI TPFPVLLFGG DIEVQHRERL LSIDGWIYFQ
      1330       1340       1350       1360
APVKIAVIFK QLRVLIDSVL RKKLENPKMS LENDKILQII TELIKTENN

Isoforms

Sequence View

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Physiological Relevance:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z478-1-unknown	MGGKNK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z478-27-unknown	SAEAGI...	27		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q7Z478-27-	SAEAGI...	27		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q7Z478-36-unknown	AQSKKP...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12683
Q7Z478-68-unknown	SFNSTN...	68		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q7Z478-68-	SFNSTN...	68		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIAGEA	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12683
...QSPQIQ	195	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000421435
...KTENN	1369	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	35	AGEA.\|.AQSK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)