P05060: Secretogranin-1
Protein names | - Secretogranin-1 - Chromogranin-B - CgB - Secretogranin I - SgI - PE-11 - GAWK peptide - CCB peptide |
---|---|
Gene names | CHGB |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P05060 |
2
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MQPTLLLSLL GAVGLAAVNS MPVDNRNHNE GMVTRCIIEV LSNALSKSSA PPITPECRQV
70 80 90 100 110 120
LKTSRKDVKD KETTENENTK FEVRLLRDPA DASEAHESSS RGEAGAPGEE DIQGPTKADT
130 140 150 160 170 180
EKWAEGGGHS RERADEPQWS LYPSDSQVSE EVKTRHSEKS QREDEEEEEG ENYQKGERGE
190 200 210 220 230 240
DSSEEKHLEE PGETQNAFLN ERKQASAIKK EELVARSETH AAGHSQEKTH SREKSSQESG
250 260 270 280 290 300
EETGSQENHP QESKGQPRSQ EESEEGEEDA TSEVDKRRTR PRHHHGRSRP DRSSQGGSLP
310 320 330 340 350 360
SEEKGHPQEE SEESNVSMAS LGEKRDHHST HYRASEEEPE YGEEIKGYPG VQAPEDLEWE
370 380 390 400 410 420
RYRGRGSEEY RAPRPQSEES WDEEDKRNYP SLELDKMAHG YGEESEEERG LEPGKGRHHR
430 440 450 460 470 480
GRGGEPRAYF MSDTREEKRF LGEGHHRVQE NQMDKARRHP QGAWKELDRN YLNYGEEGAP
490 500 510 520 530 540
GKWQQQGDLQ DTKENREEAR FQDKQYSSHH TAEKRKRLGE LFNPYYDPLQ WKSSHFERRD
550 560 570 580 590 600
NMNDNFLEGE EENELTLNEK NFFPEYNYDW WEKKPFSEDV NWGYEKRNLA RVPKLDLKRQ
610 620 630 640 650 660
YDRVAQLDQL LHYRKKSAEF PDFYDSEEPV STHQEAENEK DRADQTVLTE DEKKELENLA
670
AMDLELQKIA EKFSQRG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P05060-21-unknown | MPVDNR... | 21 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P05060-21-unknown | MPVDNR... | 21 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000416643 | |||
P05060-592-unknown | VPKLDL... | 592 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11044 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GHPQEE | 309 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000416643 | |||
...RNLARV | 591 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11044 | |||
...FSQRG | 677 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 591 | LARV.|.VPKL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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