Q9Y5S9: RNA-binding protein 8A

General Information

Protein names	- RNA-binding protein 8A - Binder of OVCA1-1 - BOV-1 - RNA-binding motif protein 8A - RNA-binding protein Y14 {ECO:0000303\|PubMed:11030346} - Ribonucleoprotein RBM8A
Gene names	RBM8A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y5S9

12 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADVLDLHEA GGEDFAMDED GDESIHKLKE KAKKRKGRGF GSEEGSRARM REDYDSVEQD
        70         80         90        100        110        120
GDEPGPQRSV EGWILFVTGV HEEATEEDIH DKFAEYGEIK NIHLNLDRRT GYLKGYTLVE
       130        140        150        160        170
YETYKEAQAA MEGLNGQDLM GQPISVDWCF VRGPPKGKRR GGRRRSRSPD RRRR

Isoforms

- Isoform 2 of RNA-binding protein 8A

Sequence View

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Protein Neighborhood

Domains & Features

12 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y5S9-2-unknown	MADVLD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y5S9-1-unknown	MADVLD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87152
Q9Y5S9-2-Acetylation	ADVLDL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y5S9-2-Acetylation	ADVLDL...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110831
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q9Y5S9-7-	LHEAGG...	7			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9Y5S9-7-unknown	LHEAGG...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1359
Q9Y5S9-7-unknown	LHEAGG...	7		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165650
Q9Y5S9-39-	GFGSEE...	39			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y5S9-50-	MREDYD...	50			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9Y5S9-50-unknown	MREDYD...	50		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176683
Q9Y5S9-54-unknown	YDSVEQ...	54		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13653
Q9Y5S9-54-unknown	YDSVEQ...	54		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196201
Q9Y5S9-56-unknown	SVEQDG...	56		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172245
Q9Y5S9-56-	SVEQDG...	56			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y5S9-56-	SVEQDG...	56			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9Y5S9-56-	SVEQDG...	56			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9Y5S9-56-	SVEQDG...	56			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9Y5S9-95-unknown	EYGEIK...	95		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19883
Q9Y5S9-95-unknown	EYGEIK...	95		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142087

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ADVLDL	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1359
...RMREDY	53	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13653
...HDKFAE	94	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19883
...HDKFAE	94	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125272
...DRRRR	174	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DRRRR	174	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82770

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP1_HUMAN	6	VLDL.\|.LHEA	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,
GRAB_HUMAN	53	REDY.\|.YDSV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MEP1B_HUMAN	94	KFAE.\|.EYGE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)