Q92620: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

General Information

Protein names	- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 - 3.6.4.13 - ATP-dependent RNA helicase DHX38 - DEAH box protein 38
Gene names	DHX38
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92620

5 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGDTSEDASI HRLEGTDLDC QVGGLICKSK SAASEQHVFK APAPRPSLLG LDLLASLKRR
        70         80         90        100        110        120
EREEKDDGED KKKSKVSSYK DWEESKDDQK DAEEEGGDQA GQNIRKDRHY RSARVETPSH
       130        140        150        160        170        180
PGGVSEEFWE RSRQRERERR EHGVYASSKE EKDWKKEKSR DRDYDRKRDR DERDRSRHSS
       190        200        210        220        230        240
RSERDGGSER SSRRNEPESP RHRPKDAATP SRSTWEEEDS GYGSSRRSQW ESPSPTPSYR
       250        260        270        280        290        300
DSERSHRLST RDRDRSVRGK YSDDTPLPTP SYKYNEWADD RRHLGSTPRL SRGRGRREEG
       310        320        330        340        350        360
EEGISFDTEE ERQQWEDDQR QADRDWYMMD EGYDEFHNPL AYSSEDYVRR REQHLHKQKQ
       370        380        390        400        410        420
KRISAQRRQI NEDNERWETN RMLTSGVVHR LEVDEDFEED NAAKVHLMVH NLVPPFLDGR
       430        440        450        460        470        480
IVFTKQPEPV IPVKDATSDL AIIARKGSQT VRKHREQKER KKAQHKHWEL AGTKLGDIMG
       490        500        510        520        530        540
VKKEEEPDKA VTEDGKVDYR TEQKFADHMK RKSEASSEFA KKKSILEQRQ YLPIFAVQQE
       550        560        570        580        590        600
LLTIIRDNSI VIVVGETGSG KTTQLTQYLH EDGYTDYGMI GCTQPRRVAA MSVAKRVSEE
       610        620        630        640        650        660
MGGNLGEEVG YAIRFEDCTS ENTLIKYMTD GILLRESLRE ADLDHYSAII MDEAHERSLN
       670        680        690        700        710        720
TDVLFGLLRE VVARRSDLKL IVTSATMDAE KFAAFFGNVP IFHIPGRTFP VDILFSKTPQ
       730        740        750        760        770        780
EDYVEAAVKQ SLQVHLSGAP GDILIFMPGQ EDIEVTSDQI VEHLEELENA PALAVLPIYS
       790        800        810        820        830        840
QLPSDLQAKI FQKAPDGVRK CIVATNIAET SLTVDGIMFV IDSGYCKLKV FNPRIGMDAL
       850        860        870        880        890        900
QIYPISQANA NQRSGRAGRT GPGQCFRLYT QSAYKNELLT TTVPEIQRTN LANVVLLLKS
       910        920        930        940        950        960
LGVQDLLQFH FMDPPPEDNM LNSMYQLWIL GALDNTGGLT STGRLMVEFP LDPALSKMLI
       970        980        990       1000       1010       1020
VSCDMGCSSE ILLIVSMLSV PAIFYRPKGR EEESDQIREK FAVPESDHLT YLNVYLQWKN
      1030       1040       1050       1060       1070       1080
NNYSTIWCND HFIHAKAMRK VREVRAQLKD IMVQQRMSLA SCGTDWDIVR KCICAAYFHQ
      1090       1100       1110       1120       1130       1140
AAKLKGIGEY VNIRTGMPCH LHPTSSLFGM GYTPDYIVYH ELVMTTKEYM QCVTAVDGEW
      1150       1160       1170       1180       1190       1200
LAELGPMFYS VKQAGKSRQE NRRRAKEEAS AMEEEMALAE EQLRARRQEQ EKRSPLGSVR
      1210       1220
STKIYTPGRK EQGEPMTPRR TPARFGL

Isoforms

- Isoform 2 of Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

Sequence View

        10         20         30         40         50         60
MGDTSEDASI HRLEGTDLDC QVGGLICKSK SAASEQHVFK APAPRPSLLG LDLLASLKRR
        70         80         90        100        110        120
EREEKDDGED KKKSKVSSYK DWEESKDDQK DAEEEGGDQA GQNIRKDRHY RSARVETPSH
       130        140        150        160        170        180
PGGVSEEFWE RSRQRERERR EHGVYASSKE EKDWKKEKSR DRDYDRKRDR DERDRSRHSS
       190        200        210        220        230        240
RSERDGGSER SSRRNEPESP RHRPKDAATP SRSTWEEEDS GYGSSRRSQW ESPSPTPSYR
       250        260        270        280        290        300
DSERSHRLST RDRDRSVRGK YSDDTPLPTP SYKYNEWADD RRHLGSTPRL SRGRGRREEG
       310        320        330        340        350        360
EEGISFDTEE ERQQWEDDQR QADRDWYMMD EGYDEFHNPL AYSSEDYVRR REQHLHKQKQ
       370        380        390        400        410        420
KRISAQRRQI NEDNERWETN RMLTSGVVHR LEVDEDFEED NAAKVHLMVH NLVPPFLDGR
       430        440        450        460        470        480
IVFTKQPEPV IPVKDATSDL AIIARKGSQT VRKHREQKER KKAQHKHWEL AGTKLGDIMG
       490        500        510        520        530        540
VKKEEEPDKA VTEDGKVDYR TEQKFADHMK RKSEASSEFA KKKSILEQRQ YLPIFAVQQE
       550        560        570        580        590        600
LLTIIRDNSI VIVVGETGSG KTTQLTQYLH EDGYTDYGMI GCTQPRRVAA MSVAKRVSEE
       610        620        630        640        650        660
MGGNLGEEVG YAIRFEDCTS ENTLIKYMTD GILLRESLRE ADLDHYSAII MDEAHERSLN
       670        680        690        700        710        720
TDVLFGLLRE VVARRSDLKL IVTSATMDAE KFAAFFGNVP IFHIPGRTFP VDILFSKTPQ
       730        740        750        760        770        780
EDYVEAAVKQ SLQVHLSGAP GDILIFMPGQ EDIEVTSDQI VEHLEELENA PALAVLPIYS
       790        800        810        820        830        840
QLPSDLQAKI FQKAPDGVRK CIVATNIAET SLTVDGIMFV IDSGYCKLKV FNPRIGMDAL
       850        860        870        880        890        900
QIYPISQANA NQRSGRAGRT GPGQCFRLYT QSAYKNELLT TTVPEIQRTN LANVVLLLKS
       910        920        930        940        950        960
LGVQDLLQFH FMDPPPEDNM LNSMYQLWIL GALDNTGGLT STGRLMVEFP LDPALSKMLI
       970        980        990       1000       1010       1020
VSCDMGCSSE ILLIVSMLSV PAIFYRPKGR EEESDQIREK FAVPESDHLT YLNVYLQWKN
      1030       1040       1050       1060       1070       1080
NNYSTIWCND HFIHAKAMRK VREVRAQLKD IMVQQRMSLA SCGTDWDIVR KCICAAYFHQ
      1090       1100       1110       1120       1130       1140
AAKLKGIGEY VNIRTGMPCH LHPTSSLFGM GYTPDYIVYH ELVMTTKEYM QCVTAVDGEW
      1150       1160       1170       1180       1190       1200
LAELGPMFYS VKQAGKSRQE NRRRAKEEAS AMEEEMALAE EQLRARRQEQ EKRSPLGSVR
      1210       1220
STKIYTPGRK EQGEPMTPRR TPARFGL

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q92620-2-unknown	MGDTSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q92620-2-Acetylation	GDTSED...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q92620-53-unknown	LLASLK...	53		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12995
Q92620-671-unknown	VVARRS...	671		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462965
Q92620-1012-unknown	LNVYLQ...	1012		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462397

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLGLDL	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12995
...SHPGGV	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457887
...QRERER	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455939
...ARFGL	1227	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q92620: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

General Information

5

N-termini

4

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates