P55201: Peregrin {ECO:0000305}
Protein names | - Peregrin {ECO:0000305} - Bromodomain and PHD finger-containing protein 1 {ECO:0000312|HGNC:HGNC:14255} - Protein Br140 {ECO:0000303|PubMed:7906940} |
---|---|
Gene names | BRPF1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P55201 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK
70 80 90 100 110 120
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS
130 140 150 160 170 180
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV
190 200 210 220 230 240
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI
250 260 270 280 290 300
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV
310 320 330 340 350 360
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV
370 380 390 400 410 420
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY
430 440 450 460 470 480
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS
490 500 510 520 530 540
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL
550 560 570 580 590 600
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER
610 620 630 640 650 660
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS
670 680 690 700 710 720
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR
730 740 750 760 770 780
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL
790 800 810 820 830 840
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS
850 860 870 880 890 900
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK
910 920 930 940 950 960
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK
970 980 990 1000 1010 1020
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP
1030 1040 1050 1060 1070 1080
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED
1090 1100 1110 1120 1130 1140
SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE
1150 1160 1170 1180 1190 1200
HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS
1210
KVQGEQSSET SDSD
Isoforms
- Isoform 2 of Peregrin - Isoform 3 of Peregrin - Isoform 4 of PeregrinSequence View
10 20 30 40 50 60
MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK
70 80 90 100 110 120
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS
130 140 150 160 170 180
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV
190 200 210 220 230 240
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI
250 260 270 280 290 300
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV
310 320 330 340 350 360
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV
370 380 390 400 410 420
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY
430 440 450 460 470 480
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS
490 500 510 520 530 540
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL
550 560 570 580 590 600
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER
610 620 630 640 650 660
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS
670 680 690 700 710 720
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR
730 740 750 760 770 780
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL
790 800 810 820 830 840
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS
850 860 870 880 890 900
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK
910 920 930 940 950 960
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK
970 980 990 1000 1010 1020
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP
1030 1040 1050 1060 1070 1080
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED
1090 1100 1110 1120 1130 1140
SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE
1150 1160 1170 1180 1190 1200
HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS
1210
KVQGEQSSET SDSD
10 20 30 40 50 60
MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK
70 80 90 100 110 120
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS
130 140 150 160 170 180
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV
190 200 210 220 230 240
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI
250 260 270 280 290 300
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV
310 320 330 340 350 360
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV
370 380 390 400 410 420
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY
430 440 450 460 470 480
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS
490 500 510 520 530 540
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL
550 560 570 580 590 600
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER
610 620 630 640 650 660
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS
670 680 690 700 710 720
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR
730 740 750 760 770 780
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL
790 800 810 820 830 840
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS
850 860 870 880 890 900
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK
910 920 930 940 950 960
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK
970 980 990 1000 1010 1020
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP
1030 1040 1050 1060 1070 1080
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED
1090 1100 1110 1120 1130 1140
SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE
1150 1160 1170 1180 1190 1200
HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS
1210
KVQGEQSSET SDSD
10 20 30 40 50 60
MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK
70 80 90 100 110 120
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS
130 140 150 160 170 180
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV
190 200 210 220 230 240
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI
250 260 270 280 290 300
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV
310 320 330 340 350 360
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV
370 380 390 400 410 420
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY
430 440 450 460 470 480
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS
490 500 510 520 530 540
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL
550 560 570 580 590 600
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER
610 620 630 640 650 660
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS
670 680 690 700 710 720
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR
730 740 750 760 770 780
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL
790 800 810 820 830 840
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS
850 860 870 880 890 900
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK
910 920 930 940 950 960
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK
970 980 990 1000 1010 1020
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP
1030 1040 1050 1060 1070 1080
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED
1090 1100 1110 1120 1130 1140
SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE
1150 1160 1170 1180 1190 1200
HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS
1210
KVQGEQSSET SDSD
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P55201-1-unknown | MGVDFD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P55201-1-unknown | MGVDFD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68650 | |||
P55201-1-unknown | MGVDFD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68651 | |||
P55201-1-unknown | MGVDFD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68652 | |||
P55201-103-unknown | LHGRVH... | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11700 | |||
P55201-103-unknown | LHGRVH... | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142566 | |||
P55201-103-unknown | LHGRVH... | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142567 | |||
P55201-103-unknown | LHGRVH... | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142568 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...MVEVDL | 102 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11700 | |||
...MVEVDL | 102 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125760 | |||
...MVEVDL | 102 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125761 | |||
...MVEVDL | 102 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125762 | |||
...TSDSD | 1214 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...TSDSD | 1214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64270 | |||
...TSDSD | 1214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64269 | |||
...TSDSD | 1214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64268 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 102 | EVDL.|.LHGR | inferred from experiment | unknown | MEROPS | Craik CS | Loeb CR et al.:Granzyme B proteolyzes receptor... (S01.010) | 16798735, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|