Q6JBY9: CapZ-interacting protein
Protein names | - CapZ-interacting protein - Protein kinase substrate CapZIP - RCSD domain-containing protein 1 |
---|---|
Gene names | RCSD1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q6JBY9 |
15
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEERPAETNA NVDNSASPSV AQLAGRFREQ AAAAKETPAS KPTRRKPPCS LPLFPPKVDL
70 80 90 100 110 120
GQNGEEKSPP NASHPPKFKV KSSPLIEKLQ ANLTFDPAAL LPGASPKSPG LKAMVSPFHS
130 140 150 160 170 180
PPSTPSSPGV RSRPSEAEEV PVSFDQPPEG SHLPCYNKVR TRGSIKRRPP SRRFRRSQSD
190 200 210 220 230 240
CGELGDFRAV ESSQQNGAKE EDGDEVLPSK SKAPGSPLSS EGAAGEGVRT LGPAEKPPLR
250 260 270 280 290 300
RSPSRTEKQE EDRATEEAKN GEKARRSSEE VDGQHPAQEE VPESPQTSGP EAENRCGSPR
310 320 330 340 350 360
EEKPAGEEAE MEKATEVKGE RVQNEEVGPE HDSQETKKLE EGAAVKETPH SPPGGVKGGD
370 380 390 400 410
VPKQEKGKEK QQEGAVLEPG CSPQTGPAQL ETSSEVQSEP AVPKPEDDTP VQDTKM
Isoforms
- Isoform 2 of CapZ-interacting proteinSequence View
10 20 30 40 50 60
MEERPAETNA NVDNSASPSV AQLAGRFREQ AAAAKETPAS KPTRRKPPCS LPLFPPKVDL
70 80 90 100 110 120
GQNGEEKSPP NASHPPKFKV KSSPLIEKLQ ANLTFDPAAL LPGASPKSPG LKAMVSPFHS
130 140 150 160 170 180
PPSTPSSPGV RSRPSEAEEV PVSFDQPPEG SHLPCYNKVR TRGSIKRRPP SRRFRRSQSD
190 200 210 220 230 240
CGELGDFRAV ESSQQNGAKE EDGDEVLPSK SKAPGSPLSS EGAAGEGVRT LGPAEKPPLR
250 260 270 280 290 300
RSPSRTEKQE EDRATEEAKN GEKARRSSEE VDGQHPAQEE VPESPQTSGP EAENRCGSPR
310 320 330 340 350 360
EEKPAGEEAE MEKATEVKGE RVQNEEVGPE HDSQETKKLE EGAAVKETPH SPPGGVKGGD
370 380 390 400 410
VPKQEKGKEK QQEGAVLEPG CSPQTGPAQL ETSSEVQSEP AVPKPEDDTP VQDTKM
Protein Neighborhood
Domains & Features
15 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q6JBY9-1-unknown | MEERPA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q6JBY9-1-acetylation | MEERPA... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
Q6JBY9-15- | SASPSV... | 15 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6JBY9-15- | SASPSV... | 15 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-15- | SASPSV... | 15 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-16- | ASPSVA... | 16 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-16- | ASPSVA... | 16 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-95- | FDPAAL... | 95 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-98- | AALLPG... | 98 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q6JBY9-98- | AALLPG... | 98 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-98- | AALLPG... | 98 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-108- | SPGLKA... | 108 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q6JBY9-113- | AMVSPF... | 113 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q6JBY9-113- | AMVSPF... | 113 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-113- | AMVSPF... | 113 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-114-unknown | MVSPFH... | 114 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q6JBY9-114- | MVSPFH... | 114 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6JBY9-114- | MVSPFH... | 114 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-197- | GAKEED... | 197 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6JBY9-273-unknown | GQHPAQ... | 273 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
Q6JBY9-273- | GQHPAQ... | 273 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q6JBY9-311-unknown | MEKATE... | 311 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71591 | |||
Q6JBY9-331-unknown | HDSQET... | 331 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12577 | |||
Q6JBY9-331-unknown | HDSQET... | 331 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136899 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EVGPEH | 330 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12577 | |||
...QDTKM | 416 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QDTKM | 416 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt67209 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 330 | GPEH.|.HDSQ | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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