O95926: Pre-mRNA-splicing factor SYF2

General Information

Protein names	- Pre-mRNA-splicing factor SYF2 - CCNDBP1-interactor - p29 {ECO:0000303\|PubMed:11118353}
Gene names	SYF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95926

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAIAASEVL VDSAEEGSLA AAAELAAQKR EQRLRKFREL HLMRNEARKL NHQEVVEEDK
        70         80         90        100        110        120
RLKLPANWEA KKARLEWELK EEEKKKECAA RGEDYEKVKL LEISAEDAER WERKKKRKNP
       130        140        150        160        170        180
DLGFSDYAAA QLRQYHRLTK QIKPDMETYE RLREKHGEEF FPTSNSLLHG THVPSTEEID
       190        200        210        220        230        240
RMVIDLEKQI EKRDKYSRRR PYNDDADIDY INERNAKFNK KAERFYGKYT AEIKQNLERG

TAV

Isoforms

- Isoform 2 of Pre-mRNA-splicing factor SYF2

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95926-1-unknown	MAAIAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91172
O95926-2-unknown	MAAIAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95926-2-Acetylation	AAIAAS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95926-2-Acetylation	AAIAAS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95926-2-Acetylation	AAIAAS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111166
O95926-13-	SAEEGS...	13			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95926-13-	SAEEGS...	13			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O95926-13-	SAEEGS...	13			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95926-13-	SAEEGS...	13			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O95926-13-	SAEEGS...	13			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95926-13-unknown	SAEEGS...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11034
O95926-13-unknown	SAEEGS...	13		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136397
O95926-170-unknown	GTHVPS...	170		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167338
O95926-170-	GTHVPS...	170			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95926-170-	GTHVPS...	170			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O95926-170-	GTHVPS...	170			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EVLVDS	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11034
...RGTAV	243	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RGTAV	243	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86790

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	12	LVDS.\|.SAEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)