Q9Y3C0: WASH complex subunit 3 {ECO:0000312|HGNC:HGNC:24256}

General Information

Protein names	- WASH complex subunit 3 {ECO:0000312\|HGNC:HGNC:24256} - Coiled-coil domain-containing protein 53
Gene names	CCDC53
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y3C0

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDEDGLPLMG SGIDLTKVPA IQQKRTVAFL NQFVVHTVQF LNRFSTVCEE KLADLSLRIQ
        70         80         90        100        110        120
QIETTLNILD AKLSSIPGLD DVTVEVSPLN VTSVTNGAHP EATSEQPQQN STQDSGLQES
       130        140        150        160        170        180
EVSAENILTV AKDPRYARYL KMVQVGVPVM AIRNKMISEG LDPDLLERPD APVPDGESEK
       190
TVEESSDSES SFSD

Isoforms

Sequence View

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Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y3C0-1-Acetylation	MDEDGL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y3C0-1-Acetylation	MDEDGL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y3C0-5-	GLPLMG...	5			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y3C0-51-unknown	KLADLS...	51		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000443922
Q9Y3C0-126-unknown	NILTVA...	126		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13629

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EVSAEN	125	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13629
	...SSFSD	194	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	125	SAEN.\|.NILT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)