Q7L4I2: Arginine/serine-rich coiled-coil protein 2

General Information

Protein names	- Arginine/serine-rich coiled-coil protein 2
Gene names	RSRC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7L4I2

6 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASDTERDG LAPEKTSPDR DKKKEQSEVS VSPRASKHHY SRSRSRSRER KRKSDNEGRK
        70         80         90        100        110        120
HRSRSRSKEG RRHESKDKSS KKHKSEEHND KEHSSDKGRE RLNSSENGED RHKRKERKSS
       130        140        150        160        170        180
RGRSHSRSRS RERRHRSRSR ERKKSRSRSR ERKKSRSRSR ERKKSRSRSR ERKRRIRSRS
       190        200        210        220        230        240
RSRSRHRHRT RSRSRTRSRS RDRKKRIEKP RRFSRSLSRT PSPPPFRGRN TAMDAQEALA
       250        260        270        280        290        300
RRLERAKKLQ EQREKEMVEK QKQQEIAAAA ATGGSVLNVA ALLASGTQVT PQIAMAAQMA
       310        320        330        340        350        360
ALQAKALAET GIAVPSYYNP AAVNPMKFAE QEKKRKMLWQ GKKEGDKSQS AEIWEKLNFG
       370        380        390        400        410        420
NKDQNVKFRK LMGIKSEDEA GCSSVDEESY KTLKQQEEVF RNLDAQYEMA RSQTHTQRGM
       430
GLGFTSSMRG MDAV

Isoforms

- Isoform 2 of Arginine/serine-rich coiled-coil protein 2

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7L4I2-2-unknown	MAASDT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7L4I2-2-Acetylation	AASDTE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7L4I2-231-	TAMDAQ...	231			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q7L4I2-231-unknown	TAMDAQ...	231			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q7L4I2-231-unknown	TAMDAQ...	231		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160225
Q7L4I2-327-unknown	KFAEQE...	327		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14664
Q7L4I2-327-unknown	KFAEQE...	327		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149314
Q7L4I2-389-unknown	SYKTLK...	389		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12669
Q7L4I2-389-unknown	SYKTLK...	389		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150759

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AVNPMK	326	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14664
...AVNPMK	326	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132699
...SVDEES	388	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12669
...SVDEES	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134159
...GMDAV	434	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GMDAV	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83909

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	326	NPMK.\|.KFAE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	388	DEES.\|.SYKT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)