P09211: Glutathione S-transferase P

General Information

Protein names	- Glutathione S-transferase P - 2.5.1.18 - GST class-pi - GSTP1-1
Gene names	GSTP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09211

10 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPPYTVVYFP VRGRCAALRM LLADQGQSWK EEVVTVETWQ EGSLKASCLY GQLPKFQDGD
        70         80         90        100        110        120
LTLYQSNTIL RHLGRTLGLY GKDQQEAALV DMVNDGVEDL RCKYISLIYT NYEAGKDDYV
       130        140        150        160        170        180
KALPGQLKPF ETLLSQNQGG KTFIVGDQIS FADYNLLDLL LIHEVLAPGC LDAFPLLSAY
       190        200        210
VGRLSARPKL KAFLASPEYV NLPINGNGKQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09211-1-unknown	MPPYTV...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P09211-2-unknown	PPYTVV...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09211-2-unknown	PPYTVV...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P09211-2-unknown	PPYTVV...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P09211-2-unmodified	PPYTVV...	2		other		CNRS/ISV	Large_scale_NTA_Human
P09211-4-	YTVVYF...	4		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P09211-4-	YTVVYF...	4		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09211-4-	YTVVYF...	4		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09211-5-	TVVYFP...	5		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09211-28-	SWKEEV...	28		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09211-51-unknown	GQLPKF...	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8445
P09211-59-unknown	GDLTLY...	59	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P09211-88-unknown	ALVDMV...	88	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11136
P09211-92-	MVNDGV...	92		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09211-92-	MVNDGV...	92		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ASCLYG	50	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8445
...DQQEAA	87	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11136
...GNGKQ	210		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...GNGKQ	210	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...GNGKQ	210		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CTRB2_HUMAN	50	CLYG.\|.GQLP	inferred from experiment	unknown	MEROPS	Di Ilio C	Martini F et al.:Investigation of intra-domain a... (S01.152)	8281936,
GRAB_HUMAN	87	QEAA.\|.ALVD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)