O00422: Histone deacetylase complex subunit SAP18

General Information

Protein names	- Histone deacetylase complex subunit SAP18 - 18 kDa Sin3-associated polypeptide - 2HOR0202 - Cell growth-inhibiting gene 38 protein - Sin3-associated polypeptide p18
Gene names	SAP18
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00422

4 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT
        70         80         90        100        110        120
WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM
       130        140        150
TLQSQKFQIG DYLDIAITPP NRAPPPSGRM RPY

Isoforms

- Isoform 2 of Histone deacetylase complex subunit SAP18

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O00422-2-unknown	MAVESR...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O00422-2-Acetylation	AVESRV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O00422-11-unknown	EIKKEP...	11		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10638
O00422-25-unknown	TCPLLL...	25		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475358

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RVTQEE	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10638
...LQIYTW	60	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475435
...RPGYRV	102	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475358
...RAPPPS	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391846
...RMRPY	153	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	10	TQEE.\|.EIKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)