P35268: 60S ribosomal protein L22

General Information

Protein names	- 60S ribosomal protein L22 - EBER-associated protein - EAP - Epstein-Barr virus small RNA-associated protein - Heparin-binding protein HBp15 - Large ribosomal subunit protein eL22 {ECO:0000303\|PubMed:24524803}
Gene names	RPL22
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35268

5 N-termini

9 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPVKKLVVK GGKKKKQVLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN GKAGNLGGGV
        70         80         90        100        110        120
VTIERSKSKI TVTSEVPFSK RYLKYLTKKY LKKNNLRDWL RVVANSKESY ELRYFQINQD

EEEEEDED

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 9 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P35268-2-unknown	APVKKL...	2	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P35268-24-unknown	DCTHPV...	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14092
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465763
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468274
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466502
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466013
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467247
P35268-34-unknown	MDAANF...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465313
P35268-68-unknown	SKITVT...	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19067
P35268-121-unknown	EEEEED...	121	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11456

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LKFTLD	23	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14092
...IERSKS	67	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19067
...VPFSKR	80	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465313
...PFSKRY	81	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467247
...ESYELR	112	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466013
...QINQDE	120	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11456
...NQDEEE	122	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466502
...EEDED	128	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EEDED	128		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EEDED	128		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	23	FTLD.\|.DCTH	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1B_HUMAN	67	RSKS.\|.SKIT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	120	NQDE.\|.EEEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)