O95218: Zinc finger Ran-binding domain-containing protein 2

General Information

Protein names	- Zinc finger Ran-binding domain-containing protein 2 - Zinc finger protein 265 - Zinc finger, splicing
Gene names	ZRANB2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95218

9 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTKNFRVSD GDWICPDKKC GNVNFARRTS CNRCGREKTT EAKMMKAGGT EIGKTLAEKS
        70         80         90        100        110        120
RGLFSANDWQ CKTCSNVNWA RRSECNMCNT PKYAKLEERT GYGGGFNERE NVEYIEREES
       130        140        150        160        170        180
DGEYDEFGRK KKKYRGKAVG PASILKEVED KESEGEEEDE DEDLSKYKLD EDEDEDDADL
       190        200        210        220        230        240
SKYNLDASEE EDSNKKKSNR RSRSKSRSSH SRSSSRSSSP SSSRSRSRSR SRSSSSSQSR
       250        260        270        280        290        300
SRSSSRERSR SRGSKSRSSS RSHRGSSSPR KRSYSSSSSS PERNRKRSRS RSSSSGDRKK
       310        320        330
RRTRSRSPER RHRSSSGSSH SGSRSSSKKK

Isoforms

- Isoform 2 of Zinc finger Ran-binding domain-containing protein 2

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95218-1-unknown	MSTKNF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95218-1-unknown	MSTKNF...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt95670
O95218-2-acetylation	STKNFR...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95218-2-acetylation	STKNFR...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95218-2-acetylation	STKNFR...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163201
O95218-18-unknown	KKCGNV...	18		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11008
O95218-18-unknown	KKCGNV...	18		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136686
O95218-46-unknown	KAGGTE...	46		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13870
O95218-46-unknown	KAGGTE...	46		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138820
O95218-138-unknown	AVGPAS...	138		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177349
O95218-138-	AVGPAS...	138			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
O95218-186-unknown	DASEEE...	186		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13872
O95218-186-unknown	DASEEE...	186		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146100
O95218-187-unknown	ASEEED...	187		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11010
O95218-187-unknown	ASEEED...	187		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146119
O95218-193-unknown	SNKKKS...	193		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11012
O95218-193-unknown	SNKKKS...	193		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146331

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...WICPDK	17	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11008
...EAKMMK	45	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13870
...EAKMMK	45	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121879
...SKYNLD	185	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13872
...SKYNLD	185	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129400
...KYNLDA	186	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11010
...KYNLDA	186	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129420
...SEEEDS	192	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11012
...SEEEDS	192	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129633
...SSKKK	330	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SSKKK	330		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SSKKK	330		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	17	CPDK.\|.KKCG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	45	KMMK.\|.KAGG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	185	YNLD.\|.DASE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	186	NLDA.\|.ASEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	192	EEDS.\|.SNKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)