Q9Y232: Chromodomain Y-like protein {ECO:0000303|PubMed:10192397}
Protein names | - Chromodomain Y-like protein {ECO:0000303|PubMed:10192397} - CDY-like {ECO:0000303|PubMed:10192397} - Crotonyl-CoA hydratase {ECO:0000303|PubMed:28803779} - 4.2.1.- {ECO:0000269|PubMed:28803779} |
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Gene names | CDYL |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9Y232 |
6
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA
70 80 90 100 110 120
LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES
130 140 150 160 170 180
TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS
190 200 210 220 230 240
LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP
250 260 270 280 290 300
VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN
310 320 330 340 350 360
IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK
370 380 390 400 410 420
SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES
430 440 450 460 470 480
TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ
490 500 510 520 530 540
SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL
550 560 570 580 590
ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
Isoforms
- Isoform 2 of Chromodomain Y-like protein - Isoform 3 of Chromodomain Y-like protein - Isoform 4 of Chromodomain Y-like proteinSequence View
10 20 30 40 50 60
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA
70 80 90 100 110 120
LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES
130 140 150 160 170 180
TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS
190 200 210 220 230 240
LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP
250 260 270 280 290 300
VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN
310 320 330 340 350 360
IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK
370 380 390 400 410 420
SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES
430 440 450 460 470 480
TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ
490 500 510 520 530 540
SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL
550 560 570 580 590
ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
10 20 30 40 50 60
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA
70 80 90 100 110 120
LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES
130 140 150 160 170 180
TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS
190 200 210 220 230 240
LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP
250 260 270 280 290 300
VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN
310 320 330 340 350 360
IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK
370 380 390 400 410 420
SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES
430 440 450 460 470 480
TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ
490 500 510 520 530 540
SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL
550 560 570 580 590
ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
10 20 30 40 50 60
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA
70 80 90 100 110 120
LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES
130 140 150 160 170 180
TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS
190 200 210 220 230 240
LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP
250 260 270 280 290 300
VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN
310 320 330 340 350 360
IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK
370 380 390 400 410 420
SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES
430 440 450 460 470 480
TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ
490 500 510 520 530 540
SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL
550 560 570 580 590
ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
Protein Neighborhood
Domains & Features
6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9Y232-1-unknown | MTFQAS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9Y232-187-unknown | MDLAKS... | 187 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt70159 | |||
Q9Y232-187-unknown | MDLAKS... | 187 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96672 | |||
Q9Y232-211-unknown | GFQSES... | 211 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173966 | |||
Q9Y232-211-unknown | GFQSES... | 211 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173967 | |||
Q9Y232-211- | GFQSES... | 211 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9Y232-211- | GFQSES... | 211 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9Y232-211- | GFQSES... | 211 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9Y232-211- | GFQSES... | 211 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9Y232-235-unknown | VAAEKP... | 235 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13595 | |||
Q9Y232-235-unknown | VAAEKP... | 235 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139048 | |||
Q9Y232-235-unknown | VAAEKP... | 235 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt145914 | |||
Q9Y232-290-unknown | MDALTA... | 290 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt70158 | |||
Q9Y232-290-unknown | MDALTA... | 290 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96612 | |||
Q9Y232-290-unknown | MDALTA... | 290 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96613 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...TVAPEV | 234 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13595 | |||
...TVAPEV | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122119 | |||
...TVAPEV | 234 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129211 | |||
...KIDEF | 598 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KIDEF | 598 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt65776 | |||
...KIDEF | 598 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt65777 | |||
...KIDEF | 598 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt65775 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 234 | APEV.|.VAAE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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