P36915: Guanine nucleotide-binding protein-like 1

General Information

Protein names	- Guanine nucleotide-binding protein-like 1 - GTP-binding protein HSR1
Gene names	GNL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P36915

7 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPRKKPFSVK QKKKQLQDKR ERKRGLQDGL RSSSNSRSGS RERREEQTDT SDGESVTHHI
        70         80         90        100        110        120
RRLNQQPSQG LGPRGYDPNR YRLHFERDSR EEVERRKRAA REQVLQPVSA ELLELDIREV
       130        140        150        160        170        180
YQPGSVLDFP RRPPWSYEMS KEQLMSQEER SFQDYLGKIH GAYSSEKLSY FEHNLETWRQ
       190        200        210        220        230        240
LWRVLEMSDI VLLITDIRHP VVNFPPALYE YVTGELGLAL VLVLNKVDLA PPALVVAWKH
       250        260        270        280        290        300
YFHQHYPQLH VVLFTSFPRD PRTPQDPSSV LKKSRRRGRG WTRALGPEQL LRACEAITVG
       310        320        330        340        350        360
KVDLSSWREK IARDVAGATW GNGSGEEEEE EDGPAVLVEQ QTDSAMEPTG PTQERYKDGV
       370        380        390        400        410        420
VTIGCVGFPN VGKSSLINGL VGRKVVSVSR TPGHTRYFQT YFLTPSVKLC DCPGLIFPSL
       430        440        450        460        470        480
LPRQLQVLAG IYPIAQIQEP YTAVGYLASR IPVQALLHLR HPEAEDPSAE HPWCAWDICE
       490        500        510        520        530        540
AWAEKRGYKT AKAARNDVYR AANSLLRLAV DGRLSLCFHP PGYSEQKGTW ESHPETTELV
       550        560        570        580        590        600
VLQGRVGPAG DEEEEEEEEL SSSCEEEGEE DRDADEEGEG DEETPTSAPG SSLAGRNPYA

LLGEDEC

Isoforms

- Isoform 2 of Guanine nucleotide-binding protein-like 1

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P36915-1-unknown	MPRKKP...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P36915-50-	TSDGES...	50		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P36915-112-unknown	LLELDI...	112	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11477
P36915-335-unknown	AVLVEQ...	335	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170579
P36915-335-	AVLVEQ...	335		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P36915-344-	SAMEPT...	344		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P36915-344-unknown	SAMEPT...	344		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P36915-344-unknown	SAMEPT...	344		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P36915-344-unknown	SAMEPT...	344	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159681

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PVSAEL	111	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11477
...GEDEC	607	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...GEDEC	607	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71780
...GEDEC	607		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...GEDEC	607		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...GEDEC	607		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...GEDEC	607		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	111	SAEL.\|.LLEL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)