TopFIND 4.0

Q5VTR2: E3 ubiquitin-protein ligase BRE1A

General Information

Protein names
- E3 ubiquitin-protein ligase BRE1A
- BRE1-A
- hBRE1
- 2.3.2.27 {ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:16337599, ECO:0000269|PubMed:19410543}
- RING finger protein 20
- RING-type E3 ubiquitin transferase BRE1A {ECO:0000305}
Gene names RNF20
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5VTR2

5

N-termini

5

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGIGNKRAA GEPGTSMPPE KKAAVEDSGT TVETIKLGGV SSTEELDIRT LQTKNRKLAE 
        70         80         90        100        110        120 
MLDQRQAIED ELREHIEKLE RRQATDDASL LIVNRYWSQF DENIRIILKR YDLEQGLGDL 
       130        140        150        160        170        180 
LTERKALVVP EPEPDSDSNQ ERKDDRERGE GQEPAFSFLA TLASSSSEEM ESQLQERVES 
       190        200        210        220        230        240 
SRRAVSQIVT VYDKLQEKVE LLSRKLNSGD NLIVEEAVQE LNSFLAQENM RLQELTDLLQ 
       250        260        270        280        290        300 
EKHRTMSQEF SKLQSKVETA ESRVSVLESM IDDLQWDIDK IRKREQRLNR HLAEVLERVN 
       310        320        330        340        350        360 
SKGYKVYGAG SSLYGGTITI NARKFEEMNA ELEENKELAQ NRLCELEKLR QDFEEVTTQN 
       370        380        390        400        410        420 
EKLKVELRSA VEQVVKETPE YRCMQSQFSV LYNESLQLKA HLDEARTLLH GTRGTHQHQV 
       430        440        450        460        470        480 
ELIERDEVSL HKKLRTEVIQ LEDTLAQVRK EYEMLRIEFE QTLAANEQAG PINREMRHLI 
       490        500        510        520        530        540 
SSLQNHNHQL KGEVLRYKRK LREAQSDLNK TRLRSGSALL QSQSSTEDPK DEPAELKPDS 
       550        560        570        580        590        600 
EDLSSQSSAS KASQEDANEI KSKRDEEERE RERREKERER EREREKEKER EREKQKLKES 
       610        620        630        640        650        660 
EKERDSAKDK EKGKHDDGRK KEAEIIKQLK IELKKAQESQ KEMKLLLDMY RSAPKEQRDK 
       670        680        690        700        710        720 
VQLMAAEKKS KAELEDLRQR LKDLEDKEKK ENKKMADEDA LRKIRAVEEQ IEYLQKKLAM 
       730        740        750        760        770        780 
AKQEEEALLS EMDVTGQAFE DMQEQNIRLM QQLREKDDAN FKLMSERIKS NQIHKLLKEE 
       790        800        810        820        830        840 
KEELADQVLT LKTQVDAQLQ VVRKLEEKEH LLQSNIGTGE KELGLRTQAL EMNKRKAMEA 
       850        860        870        880        890        900 
AQLADDLKAQ LELAQKKLHD FQDEIVENSV TKEKDMFNFK RAQEDISRLR RKLETTKKPD 
       910        920        930        940        950        960 
NVPKCDEILM EEIKDYKARL TCPCCNMRKK DAVLTKCFHV FCFECVKTRY DTRQRKCPKC 
       970    
NAAFGANDFH RIYIG

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)