Q86UY5: Protein FAM83A {ECO:0000305}
Protein names | - Protein FAM83A {ECO:0000305} - Tumor antigen BJ-TSA-9 {ECO:0000303|Ref.2} - Tumor-specific gene expressed in prostate protein {ECO:0000303|Ref.1} |
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Gene names | FAM83A |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q86UY5 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSRSRHLGKI RKRLEDVKSQ WVRPARADFS DNESARLATD ALLDGGSEAY WRVLSQEGEV
70 80 90 100 110 120
DFLSSVEAQY IQAQAREPPC PPDTLGGAEA GPKGLDSSSL QSGTYFPVAS EGSEPALLHS
130 140 150 160 170 180
WASAEKPYLK EKSSATVYFQ TVKHNNIRDL VRRCITRTSQ VLVILMDVFT DVEIFCDILE
190 200 210 220 230 240
AANKRGVFVC VLLDQGGVKL FQEMCDKVQI SDSHLKNISI RSVEGEIYCA KSGRKFAGQI
250 260 270 280 290 300
REKFIISDWR FVLSGSYSFT WLCGHVHRNI LSKFTGQAVE LFDEEFRHLY ASSKPVMGLK
310 320 330 340 350 360
SPRLVAPVPP GAAPANGRLS SSSGSASDRT SSNPFSGRSA GSHPGTRSVS ASSGPCSPAA
370 380 390 400 410 420
PHPPPPPRFQ PHQGPWGAPS PQAHLSPRPH DGPPAAVYSN LGAYRPTRLQ LEQLGLVPRL
430
TPTWRPFLQA SPHF
Isoforms
- Isoform 2 of Protein FAM83A - Isoform 3 of Protein FAM83ASequence View
10 20 30 40 50 60
MSRSRHLGKI RKRLEDVKSQ WVRPARADFS DNESARLATD ALLDGGSEAY WRVLSQEGEV
70 80 90 100 110 120
DFLSSVEAQY IQAQAREPPC PPDTLGGAEA GPKGLDSSSL QSGTYFPVAS EGSEPALLHS
130 140 150 160 170 180
WASAEKPYLK EKSSATVYFQ TVKHNNIRDL VRRCITRTSQ VLVILMDVFT DVEIFCDILE
190 200 210 220 230 240
AANKRGVFVC VLLDQGGVKL FQEMCDKVQI SDSHLKNISI RSVEGEIYCA KSGRKFAGQI
250 260 270 280 290 300
REKFIISDWR FVLSGSYSFT WLCGHVHRNI LSKFTGQAVE LFDEEFRHLY ASSKPVMGLK
310 320 330 340 350 360
SPRLVAPVPP GAAPANGRLS SSSGSASDRT SSNPFSGRSA GSHPGTRSVS ASSGPCSPAA
370 380 390 400 410 420
PHPPPPPRFQ PHQGPWGAPS PQAHLSPRPH DGPPAAVYSN LGAYRPTRLQ LEQLGLVPRL
430
TPTWRPFLQA SPHF
10 20 30 40 50 60
MSRSRHLGKI RKRLEDVKSQ WVRPARADFS DNESARLATD ALLDGGSEAY WRVLSQEGEV
70 80 90 100 110 120
DFLSSVEAQY IQAQAREPPC PPDTLGGAEA GPKGLDSSSL QSGTYFPVAS EGSEPALLHS
130 140 150 160 170 180
WASAEKPYLK EKSSATVYFQ TVKHNNIRDL VRRCITRTSQ VLVILMDVFT DVEIFCDILE
190 200 210 220 230 240
AANKRGVFVC VLLDQGGVKL FQEMCDKVQI SDSHLKNISI RSVEGEIYCA KSGRKFAGQI
250 260 270 280 290 300
REKFIISDWR FVLSGSYSFT WLCGHVHRNI LSKFTGQAVE LFDEEFRHLY ASSKPVMGLK
310 320 330 340 350 360
SPRLVAPVPP GAAPANGRLS SSSGSASDRT SSNPFSGRSA GSHPGTRSVS ASSGPCSPAA
370 380 390 400 410 420
PHPPPPPRFQ PHQGPWGAPS PQAHLSPRPH DGPPAAVYSN LGAYRPTRLQ LEQLGLVPRL
430
TPTWRPFLQA SPHF
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q86UY5-1-unknown | MSRSRH... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q86UY5-1-unknown | MSRSRH... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74683 | |||
Q86UY5-1-unknown | MSRSRH... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74684 | |||
Q86UY5-27-unknown | ADFSDN... | 27 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12755 | |||
Q86UY5-27-unknown | ADFSDN... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137363 | |||
Q86UY5-27-unknown | ADFSDN... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137364 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VRPARA | 26 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12755 | |||
...VRPARA | 26 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt120308 | |||
...VRPARA | 26 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt120309 | |||
...ASPHF | 434 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 26 | PARA.|.ADFS | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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