TopFIND 4.0

Q8IZ69: tRNA (uracil-5-)-methyltransferase homolog A

General Information

Protein names
- tRNA (uracil-5-)-methyltransferase homolog A
- 2.1.1.-
- HpaII tiny fragments locus 9c protein
Gene names TRMT2A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IZ69

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSENLDNEGP KPMESCGQES SSALSCPTVS VPPAAPAALE EVEKEGAGAA TGPGPQPGLY 
        70         80         90        100        110        120 
SYIRDDLFTS EIFKLELQNV PRHASFSDVR RFLGRFGLQP HKTKLFGQPP CAFVTFRSAA 
       130        140        150        160        170        180 
ERDKALRVLH GALWKGRPLS VRLARPKADP MARRRRQEGE SEPPVTRVAD VVTPLWTVPY 
       190        200        210        220        230        240 
AEQLERKQLE CEQVLQKLAK EIGSTNRALL PWLLEQRHKH NKACCPLEGV RPSPQQTEYR 
       250        260        270        280        290        300 
NKCEFLVGVG VDGEDNTVGC RLGKYKGGTC AVAAPFDTVH IPEATKQVVK AFQEFIRSTP 
       310        320        330        340        350        360 
YSAYDPETYT GHWKQLTVRT SRRHQAMAIA YFHPQKLSPE ELAELKTSLA QHFTAGPGRA 
       370        380        390        400        410        420 
SGVTCLYFVE EGQRKTPSQE GLPLEHVAGD RCIHEDLLGL TFRISPHAFF QVNTPAAEVL 
       430        440        450        460        470        480 
YTVIQDWAQL DAGSMVLDVC CGTGTIGLAL ARKVKRVIGV ELCPEAVEDA RVNAQDNELS 
       490        500        510        520        530        540 
NVEFHCGRAE DLVPTLVSRL ASQHLVAILD PPRAGLHSKV ILAIRRAKNL RRLLYVSCNP 
       550        560        570        580        590        600 
RAAMGNFVDL CRAPSNRVKG IPFRPVKAVA VDLFPQTPHC EMLILFERVE HPNGTGVLGP 
       610        620    
HSPPAQPTPG PPDNTLQETG TFPSS

Isoforms

- Isoform 2 of tRNA (uracil-5-)-methyltransferase homolog A

Sequence View

        10         20         30         40         50         60 
MSENLDNEGP KPMESCGQES SSALSCPTVS VPPAAPAALE EVEKEGAGAA TGPGPQPGLY 
        70         80         90        100        110        120 
SYIRDDLFTS EIFKLELQNV PRHASFSDVR RFLGRFGLQP HKTKLFGQPP CAFVTFRSAA 
       130        140        150        160        170        180 
ERDKALRVLH GALWKGRPLS VRLARPKADP MARRRRQEGE SEPPVTRVAD VVTPLWTVPY 
       190        200        210        220        230        240 
AEQLERKQLE CEQVLQKLAK EIGSTNRALL PWLLEQRHKH NKACCPLEGV RPSPQQTEYR 
       250        260        270        280        290        300 
NKCEFLVGVG VDGEDNTVGC RLGKYKGGTC AVAAPFDTVH IPEATKQVVK AFQEFIRSTP 
       310        320        330        340        350        360 
YSAYDPETYT GHWKQLTVRT SRRHQAMAIA YFHPQKLSPE ELAELKTSLA QHFTAGPGRA 
       370        380        390        400        410        420 
SGVTCLYFVE EGQRKTPSQE GLPLEHVAGD RCIHEDLLGL TFRISPHAFF QVNTPAAEVL 
       430        440        450        460        470        480 
YTVIQDWAQL DAGSMVLDVC CGTGTIGLAL ARKVKRVIGV ELCPEAVEDA RVNAQDNELS 
       490        500        510        520        530        540 
NVEFHCGRAE DLVPTLVSRL ASQHLVAILD PPRAGLHSKV ILAIRRAKNL RRLLYVSCNP 
       550        560        570        580        590        600 
RAAMGNFVDL CRAPSNRVKG IPFRPVKAVA VDLFPQTPHC EMLILFERVE HPNGTGVLGP 
       610        620    
HSPPAQPTPG PPDNTLQETG TFPSS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)