P50995: Annexin A11

General Information

Protein names	- Annexin A11 - 56 kDa autoantigen - Annexin XI - Annexin-11 - Calcyclin-associated annexin 50 - CAP-50
Gene names	ANXA11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P50995

12 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN QDYLSGMAAN
        70         80         90        100        110        120
MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV PPYGMYPPPG GNPPSRMPSY
       130        140        150        160        170        180
PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT
       190        200        210        220        230        240
PAVPPTQFGS RGTITDAPGF DPLRDAEVLR KAMKGFGTDE QAIIDCLGSR SNKQRQQILL
       250        260        270        280        290        300
SFKTAYGKDL IKDLKSELSG NFEKTILALM KTPVLFDIYE IKEAIKGVGT DEACLIEILA
       310        320        330        340        350        360
SRSNEHIREL NRAYKAEFKK TLEEAIRSDT SGHFQRLLIS LSQGNRDEST NVDMSLAQRD
       370        380        390        400        410        420
AQELYAAGEN RLGTDESKFN AVLCSRSRAH LVAVFNEYQR MTGRDIEKSI CREMSGDLEE
       430        440        450        460        470        480
GMLAVVKCLK NTPAFFAERL NKAMRGAGTK DRTLIRIMVS RSETDLLDIR SEYKRMYGKS
       490        500
LYHDISGDTS GDYRKILLKI CGGND

Isoforms

- Isoform 2 of Annexin A11

Sequence View

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Protein Neighborhood

Domains & Features

12 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P50995-1-unknown	MSYPGY...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P50995-34-unknown	MPPIGL...	34	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt67105
P50995-34-unknown	MPPIGL...	34	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000441400
P50995-178-	TVTPAV...	178		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P50995-178-unknown	TVTPAV...	178	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178455
P50995-189-unknown	GSRGTI...	189	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173650
P50995-189-	GSRGTI...	189		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P50995-192-	GTITDA...	192		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P50995-192-unknown	GTITDA...	192	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171285
P50995-193-unknown	TITDAP...	193	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173652
P50995-193-	TITDAP...	193		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P50995-220-unknown	EQAIID...	220	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11624
P50995-220-unknown	EQAIID...	220	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146147
P50995-292-unknown	EACLIE...	292	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11626
P50995-292-unknown	EACLIE...	292	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148776

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...GQPPVT	150	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000414642
...GQPPVT	150	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt109999
...GFGTDE	219	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11624
...GFGTDE	219	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129449
...GVGTDE	291	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11626
...GVGTDE	291	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt132152
...CGGND	505	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...CGGND	505	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt62723
...CGGND	505		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...CGGND	505		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	219	GTDE.\|.EQAI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	291	GTDE.\|.EACL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)