P40937: Replication factor C subunit 5

General Information

Protein names	- Replication factor C subunit 5 - Activator 1 36 kDa subunit - A1 36 kDa subunit - Activator 1 subunit 5 - Replication factor C 36 kDa subunit - RF-C 36 kDa subunit - RFC36
Gene names	RFC5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P40937

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
METSALKQQE QPAATKIRNL PWVEKYRPQT LNDLISHQDI LSTIQKFINE DRLPHLLLYG
        70         80         90        100        110        120
PPGTGKTSTI LACAKQLYKD KEFGSMVLEL NASDDRGIDI IRGPILSFAS TRTIFKKGFK
       130        140        150        160        170        180
LVILDEADAM TQDAQNALRR VIEKFTENTR FCLICNYLSK IIPALQSRCT RFRFGPLTPE
       190        200        210        220        230        240
LMVPRLEHVV EEEKVDISED GMKALVTLSS GDMRRALNIL QSTNMAFGKV TEETVYTCTG
       250        260        270        280        290        300
HPLKSDIANI LDWMLNQDFT TAYRNITELK TLKGLALHDI LTEIHLFVHR VDFPSSVRIH
       310        320        330        340
LLTKMADIEY RLSVGTNEKI QLSSLIAAFQ VTRDLIVAEA

Isoforms

- Isoform 2 of Replication factor C subunit 5

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P40937-1-Acetylation	METSAL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P40937-1-Acetylation	METSAL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P40937-1-Acetylation	METSAL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P40937-5-	ALKQQE...	5			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P40937-201-unknown	GMKALV...	201		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11499
P40937-201-unknown	GMKALV...	201		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145908

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DISEDG	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11499
...DISEDG	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129204
...IVAEA	340	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IVAEA	340	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82950

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	200	SEDG.\|.GMKA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)