Q8ND24: RING finger protein 214

General Information

Protein names	- RING finger protein 214
Gene names	RNF214
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8ND24

5 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASEVAGVV ANAPSPPESS SLCASKSDEG LPDGLSTKDS AQKQKNSPLL SVSSQTITKE
        70         80         90        100        110        120
NNRNVHLEHS EQNPGSSAGD TSAAHQVVLG ENLIATALCL SGSGSQSDLK DVASTAGEEG
       130        140        150        160        170        180
DTSLRESLHP VTRSLKAGCH TKQLASRNCS EEKSPQTSIL KEGNRDTSLD FRPVVSPANG
       190        200        210        220        230        240
VEGVRVDQDD DQDSSSLKLS QNIAVQTDFK TADSEVNTDQ DIEKNLDKMM TERTLLKERY
       250        260        270        280        290        300
QEVLDKQRQV ENQLQVQLKQ LQQRREEEMK NHQEILKAIQ DVTIKREETK KKIEKEKKEF
       310        320        330        340        350        360
LQKEQDLKAE IEKLCEKGRR EVWEMELDRL KNQDGEINRN IMEETERAWK AEILSLESRK
       370        380        390        400        410        420
ELLVLKLEEA EKEAELHLTY LKSTPPTLET VRSKQEWETR LNGVRIMKKN VRDQFNSHIQ
       430        440        450        460        470        480
LVRNGAKLSS LPQIPTPTLP PPPSETDFML QVFQPSPSLA PRMPFSIGQV TMPMVMPSAD
       490        500        510        520        530        540
PRSLSFPILN PALSQPSQPS SPLPGSHGRN SPGLGSLVSP HGPHMPPAAS IPPPPGLGGV
       550        560        570        580        590        600
KASAETPRPQ PVDKLEKILE KLLTRFPQCN KAQMTNILQQ IKTARTTMAG LTMEELIQLV
       610        620        630        640        650        660
AARLAEHERV AASTQPLGRI RALFPAPLAQ ISTPMFLPSA QVSYPGRSSH APATCKLCLM
       670        680        690        700
CQKLVQPSEL HPMACTHVLH KECIKFWAQT NTNDTCPFCP TLK

Isoforms

- Isoform 2 of RING finger protein 214

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8ND24-1-unknown	MAASEV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87951
Q8ND24-2-unknown	MAASEV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8ND24-2-Acetylation	AASEVA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8ND24-2-Acetylation	AASEVA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110792
Q8ND24-51-	SVSSQT...	51			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q8ND24-220-unknown	QDIEKN...	220		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12896
Q8ND24-220-unknown	QDIEKN...	220		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140295

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KQLASR	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434186
...EVNTDQ	219	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12896
...CPTLK	703	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...CPTLK	703	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83569

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	219	NTDQ.\|.QDIE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)