Q969G3: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

General Information

Protein names	- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 - BRG1-associated factor 57 - BAF57
Gene names	SMARCE1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q969G3

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 - Isoform 3 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 - Isoform 4 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 - Isoform 5 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 - Isoform 6 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

Sequence View

        10         20         30         40         50         60
MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP
        70         80         90        100        110        120
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE
       130        140        150        160        170        180
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD
       190        200        210        220        230        240
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK
       250        260        270        280        290        300
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ
       310        320        330        340        350        360
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG
       370        380        390        400        410
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E         10         20         30         40         50         60
MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP
        70         80         90        100        110        120
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE
       130        140        150        160        170        180
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD
       190        200        210        220        230        240
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK
       250        260        270        280        290        300
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ
       310        320        330        340        350        360
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG
       370        380        390        400        410
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E         10         20         30         40         50         60
MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP
        70         80         90        100        110        120
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE
       130        140        150        160        170        180
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD
       190        200        210        220        230        240
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK
       250        260        270        280        290        300
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ
       310        320        330        340        350        360
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG
       370        380        390        400        410
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E         10         20         30         40         50         60
MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP
        70         80         90        100        110        120
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE
       130        140        150        160        170        180
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD
       190        200        210        220        230        240
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK
       250        260        270        280        290        300
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ
       310        320        330        340        350        360
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG
       370        380        390        400        410
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E         10         20         30         40         50         60
MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP
        70         80         90        100        110        120
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE
       130        140        150        160        170        180
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD
       190        200        210        220        230        240
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK
       250        260        270        280        290        300
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ
       310        320        330        340        350        360
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG
       370        380        390        400        410
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q969G3-1-unknown	MSKRPS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969G3-1-unknown	MSKRPS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90017
Q969G3-71-unknown	MPYMRY...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90018
Q969G3-71-unknown	MPYMRY...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90021
Q969G3-71-unknown	MPYMRY...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104939
Q969G3-71-unknown	MPYMRY...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104940
Q969G3-71-unknown	MPYMRY...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104941
Q969G3-282-unknown	MEKIAA...	282	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13032
Q969G3-282-unknown	MEKIAA...	282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147069
Q969G3-282-unknown	MEKIAA...	282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147071
Q969G3-282-unknown	MEKIAA...	282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148342
Q969G3-282-unknown	MEKIAA...	282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148343
Q969G3-282-unknown	MEKIAA...	282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149408
Q969G3-317-unknown	SIVPEE...	317	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176002
Q969G3-317-unknown	SIVPEE...	317	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176005
Q969G3-317-unknown	SIVPEE...	317	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176003
Q969G3-317-unknown	SIVPEE...	317	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176004
Q969G3-317-unknown	SIVPEE...	317	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176006
Q969G3-317-	SIVPEE...	317		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q969G3-393-unknown	SATVEE...	393	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176009
Q969G3-393-unknown	SATVEE...	393	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176008
Q969G3-393-	SATVEE...	393		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q969G3-393-	SATVEE...	393		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVEVDM	281	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13032
...KVEVDM	281	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130402
...KVEVDM	281	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130404
...KVEVDM	281	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131713
...KVEVDM	281	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131714
...KVEVDM	281	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132793
...DEKKE	411	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DEKKE	411	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85636
...DEKKE	411	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85637

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	281	EVDM.\|.MEKI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)